Methyl 2-amino-5-methoxybenzoate
- CAS No.
- 2475-80-1
- Chemical Name:
- Methyl 2-amino-5-methoxybenzoate
- Synonyms
- Methyl 6-amino-m-anisate;Methyl 5-methoxyanthranilate;Methyl2-amino-5-methoxybenzoate,96%;2-Amino-5-methoxybenzoic acid methyl ester;Benzoic acid, 2-aMino-5-Methoxy-, Methyl ester
- CBNumber:
- CB51486729
- Molecular Formula:
- C9H11NO3
- Molecular Weight:
- 181.19
- MDL Number:
- MFCD09038482
- MOL File:
- 2475-80-1.mol
- MSDS File:
- SDS
| Melting point | 37-38℃ |
|---|---|
| Boiling point | 298.8±20.0 °C(Predicted) |
| Density | 1.179±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 2.70±0.10(Predicted) |
| Appearance | Light brown to brown Solid |
| Water Solubility | Slightly Soluble (1.1 g/L) (25°C) in water. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2922500090 | |||||||||
| NFPA 704 |
|
Methyl 2-amino-5-methoxybenzoate price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR912063 | Methyl 2-amino-5-methoxybenzoate >98% | 2475-80-1 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR912063 | Methyl 2-amino-5-methoxybenzoate >98% | 2475-80-1 | 25g | $73 | 2026-06-04 | Buy |
| Apolloscientific | OR912063 | Methyl 2-amino-5-methoxybenzoate >98% | 2475-80-1 | 100g | $273 | 2026-06-04 | Buy |
| Apolloscientific | OR912063 | Methyl 2-amino-5-methoxybenzoate >98% | 2475-80-1 | 500g | $1249 | 2026-06-04 | Buy |
| Synthonix | M50089 | Methyl 2-amino-5-methoxybenzoate 97% | 2475-80-1 | 1g | $25 | 2026-05-06 | Buy |
Methyl 2-amino-5-methoxybenzoate Chemical Properties, Uses, Production
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Synthesis
2327-45-9
2475-80-1
The general procedure for the synthesis of methyl 2-amino-5-methoxybenzoate from methyl 5-methoxy-2-nitrobenzoate was as follows: methyl 5-methoxy-2-nitrobenzoate (1.60 g, 7.58 mmol) was dissolved in ethyl acetate (14 mL), and 10% palladium-carbon catalyst (containing 50% water, 320 mg) was added. The reaction was stirred at 20-25°C for 3 hours under hydrogen atmosphere (0.25 MPa). Upon completion of the reaction, the palladium-carbon catalyst was removed by filtration and the solvent was removed by distillation under reduced pressure. The resulting crude product was purified by silica gel column chromatography with hexane/ethyl acetate (10:1 to 5:1) as eluent to afford methyl 2-amino-5-methoxybenzoate (1.29 g, 94% yield). The product was characterized by 1H-NMR (CDCl3), δ: 3.76 (3H, s), 3.88 (3H, s), 5.37 (2H, br), 6.63 (1H, d, J = 8.8 Hz), 6.95 (1H, dd, J = 8.8, 3.1 Hz), 7.35 (1H, d, J = 3.1 Hz).
References
[1] Patent: EP1724268, 2006, A1. Location in patent: Page/Page column 50
[2] Synlett, 2016, vol. 27, # 8, p. 1237 - 1240
[3] Patent: EP1844768, 2007, A1. Location in patent: Page/Page column 25
[4] Patent: CN106478548, 2017, A. Location in patent: Paragraph 0089; 0090; 0121; 0122; 0137; 0138
[5] Australian Journal of Chemistry, 1972, vol. 25, p. 2621 - 2629
Methyl 2-amino-5-methoxybenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| The future of Shanghai Industrial Co., Ltd. | 021-61552785 | sales@shshiji.com | China | 9531 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from Methyl 2-amino-5-methoxybenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-12 | METHYL 2-AMINO-5-METHOXYBENZOATE
2475-80-1
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- METHYL 2-AMINO-5-METHOXYBENZOATE
2475-80-1
- $1.00
- 99%
- Career Henan Chemical Co
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