CKS 17
- CAS No.
- 99273-04-8
- Chemical Name:
- CKS 17
- Synonyms
- Aids002113;Aids-002113;Lqnrrgldllflkeggl-bsa;CKS-17 (dimer), MN10021 - 1 mg;CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH;Leu-Gln-Asn-Arg-arg-Gly-Leu-Asp-Leu-leu-Phe-Leu-Lys-Glu-Gly-gly-Leu linked to bsa;L-Leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-L-leucine;L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-;L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-.alpha.-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-.alpha.-glutamylglycylglycyl-
- CBNumber:
- CB51317175
- Molecular Formula:
- C87H148N26O24
- Molecular Weight:
- 1942.28
- MDL Number:
- MOL File:
- 99273-04-8.mol
CKS 17 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FC110174 | CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH | 99273-04-8 | 500ug | $185 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC110174 | CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH | 99273-04-8 | 1mg | $319 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC110174 | CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH | 99273-04-8 | 2mg | $542 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0001110 | CKS-17 95.00% | 99273-04-8 | 0.5MG | $594.25 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0001110 | CKS-17 95.00% | 99273-04-8 | 1MG | $678.29 | 2021-12-16 | Buy |
CKS 17 Chemical Properties,Uses,Production
Uses
CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions[1][2][3].
in vivo
CKS-17 (10 μM; i.d.; B6AF1 mice and C57BL/6J mice) inhibits delayed-type hypersensitivity (DTH) reactions to sheep erythrocytes in the feet of mice[2].
| Animal Model: | B6AF1 mice and C57BL/6J mice with DTH models[2] |
| Dosage: | 10 μM |
| Administration: | Intradermal injection, into the right hind footpad |
| Result: | Had a transient depressive effect on DTH reaction. |
References
[1] Haraguchi S, et, al. Induction of intracellular cAMP by a synthetic retroviral envelope peptide: a possible mechanism of immunopathogenesis in retroviral infections. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5568-71. DOI:10.1073/pnas.92.12.5568
[2] Nelson M, et, al. Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: immunosuppression, immunogenicity, and relation to immunosuppressive tumor products. Cancer Immunol Immunother. 1989;30(2):113-8. DOI:10.1007/BF01665962
[3] Nelson M, et, al. Inhibition of interleukin-2 production by tumor cell products and by CKS-17, a synthetic retroviral envelope peptide. Cancer Immunol Immunother. 1990;30(6):331-41. DOI:10.1007/BF01786882
CKS 17 Preparation Products And Raw materials
Raw materials
Preparation Products
CKS 17 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Nanjing TGpeptide | +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5218 | 58 |
| Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 10000 | 58 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15402 | 60 |
| Nanjing Leon Biological Technology Co., Ltd. | 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9979 | 55 |
