AcrB-IN-3
- CAS No.
- 2890177-94-1
- Chemical Name:
- AcrB-IN-3
- Synonyms
- AcrB-IN-3
- CBNumber:
- CB514245708
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
AcrB-IN-3 Chemical Properties,Uses,Production
Uses
Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model[1].
in vivo
Efflux pump-IN-3 (compound G10) (128 μg/mL; 72 h) shows no significant and in vivo toxicity against Caenorhabditis elegans[1].
References
[1] Guo T, et al. Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance. Eur J Med Chem. 2023 Mar 5;249:115148. DOI:10.1016/j.ejmech.2023.115148
AcrB-IN-3 Preparation Products And Raw materials
Raw materials
Preparation Products
AcrB-IN-3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Biorbyt Ltd. | -- | info@biorbyt.com | CHINA | 6482 | 58 |
| Supplier | Advantage |
|---|---|
| Biorbyt Ltd. | 58 |