1,3-phenyldiboronic acid, bis(pinacol) ester
- CAS No.
- 196212-27-8
- Chemical Name:
- 1,3-phenyldiboronic acid, bis(pinacol) ester
- Synonyms
- 1,3-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene;1,3-Phenyldiboronic acid;M7122;JACS-196212-27-8;1,3-Benzenediborate dipinacol ester;1,3-Phenyldiboronic acid, pinacol ester;1,3-Phenylenediboronic Acid Pinacol Ester;4,4,5,5-Tetramethyl-2-[3-(tetramethyl-1,3;1,3-phenyldiboronic acid, bis(picol) ester;1,3-Pinnayl bisphenyldiboronic acid ester,
- CBNumber:
- CB51486451
- Molecular Formula:
- C18H28B2O4
- Molecular Weight:
- 330.03
- MDL Number:
- MFCD09864185
- MOL File:
- 196212-27-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 133.0 to 137.0 °C |
|---|---|
| Boiling point | 430.9±28.0 °C(Predicted) |
| Density | 1.03±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | soluble in Methanol |
| form | powder to crystaline |
| color | White to Almost white |
| InChI | InChI=1S/C18H28B2O4/c1-15(2)16(3,4)22-19(21-15)13-10-9-11-14(12-13)20-23-17(5,6)18(7,8)24-20/h9-12H,1-8H3 |
| InChIKey | LLQQCDJVSYEQQQ-UHFFFAOYSA-N |
| SMILES | C1(B2OC(C)(C)C(C)(C)O2)=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1 |
| UNSPSC Code | 12352106 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| WGK Germany | WGK 3 |
| HS Code | 2931900090 |
| Storage Class | 11 - Combustible Solids |
1,3-phenyldiboronic acid, bis(pinacol) ester price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | BML00188 | 1,3-phenyldiboronic acid, bis(pinacol) ester AldrichCPR | 196212-27-8 | 1g | $191 | 2026-04-30 | Buy |
| TCI Chemical | B5070 | 1,3-Benzenediboronic Acid Bis(pinacol) Ester >98.0%(GC) | 196212-27-8 | 1g | $94 | 2026-04-30 | Buy |
| TCI Chemical | B5070 | 1,3-Benzenediboronic Acid Bis(pinacol) Ester >98.0%(GC) | 196212-27-8 | 5g | $279 | 2026-04-30 | Buy |
| Usbiological | 290912 | 4,4,5,5-tetraMethyl-2-[3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,2-dioxaborolane Asreported | 196212-27-8 | 500mg | $389 | 2026-06-03 | Buy |
| Usbiological | 290912 | 4,4,5,5-tetraMethyl-2-[3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,2-dioxaborolane Asreported | 196212-27-8 | 1g | $546 | 2026-06-03 | Buy |
1,3-phenyldiboronic acid, bis(pinacol) ester Chemical Properties, Uses, Production
Synthesis
108-36-1
73183-34-3
196212-27-8
1. 1,3-dibromobenzene (2.5 g, 10.6 mmol), bis(pinacolato)diboron (6.0 g, 23.5 mmol), Pd(dppf)2Cl2 (0.9 g, 1.2 mmol), and potassium acetate (7.1 g, 72.1 mmol) were added into a reaction flask under the protection of argon. 2. The reaction mixture was degassed with argon for three times, then heated to 85 °C under argon atmosphere and reacted for 18 h. 3. After completion of reaction, it was cooled to room temperature and filtered. 4. The filtrate was extracted with ethyl acetate and the organic phases were combined. 5. The reaction mixture was then heated to 85 °C under argon atmosphere for 18 h. 3. After completion of the reaction, the reaction mixture was cooled to room temperature and filtered. 4. The filtrate was extracted with ethyl acetate and the organic phases were combined. 5. The organic phases were washed with water and saturated saline in turn. 6. The washed organic phases were dried with anhydrous sodium sulfate, filtered, and concentrated. 7. The resultant residue was purified by column chromatography on silica gel using an eluent of 1:9 ethyl acetate/hexanes mixture. 8. The eluent was a 1:9 solvent mixture of ethyl acetate/hexane. 8. The target fraction was collected and concentrated to remove the solvent. 9. The product was recrystallized from a solvent mixture of dichloromethane/methanol to give pinacol ester of 1,3-bis(phenylene diboron) acid as an off-white solid (3.008 g, 86% yield). 10.
References
[1] New Journal of Chemistry, 2018, vol. 42, # 6, p. 4728 - 4734
[2] Patent: US2012/226046, 2012, A1. Location in patent: Page/Page column 18; 19
[3] Organic Letters, 2007, vol. 9, # 4, p. 559 - 562
[4] Angewandte Chemie - International Edition, 2016, vol. 55, # 37, p. 11247 - 11250
[5] Angew. Chem., 2016, vol. 128, # 37, p. 11413 - 11417,5
1,3-phenyldiboronic acid, bis(pinacol) ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou SuGuan Chemical Technology Co., Ltd. | 15958048562 | 2032153781@qq.com | China | 463 | 58 |
| Guangshu Material (Wuhan) Co., Ltd. | 15071066002 | solomlibo@163.com | China | 148 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9336 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
View Latest Price from 1,3-phenyldiboronic acid, bis(pinacol) ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 1,3-Phenyldiboronic acid, bis(pinacol) ester
196212-27-8
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2026-07-27 | 1,3-phenyldiboronic acid, bis(pinacol) ester
196212-27-8
|
1KG | 99% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2023-11-27 | 1,3-phenyldiboronic acid, bis(pinacol) ester
196212-27-8
|
1kg | 99.9% | 30000 Kg | Hebei Xinsheng New Material Technology Co., LTD. |
-
- 1,3-Phenyldiboronic acid, bis(pinacol) ester
196212-27-8
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 1,3-phenyldiboronic acid, bis(pinacol) ester
196212-27-8
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 1,3-phenyldiboronic acid, bis(pinacol) ester
196212-27-8
- 99.9%
- Hebei Xinsheng New Material Technology Co., LTD.
