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Ro 41-3290

Ro 41-3290 Structure
Ro 41-3290 structure
CAS No.
143943-72-0
Chemical Name:
Ro 41-3290
Synonyms
Ro 41-3290;Ro 41 3290,Ro 413290;3-Pyrrolidinol, 1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quinolizin-1-yl)carbonyl]-, (3S)- (9CI)
CBNumber:
CB51400804
Molecular Formula:
C24H21ClN2O3
Molecular Weight:
420.89
MDL Number:
MFCD20273193
MOL File:
143943-72-0.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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Ro 41-3290 Properties

Boiling point 723.3±60.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 14.47±0.20(Predicted)
FDA UNII EIR1Q66583

Ro 41-3290 Chemical Properties, Uses, Production

Uses

Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is a nonbenzodiazepine partial agonist at the benzodiazepine receptor.

in vivo

At all times plasma levels of Ro 41-3290, the desethylated derivative of Ro 41-3696, are higher than those of the parent drug (tmax and t1/2 values=~2 and 8 hours, respectively)[1]. Pharmacokinetics of both Ro 41-3696 and its O-desethyl metabolite Ro 41-3290 are dose proportional and time independent. Ro 41-3696 is absorbed and eliminates rapidly (time of maximum plasma concentration, approximately 1 hour; elimination half-life, approximately 2 hours). Plasma levels of Ro 41-3290 are higher than those of the parent drug, and it is more slowly eliminated (values for time of maximum plasma concentration and elimination half-life, approximately 2 and approximately 7 hours, respectively)[2].

References

[1] Dingemanse J, et al. Pharmacokinetics and pharmacodynamics of Ro 41-3696, a novel nonbenzodiazepine hypnotic. J Clin Pharmacol. 1995 Aug;35(8):821-9. DOI:10.1002/j.1552-4604.1995.tb04126.x
[2] Dingemanse J, et al. Multiple-dose tolerability, pharmacodynamics, and pharmacokinetics of the quinolizinone hypnotic Ro 41-3696 in elderly subjects. Clin Neuropharmacol. 2001 Mar-Apr;24(2):82-90. DOI:10.1097/00002826-200103000-00003

Ro 41-3290 Preparation Products And Raw materials

Raw materials

Preparation Products

Ro 41-3290 Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
MedChemexpress LLC 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from Ro 41-3290 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ro 41-3290 pictures 2026-04-21 Ro 41-3290
143943-72-0
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
Ro 41-3290 pictures 2025-08-22 Ro 41-3290
143943-72-0
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
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  • Ro 41-3290
    143943-72-0
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  • Ro 41-3290 pictures
  • Ro 41-3290
    143943-72-0
  • $1520.00-2500.00
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Ro 41-3290 3-Pyrrolidinol, 1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quinolizin-1-yl)carbonyl]-, (3S)- (9CI) Ro 41 3290,Ro 413290 143943-72-0