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2,3,5-Tri-O-benzyl-D-ribonolactone

2,3,5-Tri-O-benzyl-D-ribonolactone Structure
2,3,5-Tri-O-benzyl-D-ribonolactone structure
CAS No.
55094-52-5
Chemical Name:
2,3,5-Tri-O-benzyl-D-ribonolactone
Synonyms
2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone;1-Chloro-3,5-di-(p-chlorobenzoyl)-2-deoxy-D-ribofuranose;(3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxyMethyl)-dihydrofuran-2(3H)-one;2,3,5-Tri-O-benzyl-D-ribonic Acid 1,4-lactone;-D-RIBONO-1,4-L;JACS-55094-52-5;Redesivir Impurity 6;2,3, 5-tribenzoxy-d-ribonolactone;2,3,5-TRI-O-BENZYL-D-RIBONOLACTONE;Pentanedioicacid,7-oxo-,diethylester
CBNumber:
CB51180311
Molecular Formula:
C26H26O5
Molecular Weight:
418.49
MDL Number:
MFCD08703966
MOL File:
55094-52-5.mol
MSDS File:
SDS
Last updated:2026-05-28 01:29:56
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2,3,5-Tri-O-benzyl-D-ribonolactone Properties

Melting point 54-55 °C
Boiling point 576.8±50.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Sparingly), DMSO (Slightly, Sonicated), Methanol (Slightly)
form Solid
color White to Pale Yellow
optical activity Consistent with structure
InChI InChI=1/C26H26O5/c27-26-25(30-18-22-14-8-3-9-15-22)24(29-17-21-12-6-2-7-13-21)23(31-26)19-28-16-20-10-4-1-5-11-20/h1-15,23-25H,16-19H2/t23-,24-,25-/s3
InChIKey LDHBSABBBAUMCZ-HIIPYKDHNA-N
SMILES O([C@@H]1[C@H](OC(=O)[C@@H]1OCC1C=CC=CC=1)COCC1C=CC=CC=1)CC1C=CC=CC=1 |&1:1,2,6,r|

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
REACH Registrations Active

2,3,5-Tri-O-benzyl-D-ribonolactone price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T3955 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 55094-52-5 5G $70 2026-04-30 Buy
TCI Chemical T3955 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 55094-52-5 25G $208 2026-04-30 Buy
TRC TRC-T771378-5G 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 55094-52-5 5g $95 2026-06-03 Buy
TRC TRC-T771378-25G 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 55094-52-5 25g $237 2026-06-03 Buy
TRC TRC-T771378-2.5G 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 55094-52-5 2.5g $70 2026-06-03 Buy
Product number Packaging Price Buy
T3955 5G $70 Buy
T3955 25G $208 Buy
TRC-T771378-5G 5g $95 Buy
TRC-T771378-25G 25g $237 Buy
TRC-T771378-2.5G 2.5g $70 Buy

2,3,5-Tri-O-benzyl-D-ribonolactone Chemical Properties,Uses,Production

Physical Form

Solid

Application

2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a useful research chemical.

Synthesis

2,3,5-TRI-O-BENZYL-L-ARABINOFURANOSE

16838-89-4

3β,4α-Bis(benzyloxy)-5β-(benzyloxymethyl)tetrahydrofuran-2-one

14233-64-8

General procedure for the synthesis of 2,3,5-tribenzyloxy-D-arabinofuranous acid-1,4-lactone from 2,3,5-tri-O-(phenylmethyl)-D-ribofuranose: Compound 30a (prepared according to J. Org. Chem., 1961, 26, 4605; 10.0 g, 23.8 mmol) was dissolved in anhydrous DMSO (30 mL) and stirred under nitrogen protection. Acetic anhydride (20 mL) was then added and the reaction mixture was stirred continuously for 48 h at room temperature. After the completion of the reaction was monitored by LC/MS, the reaction mixture was slowly poured into ice water (500 mL) and stirring was continued for 20 min. The aqueous phase was extracted with ethyl acetate (3 × 200 mL), and the organic phase was combined and washed with deionized water (3 × 200 mL). The aqueous phase was discarded and the organic phase was dried over anhydrous MgSO4 and concentrated to dryness under reduced pressure. The residue was dissolved in dichloromethane (DCM) and purified by silica gel column chromatography using 25% ethyl acetate/hexane as eluent to give the target product 30b in 96% yield.1H-NMR (CD3CN) data: δ 3.63-3.75 (m, 2H), 4.27 (d, 1H), 4.50-4.57 (m, 3H), and 4.65 (s, 3H), 4.69-4.80 (m, 2H), 7.25 (d, 2H), 7.39 (m, 13H).

References

[1] Patent: WO2010/93608, 2010, A1. Location in patent: Page/Page column 158
[2] Patent: WO2011/35250, 2011, A1. Location in patent: Page/Page column 70-71
[3] Patent: WO2012/12776, 2012, A1. Location in patent: Page/Page column 109
[4] Patent: US2017/71964, 2017, A1. Location in patent: Paragraph 0517-0518
[5] Journal of Carbohydrate Chemistry, 2008, vol. 27, # 5, p. 332 - 344

2,3,5-Tri-O-benzyl-D-ribonolactone Preparation Products And Raw materials

Raw materials

2,3,5-Tri-O-benzyl-L-arabinofuranose

Preparation Products

2,3,5-Tri-O-benzyl-D-ribonolactone Suppliers

Global( 317)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Renshi Pharmatech Co., LTD 021-61150625 18521367657 info@renshipharma.com China 184 55
Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. 13632427122;13414494621 chenchao02lzu@126.com China 137 58
ABACHEM 13816002712 liu_wj@abachem.com China 19 58
Henan yu Chen pharmaceutical co., LTD 0374-5699939 18864655557 yuchenchem@126.com China 30 58
Jinan Kabotang Biological Technology Co.,Ltd. 0531-61320525 15866703830 figo.gao@foxmail.com China 7601 58
Changzhou Huihan Biotechnology Co., Ltd. 15380463325 15380463325 819573646@qq.com China 73 55
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Supplier Advantage
Shanghai Renshi Pharmatech Co., LTD 55
Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. 58
ABACHEM 58
Henan yu Chen pharmaceutical co., LTD 58
Jinan Kabotang Biological Technology Co.,Ltd. 58
Changzhou Huihan Biotechnology Co., Ltd. 55
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Capot Chemical Co., Ltd 66
Beijing Ouhe Technology Co., Ltd 60

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View Lastest Price from 2,3,5-Tri-O-benzyl-D-ribonolactone manufacturers

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2,3,5-Tri-O-benzyl-D-ribonolactone pictures 2026-09-11 2,3,5-Tri-O-benzyl-D-ribonolactone
55094-52-5
 $20000.00 1KG 99% 200kg/month Speranza Chemical Co., Ltd.
2,3,5-Tri-O-benzyl-D-ribonolactone pictures 2026-09-11 2,3,5-Tri-O-benzyl-D-ribonolactone
55094-52-5
 100g 98%min HPLC 100kg WUHAN FORTUNA CHEMICAL CO., LTD
2,3,5-Tri-O-benzyl-D-ribonolactone pictures 2026-06-30 2,3,5-Tri-O-benzyl-D-ribonolactone
55094-52-5
 1kg 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd

2,3,5-Tri-O-benzyl-D-ribonolactone Spectrum

2,3,5-Tri-O-benzyl-D-ribonolactone(55094-52-5)1HNMR

55094-52-5(2,3,5-Tri-O-benzyl-D-ribonolactone)Related Search:

D-Glucono-1,5-lactone Benzyl alcohol 4-Methoxybenzylchloride TRIOXSALEN Spironolactone
D-Glucurone Benzyl 2,3,5-Tri-O-benzoyl-2-C-methyl-D-ribonic acid-1,4-lactone D-ERYTHRONOLACTONE Ribonic acid
2,3,5-Tri-O-benzyl-D-ribose D(+)-Ribonic acid gamma-lactone D-LYXONO-1,4-LACTONE 5-O-Benzyl-D-ribose 2,3,5-Tri-O-benzyl-D-ribonolactone
(R)-3-Benzyloxy-pentanoic acid

1of4

2,3,5-TRI-O-BENZYL-D-RIBONOLACTONE (3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxyMethyl)-dihydrofuran-2(3H)-one 2,3,5-Tris-O-(phenylmethyl)-D-ribonic acid γ-lactone (3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]oxolan-2-one 2,2,5-tri-O-benzyl-D-ribono-1,4-lancton 2,3,5-Tri-O-benzyl-D-ribonic Acid 1,4-lactone JACS-55094-52-5 -D-RIBONO-1,4-L D-Ribonic acid, 2,3,5-tris-O-(phenylmethyl)-, γ-lactone 2,3,5-Tris-O-(phenylmethyl)-D-ribonic acid γ-lactone, 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 1, 4-lactone, 2,3, 5-tribenzoxy-D-ribosate-1, 4-lactone (3R,5R)-3,4--bis(phenylmethoxy)-5-(phenylmethoxyethyl)oxolan-2-one (3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-one (3R,4R,5R)-3,4-dibenzyloxy-5-(benzyloxymethyl)tetrahydrofuran-2-one Pentanedioicacid,7-oxo-,diethylester 2,3, 5-tribenzoxy-d-ribonolactone Redesivir Impurity 6 2,3,5-Tribenzyloxy-D-ribono-1,4-lactone 2,3,5-Tribenzyloxy-D-ribonicacid1,4-lactone 2,3,5-Tribenzyloxy-D-ribosyl-1,4-lactone 1-Chloro-3,5-di-(p-chlorobenzoyl)-2-deoxy-D-ribofuranose 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 55094-52-5 C26H26O5 J's 3 1