Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)-
- CAS No.
- 923289-36-5
- Chemical Name:
- Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)-
- Synonyms
- 6-ACETYL-2-CHLORO-3-METHOXY ANILINE;1-(2-Amino-3-chloro-4-methoxyphenyl);(2-Amino-3-chloro-4-methoxyphenyl)acetone;2'-Amino-3'-chloro-4'-methoxyacetophenone;1-(2-Amino-3-chloro-4-methoxyphenyl)ethanone;1-(2-aMino-3-chloro-4-Methoxyphenyl)ethan-1-one;Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)-;1-(2-Amino-3-chloro-4-methoxyphenyl)ethan-1-one, 6-Acetyl-2-chloro-3-methoxyaniline, 4-Acetyl-3-amino-2-chloroanisole
- CBNumber:
- CB51465766
- Molecular Formula:
- C9H10ClNO2
- Molecular Weight:
- 199.63
- MDL Number:
- MOL File:
- 923289-36-5.mol
- MSDS File:
- SDS
Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)- price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR70134 | 2'-Amino-3'-chloro-4'-methoxyacetophenone 95% | 923289-36-5 | 250mg | $22 | 2026-06-04 | Buy |
| aablocks | AA006KCZ | 1-(2-Amino-3-Chloro-4-Methoxyphenyl)Ethanone 95% | 923289-36-5 | 250mg | $96 | 2026-05-28 | Buy |
| aablocks | AA006KCZ | 1-(2-Amino-3-Chloro-4-Methoxyphenyl)Ethanone 95% | 923289-36-5 | 1g | $229 | 2026-05-28 | Buy |
| Crysdot | CD12006461 | 1-(2-Amino-3-chloro-4-methoxyphenyl)ethanone 95+% | 923289-36-5 | 1g | $239 | 2026-05-27 | Buy |
| Crysdot | CD12006461 | 1-(2-Amino-3-chloro-4-methoxyphenyl)ethanone 95+% | 923289-36-5 | 5g | $708 | 2026-05-27 | Buy |
Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)- Chemical Properties, Uses, Production
Synthesis
75-05-8
923289-36-5
General procedure for the synthesis of 1-(2-amino-3-chloro-4-methoxyphenyl)ethanone from acetonitrile: Step A: A dichloromethane solution of boron trichloride (1.0 M, 138 mL, 138 mmol) was slowly added to a solution of 2-chloro-3-methoxyaniline (20.6 g, 131 mmol) in xylene (225 mL) under nitrogen protection. The temperature was monitored during the addition to ensure that the temperature remained below 10°C. The reaction mixture was stirred at 5 °C for 0.5 hours. Subsequently, anhydrous acetonitrile (9.0 mL, 170 mmol) was added at 5 °C. After 0.5 h, the solution was transferred to a dropping funnel and slowly added to a pre-prepared suspension of aluminum trichloride (18.4 g, 138 mmol) in dichloromethane (80 mL). After reacting at 5°C for 45 min, the reaction mixture was heated to 70°C under a stream of nitrogen. After the dichloromethane evaporated, the temperature of the reaction mixture was raised to 65°C and the reaction was kept at this temperature for 12 hours. After completion of the reaction, the mixture was cooled to 0°C, poured into ice (200 g) and slowly heated to reflux for 7 hours. After standing at room temperature for 2 days, 6N sodium hydroxide solution (25 mL) and dichloromethane (100 mL) were added. The mixture was filtered and the filtrate was washed with dichloromethane. The organic layer was separated and washed sequentially with water, 1N sodium hydroxide solution and brine, dried over anhydrous sodium sulfate and the solvent evaporated. The residue was ground with diisopropyl ether at 0 °C, filtered and washed with diisopropyl ether to give 19.0 g (73% yield) of the target product 1-(2-amino-3-chloro-4-methoxyphenyl)ethanone (50) as a white solid with a mass spectrum showing m/z = 200 (M + H)+.
References
[1] Patent: WO2007/14926, 2007, A1. Location in patent: Page/Page column 78
Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)- Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| DanYang Ruihui Chemical Co.,Ltd | 0511-86883198 | sales@rhchemical.com | China | 33 | 58 |
| SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD | 13816107857 | sales@fortunechem-sh.com | China | 981 | 58 |
| HBCChem, Inc. | +1-510-219-6317 | sales@hbcchem.com | United States | 10628 | 60 |
| Modachem Shanghai Co., Ltd | +86 (0)21 51320687 51371369 1744605818 | China | 1576 | 58 |
View Latest Price from Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-08-30 | Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)-
923289-36-5
|
$1.00 | 1KG | 95%-99% | 100KG | Career Henan Chemical Co |
-
- Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)-
923289-36-5
- $1.00
- 95%-99%
- Career Henan Chemical Co
