5-Nitro-2-indanone
- CAS No.
- 116530-60-0
- Chemical Name:
- 5-Nitro-2-indanone
- Synonyms
- 5-nitro-1H-inden-2(3H)-one;5-nitro-1,3-dihydroinden-2-one;5-NITRO-2-INDANONE;5-NITRO-INDAN-2-ONE;5-Nitro-2-Indanone(WX625103);5-nitro-2,3-dihydro-1H-inden-2-one;2H-Inden-2-one, 1,3-dihydro-5-nitro-
- CBNumber:
- CB5130816
- Molecular Formula:
- C9H7NO3
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD00598938
- MOL File:
- 116530-60-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Nitro-2-indanone Asreported | 285788 | 500mg | $360 |
| 5-Nitro-2-indanone Asreported | 285788 | 1g | $608 |
| 5-Nitro-2-indanone Asreported | 285788 | 2g | $852 |
| 5-Nitro-2-indanone Asreported | 285788 | 5g | $1201 |
| 5-NITRO-2-INDANONE 97% | 64652 | 1G | $65 |
| More product size | |||
| Boiling point | 340.6±42.0 °C(Predicted) |
|---|---|
| Density | 1.396±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| Appearance | Light brown to brown Solid |
| InChI | InChI=1S/C9H7NO3/c11-9-4-6-1-2-8(10(12)13)3-7(6)5-9/h1-3H,4-5H2 |
| InChIKey | VSEBFWRYDORZJI-UHFFFAOYSA-N |
| SMILES | C1C2=C(C=C([N+]([O-])=O)C=C2)CC1=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| HS Code | 2914790090 | |||||||||
| NFPA 704 |
|
5-Nitro-2-indanone price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 285788 | 5-Nitro-2-indanone Asreported | 116530-60-0 | 500mg | $360 | 2026-06-03 | Buy |
| Usbiological | 285788 | 5-Nitro-2-indanone Asreported | 116530-60-0 | 1g | $608 | 2026-06-03 | Buy |
| Usbiological | 285788 | 5-Nitro-2-indanone Asreported | 116530-60-0 | 2g | $852 | 2026-06-03 | Buy |
| Usbiological | 285788 | 5-Nitro-2-indanone Asreported | 116530-60-0 | 5g | $1201 | 2026-06-03 | Buy |
| AstaTech | 64652 | 5-NITRO-2-INDANONE 97% | 116530-60-0 | 1G | $65 | 2026-04-30 | Buy |
5-Nitro-2-indanone Chemical Properties,Uses,Production
Application
5-Nitro-2-indanone is a pharmaceutical intermediate that can be prepared from 2-indanol in four steps or from indanol by nitration followed by oxidation.
Synthesis
615-13-4
116530-60-0
Add 5.6 g of 2-indanone and 40 mL of chloroform to a 250 mL single neck flask. Measure 13 mL of 95% fuming nitric acid. Both were cooled in a cryogenic bath at a temperature below -20°C. The cooled 2-indanone was slowly added to the cooled fuming nitric acid. The dropwise addition process was continued for 40 minutes under vigorous stirring. The progress of the reaction was monitored by thin layer chromatography (TLC) (unfolding agent: chloroform:methanol=100:1, product Rf=0.64, 2-indanone Rf=0.79). After dropwise addition was complete, the reaction was continued at -20°C for 20 min to ensure complete reaction. The reaction was quenched with 60 mL of 10% sodium hydroxide solution mixed with ice water. The reaction mixture was layered in a dispensing funnel. The upper aqueous phase was extracted with chloroform (3 x 30 mL). The organic phases were combined and washed with saturated saline until neutral. The organic solvent was evaporated using a rotary evaporator to give a yellow solid. Recrystallized by ethyl acetate and cyclohexane and cooled to give reddish brown crystals. Upon filtration, 3.8 g of 5-nitro-2-indanone was obtained in 49.5% yield with a melting point of 141-143°C. The crystals were purified by filtration.
References
[1] Journal of the American Chemical Society, 1997, vol. 119, # 52, p. 12722 - 12726
[2] Patent: CN105315204, 2016, A. Location in patent: Paragraph 0028; 0032; 0033
[3] European Journal of Medicinal Chemistry, 2017, vol. 138, p. 738 - 747
[4] Chemische Berichte, 1899, vol. 32, p. 28,31
5-Nitro-2-indanone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +86-17717059219 | sales@rlavie.com | China | 1030 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49859 | 58 |
View Lastest Price from 5-Nitro-2-indanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-04 | 5-Nitro-2-indanone
116530-60-0
|
1g | 98%min | 50kgs/month | Shanghai Rlavie Technology Co ltd | ||
 |
2019-12-24 | 5-Nitro-2-indanone
116530-60-0
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 5-Nitro-2-indanone
116530-60-0
- 98%min
- Shanghai Rlavie Technology Co ltd
-
- 5-Nitro-2-indanone
116530-60-0
- $1.00
- 99%
- Career Henan Chemical Co
