BUTEIN
- CAS No.
- 21849-70-7
- Chemical Name:
- BUTEIN
- Synonyms
- BUTEIN;C08578;NSC 652892;2',3,4,4'-TETRAHYDROCHALCONE;3,4,2',4'-TETRAHYDROXYCHALCONE;2',4',3,4-TETRAHYDROXYCHALCONE;2',3,4,4'-TETRAHYDROXYCHALCONE;2’,4’-dihydroxy-3-(3,4-dihydroxyphenyl)-acrylophenon;1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-on;1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE
- CBNumber:
- CB5136454
- Molecular Formula:
- C15H12O5
- Molecular Weight:
- 272.25
- MDL Number:
- MFCD00017300
- MOL File:
- 21849-70-7.mol
| Melting point | 250-252℃ |
|---|---|
| Boiling point | 560.9±50.0 °C(Predicted) |
| Density | 1.483±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO: >50 mg/mL |
| form | solid |
| pka | 7.34±0.35(Predicted) |
| color | yellow |
| FDA UNII | 4WVS5M0LGF |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
BUTEIN Chemical Properties, Uses, Production
Uses
Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent.
Definition
ChEBI: Butein is a chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'. It has a role as a tyrosine kinase inhibitor, an antioxidant, an EC 1.1.1.21 (aldehyde reductase) inhibitor, an antineoplastic agent, a geroprotector, a radiosensitizing agent, a hypoglycemic agent and a plant metabolite. It is a member of chalcones and a polyphenol.
BUTEIN Preparation Products And Raw materials
Raw materials
Preparation Products
BUTEIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| Supplier | Advantage |
|---|---|
| AdooQ BioScience, LLC | 58 |
