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Z-Ser(Bzl)-OH

Z-Ser(Bzl)-OH structure

CAS No.: 20806-43-3

Chemical Name:: Z-Ser(Bzl)-OH

Synonyms: Cbz-Ser(Bzl);Z-Ser(Bzl)-OH;Z-L-Ser(Bzl)-OH;CBZ-SER(BZL)-OH;Z-SERINE(BZL)-OH;Cbz-L-Ser(Bzl)-OH;Z-Ser(Bzl)-OH,95 %;Z-O-BENZYL-L-SERINE;Cbz -O-benzyl-L-serine;Z-O-benzyl-L-serine99%

CBNumber:: CB8346456

Molecular Formula:: C18H19NO5

Molecular Weight:: 329.35

MDL Number:: MFCD00022029

MOL File:: 20806-43-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:55:40

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Z-Ser(Bzl)-OH Properties

Boiling point	537.1±50.0 °C(Predicted)
Density	1.253±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	3.51±0.10(Predicted)
color	White to off-white
optical activity	Consistent with structure
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	20806-43-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

NFPA 704

	1
0		0

Z-Ser(Bzl)-OH price More Price(52)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S776963	CARBOBENZYLOXY-O-BENZYL-L-SERINE Aldrich^CPR	20806-43-3	1 unit	$121	2026-04-30	Buy
Sigma-Aldrich	S776963	CARBOBENZYLOXY-O-BENZYL-L-SERINE AldrichCPR	20806-43-3	50MG	$110	2024-03-01	Buy
Biosynth	FC37793	Cbz-Ser(bzl)-OH	20806-43-3	5g	$163.3	2026-06-04	Buy
Biosynth	FC37793	Cbz-Ser(bzl)-OH	20806-43-3	10g	$290.3	2026-06-04	Buy
Biosynth	FC37793	Cbz-Ser(bzl)-OH	20806-43-3	25g	$453.75	2026-06-04	Buy

Product number	Packaging	Price	Buy
S776963	1 unit	$121	Buy
S776963	50MG	$110	Buy
FC37793	5g	$163.3	Buy
FC37793	10g	$290.3	Buy
FC37793	25g	$453.75	Buy

Z-Ser(Bzl)-OH Chemical Properties, Uses, Production

Uses

Cbz-Ser(Bzl)-OH is used in preparation of Aminoamide derivatives as anticancer agents.

Synthesis

4726-96-9

31139-36-3

20806-43-3

At room temperature, O-benzyl-L-serine (25.0 g, 128 mmol) was dissolved in a mixed solvent of water (200 mL) and dioxane (100 mL) and sodium carbonate (7.46 g, 70 mmol) was added. Subsequently, a solution of dibenzyl dicarbonate (36.1 g, 126 mmol) in dioxane (100 mL) was slowly added dropwise and the reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the dioxane was removed by vacuum evaporation and the remaining aqueous phase was extracted with ether. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under vacuum to give the crude product N-benzyloxycarbonyl-O-benzyl-L-serine (39.57 g, 95% yield) as a white solid, which was finally purified by washing with hexane.

References

[1] Liebigs Annalen der Chemie, 1994, # 6, p. 641 - 644
[2] Patent: US5030654, 1991, A
[3] Patent: EP274234, 1991, B1

Z-Ser(Bzl)-OH Preparation Products And Raw materials

Raw materials

O-Benzyl-L-serine Dibenzyl dicarbonate Sodium carbonate 1,4-Dioxane Water

Preparation Products

Z-Ser(Bzl)-OH Suppliers

Global Suppliers ( 150)

Supplier	Tel	Email	Country	ProdList	Advantage
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57
China Langchem Inc.	0086-21-58956006		China	7798	57
ChemPep, Inc.	+1 (888) 615-9178 / (561) 791-8787	service@chempep.com	United States	2138	57
Chengdu Ai Keda Chemical Technology Co., Ltd.	4008-755-333 18080918076	800078821@qq.com	China	9706	55
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12323	58

Supplier	Advantage
Alfa Aesar	84
GL Biochem (Shanghai) Ltd	64
Capot Chemical Co., Ltd	66
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Shandong Xiya Chemical Co., Ltd	57
China Langchem Inc.	57
ChemPep, Inc.	57
Chengdu Ai Keda Chemical Technology Co., Ltd.	55
Beijing HuaMeiHuLiBiological Chemical	58

View Latest Price from Z-Ser(Bzl)-OH manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-01	Z-SER(BZL)-OH 20806-43-3	$3.00	1KG	98%	100KG	Career Henan Chemical Co

Z-SER(BZL)-OH
20806-43-3
$3.00
98%
Career Henan Chemical Co

Z-Ser(Bzl)-OH Spectrum

Z-SER(BZL)-OH(20806-43-3)¹HNMR

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1of4

Z-SERINE(BZL)-OH Z-O-BENZYL-L-SERINE N-CARBOBENZOXY-O-BENZYL-L-SERINE N-ALPHA-CBZ-O-BENZYL-L-SERINE N-ALPHA-CARBOBENZOXY-O-BENZYL L-SERINE CBZ-SER(BZL)-OH BENZYLOXYCARBONYL-O-BENZYL-L-SERINE N-(benzyloxycarbonyl)-O-benzyl-L-serine Cbz -O-benzyl-L-serine N-alpha-Benzyloxycarbonyl-O-benzyl-L-serine Z-L-Ser(Bzl)-OH N-(Benzyloxycarbonyl)-O-benzylserine N-Cbz-O-Benzyl-L-Ser-OH 3-(benzyloxy)-2-(benzyloxycarbonylamino)propionic acid 3-(phenylmethoxy)-2-(phenylmethoxycarbonylamino)propanoic acid (2S)-3-(benzyloxy)-2-{[(benzyloxy)carbonyl]amino}propanoic acid L-Serine,N-[(phenylMethoxy)carbonyl]-O-(phenylMethyl)- Cbz-L-Ser(Bzl)-OH Z-O-benzyl-L-serine99% (S)-3-(Benzyloxy)-2-(((benzyloxy)carbonyl)amino)propanoicacid N-Benzyloxycarbonyl-O-benzyl-L-serine,95% (2S)-3-phenylmethoxy-2-(phenylmethoxycarbonylamino)propanoic acid (2S)-3-phenylmethoxy-2-(phenylmethoxycarbonylamino)propanoicaci Z-Ser(Bzl)-OH,95 % O-benzyl-N-((benzyloxy)carbonyl)-L-serine CARBOBENZYLOXY-O-BENZYL-L-SERINE Cbz-Ser(Bzl) Z-Ser(Bzl)-OH 20806-43-3