Robalzotan
- CAS No.
- 169758-66-1
- Chemical Name:
- Robalzotan
- Synonyms
- NAD 299;AZD7371;AZD 7371;AZD-7371;Robalzotan;NAD299; NAD-299;Unii-I18m56ogme;Robalzotan [inn];NAD 299 hydrochlorid;NAD 299 hydrochloride
- CBNumber:
- CB51179669
- Molecular Formula:
- C18H23FN2O2
- Molecular Weight:
- 318.39
- MDL Number:
- MOL File:
- 169758-66-1.mol
- MSDS File:
- SDS
| Boiling point | 429.9±45.0 °C(Predicted) |
|---|---|
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| pka | 15.72±0.40(Predicted) |
| FDA UNII | I18M56OGME |
Robalzotan price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 3282 | NAD299hydrochloride ≥98%(HPLC) | 169758-66-1 | 10 | $169 | 2021-12-16 | Buy |
| Tocris | 3282 | NAD299hydrochloride ≥98%(HPLC) | 169758-66-1 | 50 | $710 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009352 | ROBALZOTAN 95.00% | 169758-66-1 | 10MG | $721.59 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009352 | ROBALZOTAN 95.00% | 169758-66-1 | 50MG | $1327.97 | 2021-12-16 | Buy |
Robalzotan Chemical Properties, Uses, Production
Uses
NAD 299 Hydrochloride is a selective, high affinity 5-HT1A antagonist, used in psychotropic drug development.
Biological Activity
Selective, high affinity 5-HT 1A receptor antagonist (K i = 0.6 nM in vitro ).
in vivo
Robalzotan (1-100 μg/kg; i.v.) significantly increases the activity of such neurons at 5 μg/kg in rats, and reverses the acute inhibitory effect of citalopram (HY-121203) (300 μg/kg i.v.) or paroxetine (HY-122272) (100 μg/kg, i.v.) on the activity of 5-HT neurons in the dorsal raphe nucleus in rats[1].
Robalzotan (5, 50 μg/kg; i.v.) increases the firing rate of the 5-HT cells[1].
Robalzotan (2-100 μg/kg; i.v.) occupies 5-HT1A receptors in a dose-dependent in monkeys[2].
Robalzotan (0.3; 1 and 3 μmol/kg s.c) causes a dose-dependent increase of extracellular ACh levels in the rat FC[3].
IC 50
5-HT1A Receptor
Robalzotan Preparation Products And Raw materials
Raw materials
Preparation Products
Robalzotan Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 4988 | 55 |
| Shanghai Tube Pharmaceutical Co., Ltd. | 021-54338626 18017892860 | sales@tubepharm.com | China | 2709 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Foshan Heshuo Pharm technology Co., ltd | 15363639686 | heshuoyiyao@hotmail.com | China | 2488 | 58 |
| Shandong Ziyi Pharmaceutical Co., Ltd. | 17860786593 | 1181917242@qq.com | China | 9999 | 58 |
View Latest Price from Robalzotan manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Robalzotan
169758-66-1
|
$1970.00-3400.00 | 10g | TargetMol Chemicals Inc. |
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- Robalzotan
169758-66-1
- $1970.00-3400.00
- TargetMol Chemicals Inc.
