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2-Amino-5-nitrothiazole

2-Amino-5-nitrothiazole structure

CAS No.: 121-66-4

Chemical Name:: 2-Amino-5-nitrothiazole

Synonyms: 5-Nitrothiazol-2-amine;ENHEPTIN;ENHEPTYNE;5-NITRO-1,3-THIAZOL-2-AMINE;Nitazoxanide Related Compound A (25 mg) (2-Amino-5-nitrothiazole);NSC 4;entramin;AKOS 203;ENTRAMINE;enheptint

CBNumber:: CB5143401

Molecular Formula:: C3H3N3O2S

Molecular Weight:: 145.14

MDL Number:: MFCD00005326

MOL File:: 121-66-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-10 10:27:18

Product description	Number	Pack Size	Price
Nitazoxanide Related Compound A pharmaceutical secondary standard, certified reference material	PHR2889	50MG	$601
2-Amino-5-nitrothiazole 97%	133507	25g	$47.8
2-Amino-5-nitrothiazole 97%	133507	100g	$170
2-Amino-5-nitrothiazole >98.0%(HPLC)(T)	A0381	25g	$85
2-Amino-5-nitrothiazole >98.0%(HPLC)(T)	A0381	500g	$993
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2-Amino-5-nitrothiazole Properties

Melting point	195-200 °C (dec.) (lit.)
Boiling point	345.1±15.0 °C(Predicted)
Density	1.583 (estimate)
refractive index	1.6740 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	95% ethanol: soluble1g/150g at 20°C
form	Powder
pka	1.26±0.10(Predicted)
color	Yellow
Water Solubility	<0.1 g/100 mL at 20 ºC
Sensitive	Light Sensitive
Merck	14,457
BRN	126797
Henry's Law Constant	1.9×10⁶ mol/(m³Pa) at 25℃, HSDB (2015)
Stability	Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides.
InChI	1S/C3H3N3O2S/c4-3-5-1-2(9-3)6(7)8/h1H,(H2,4,5)
InChIKey	MIHADVKEHAFNPG-UHFFFAOYSA-N
SMILES	Nc1ncc(s1)[N+]([O-])=O
Toxicology and Carcinogenesis	Bioassay of 2-Amino-5-Nitrothiazole for Possible Carcinogenicity (CASRN 121-66-4)
CAS DataBase Reference	121-66-4(CAS DataBase Reference)
FDA UNII	1GR77A37Z5
IARC	3 (Vol. 31, Sup 7) 1987
EPA Substance Registry System	2-Amino-5-nitrothiazole (121-66-4)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

22-36/37/38

Safety Statements

WGK Germany

RTECS

XJ2800000

Hazard Note

Irritant

TSCA

TSCA listed

HS Code

29341000

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Hazardous Substances Data

121-66-4(Hazardous Substances Data)

NFPA 704

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2-Amino-5-nitrothiazole price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR2889	Nitazoxanide Related Compound A pharmaceutical secondary standard, certified reference material	121-66-4	50MG	$601	2026-04-30	Buy
Sigma-Aldrich	133507	2-Amino-5-nitrothiazole 97%	121-66-4	25g	$47.8	2026-04-30	Buy
Sigma-Aldrich	133507	2-Amino-5-nitrothiazole 97%	121-66-4	100g	$170	2026-04-30	Buy
TCI Chemical	A0381	2-Amino-5-nitrothiazole >98.0%(HPLC)(T)	121-66-4	25g	$85	2026-04-30	Buy
TCI Chemical	A0381	2-Amino-5-nitrothiazole >98.0%(HPLC)(T)	121-66-4	500g	$993	2023-06-20	Buy

Product number	Packaging	Price	Buy
PHR2889	50MG	$601	Buy
133507	25g	$47.8	Buy
133507	100g	$170	Buy
A0381	25g	$85	Buy
A0381	500g	$993	Buy

2-Amino-5-nitrothiazole Chemical Properties,Uses,Production

Uses

Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole.

Chemical Properties

greenish yellow, to orange or brown powder

Uses

2-Amino-5-nitrothiazole was used as diazo component in the synthesis of monoazo disperse dyes. It was used as matrix during matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of oligonucleotide and protein.

Definition

ChEBI: 2-Amino-5-nitrothiazole is a member of thiazoles and a C-nitro compound.

Production Methods

Early production of 2-Amino-5-nitrothiazole was based on nitration of 2-acetylaminothiazole and careful hydrolysis. Direct nitration of 2-aminothiazole gives a cleaner product and is best achieved by adding 2-aminothiazole nitrate [57530-25-3] to concentrated sulfuric acid at 0 – 10 ℃. This process and the nitration of o-anisidine are the only large-scale processes based on rearrangement of an amine nitrate, and both are potentially hazardous due to the possibility of runaway exothermic reactions.

General Description

Greenish-yellow to orange-yellow fluffy powder or a brown chunky powder. Slightly bitter taste. Used as a veterinary medicine.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Amino-5-nitrothiazole may be sensitive to light. Incompatible with nitric acid and sulfuric acid. Also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. A preparative hazard .

Fire Hazard

Flash point data for 2-Amino-5-nitrothiazole are not available. 2-Amino-5-nitrothiazole is probably combustible.

Safety Profile

Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SO,. Incompatible with HNO3 and H2SO4. An antiprotozoal agent.

Potential Exposure

2-Amino-5-nitrothiazole is a synthetic veterinary antiprotozoal agent used since 1950 to treat farm fowl and pigeons. It is also used as an intermediate in manufacturing a group of dyes known as disperse azo dyes. It is not known to occur as a natural product. People may be exposed to 2-amino-5-nitrothiazole through contact with birds treated with the drug, releases from poultry farms, and occupational exposures in the dye industry.

2-Amino-5-nitrothiazole synthesis

Synthesis of 2-Amino-5-nitrothiazole from 2-Aminothiazole

2-Amino-5-nitrothiazole Preparation Products And Raw materials

Raw materials

2-Aminothiazole Sulfuric acid Thiourea

Preparation Products

2-CHLORO-5-NITROTHIAZOLE 2-[N-ethyl-4-[(5-nitrothiazol-2-yl)azo]-m-toluidino]ethyl acetate 2-Bromo-5-nitrothiazole C.I. Disperse Blue 295 press cake 3-[ethyl[3-methyl-4-[(5-nitrothiazol-2-yl)azo]phenyl]amino]propane-1,2-diol

Disperse Blue 284 DISPERSE BLUE 102 C.I. Disperse Blue 107 2-[ethyl[3-methyl-4-[(5-nitrothiazol-2-yl)azo]phenyl]amino]ethanol DISPERSE BLUE 124

Disperse Blue 339 2,2'-[3-methyl-4-(5-nitrothiazol-2-ylazo)phenylimino]bisethanol Disperse Blue 284 DISPERSE VIOLET 48 2-[ethyl[3-methyl-4-[(5-nitrothiazol-2-yl)azo]phenyl]amino]ethanol

Nitazoxanide Ethyl [(5-nitro-1,3-thiazol-2-yl)amino](oxo)acetate N-(5-nitro-2-thiazolyl)benzamide tenonitrozole Methyl 1-[[2-N-(5-Nitrothiazolyl)carboxamido]phenyl]-2,3,4- tri-O-acetyl--D-glucopyranuronate

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2-Amino-5-nitrothiazole Suppliers

Global( 521)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Qinmu Fine Chemical Co.,Ltd.	+8618660799346	sales@qinmuchem.com	China	1008	58
Hangzhou Verychem Science And Technology Co.Ltd	+86-86-57188162785 13606544505	lucy@verychem.com	China	1193	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	027-88013699 17354350817	Ryan@jiutian-bio.com	China	5945	58
Anhui Royal Chemical Co., Ltd.	+86-025-86655873 +86-13962173137	marketing@royal-chem.com	China	201	55
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5235	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Shandong Juchuang Chemical Co., LTD	+16837774622	admin@juchuangchem.com	China	295	58

Supplier	Advantage
Jinan Qinmu Fine Chemical Co.,Ltd.	58
Hangzhou Verychem Science And Technology Co.Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	58
Anhui Royal Chemical Co., Ltd.	55
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Shandong Juchuang Chemical Co., LTD	58

2-Amino-5-nitrothiazole: A Normal Heterocyclic Amine
2-Amino-5-nitrothiazole (heterocyclic amine) is a dye precursor, and carcinogenic in male rats; it serves as a head group for ....
Dec 23，2025

Synthesis of 2-Amino-5-nitrothiazole
A new synthetic process for 2-Amino-5-nitrothiazole avoids dangerous nitration and rearrangement procedures.
May 8，2024

View Lastest Price from 2-Amino-5-nitrothiazole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-30	2-Amino-5-nitrothiazole 121-66-4	US $350.00 / kg	200kg	99%	5 tons	Anhui Royal Chemical Co., Ltd.
2026-04-30	2-Amino-5-nitrothiazole 121-66-4	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-04-24	2-Amino-5-nitrothiazole 121-66-4	US $45.00 / T	1T	98%	1-200mt	Baoji Guokang Healthchem Co., Ltd.

2-Amino-5-nitrothiazole
121-66-4
US $350.00 / kg
99%
Anhui Royal Chemical Co., Ltd.

2-Amino-5-nitrothiazole
121-66-4
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-Amino-5-nitrothiazole
121-66-4
US $45.00 / T
98%
Baoji Guokang Healthchem Co., Ltd.

2-Amino-5-nitrothiazole Spectrum

2-Amino-5-nitrothiazole(121-66-4)MS 2-Amino-5-nitrothiazole(121-66-4)¹HNMR 2-Amino-5-nitrothiazole(121-66-4)IR1 2-Amino-5-nitrothiazole(121-66-4)IR2 2-Amino-5-nitrothiazole(121-66-4)Raman

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2-amino-5-nitro-thiazol 5-nitro-2-thiazolamin 5-nitro-2-Thiazolamine 5-nitro-2-thiazolylamine enheptin-t entramin nci-c03065 nitraminido usafek-6561 ENHEPTYNE ENTRAMINE AURORA KA-644 LABOTEST-BB LT00129612 AKOS BBS-00006479 AKOS 203 5-nitro-2-aminothiazole 2-AMINO-5-NITRO-1,3-THIAZOLE 2-AMINO-5-NITROTHIAZOLE 2-AMINO-5-NITRO-THIAZOLE HYDROCHLORIDE aminonitrothiazole aminonitrothiazolum aminzolsoluble amnizolsoluble enheptinpremix enheptint 5-nitrothiazol-2-ylamine Nitazoxanide Related Compound A (25 mg) (2-Amino-5-nitrothiazole) 2-AMino-5-nitrothiazole, 97% 100GR 2-Amino-5-nitrothiozole NSC 4 Nitazoxanide Related CoMpound A 2- aMino-5- nitrothiazolyl 2-AMINO-5-NITROTHIAZOLE CRYSTALLINE 2-Amino-5-NitroThiazole(Ant)99% 2-Amino-5-Nitro Thiazole (Ant) 99% 2-Thiazolamine, 5-nitro- 2-Amino-5-nitro thiazole 99% (ANT) 2-AMINO-5-NITROTHIAZOLE 98+% 2-AMINO-5-NITRO-THIAZOL HYDROCHLORIDE 2-Amino-5-nitrothiazole;Enheptyne 2-Amino-5-nitrothiazole,97% 2-Amino-5-Nitrothiazole sky Nitazoxanide Impurity 3（Nitazoxanide USP RC A） 2-AMINO-5-NITROTHIAZOLE 99+% 2-Amino-5-nitrothiazole > Nitazoxanide USP Related Compound A Nitazoxanide USP RC A Nitazoxanide Related Compound A (25 mg) 2-Amino-5-nitrothiazole ISO 9001：2015 REACH Hot Sale 2-Amino-5-nitrothiazole CAS 121-66-4 in Stock 5-Nitrothiazole-2-amine Nitazoxanide Related Compound A (2-Amino-5-nitrothiazole) (1463971) 2-Amino-5-nitrothiazole in methanol ENHEPTIN 5-NITRO-1,3-THIAZOL-2-AMINE 5-Nitrothiazol-2-amine 121-66-4 1880-01-3

2-Amino-5-nitrothiazole

2-Amino-5-nitrothiazole Properties

SAFETY

Risk and Safety Statements

2-Amino-5-nitrothiazole price More Price(39)

2-Amino-5-nitrothiazole Chemical Properties,Uses,Production

Uses

Chemical Properties

Uses

Definition

Production Methods

General Description

Air & Water Reactions

Reactivity Profile

Fire Hazard

Safety Profile

Potential Exposure

2-Amino-5-nitrothiazole synthesis

2-Amino-5-nitrothiazole Preparation Products And Raw materials

Raw materials

Preparation Products

2-Amino-5-nitrothiazole Suppliers

Related articles

View Lastest Price from 2-Amino-5-nitrothiazole manufacturers

2-Amino-5-nitrothiazole Spectrum

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