Methyl 5-methoxy-2-nitrobenzoate
- CAS No.
- 2327-45-9
- Chemical Name:
- Methyl 5-methoxy-2-nitrobenzoate
- Synonyms
- 5-Methoxy-2-nitroMethylbenzoate;METHYL 5-METHOXY-2-NITROBENZOATE;Methyl5-methoxy-2-nitrobenzoate98%;Methyl 5-methoxy-2-nitrobenzoate 98%;5-Methoxy-2-nitro-benzoic acid methyl ester;Benzoic acid,5-Methoxy-2-nitro-, Methyl ester
- CBNumber:
- CB2142605
- Molecular Formula:
- C9H9NO5
- Molecular Weight:
- 211.17
- MDL Number:
- MFCD00662902
- MOL File:
- 2327-45-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 2918300090 |
Methyl 5-methoxy-2-nitrobenzoate price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR7411 | Methyl 5-methoxy-2-nitrobenzoate 98% | 2327-45-9 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR7411 | Methyl 5-methoxy-2-nitrobenzoate 98% | 2327-45-9 | 25g | $35 | 2026-06-04 | Buy |
| Apolloscientific | OR7411 | Methyl 5-methoxy-2-nitrobenzoate 98% | 2327-45-9 | 100g | $131 | 2026-06-04 | Buy |
| aablocks | AA002MNP | Methyl 5-methoxy-2-nitrobenzoate 98% | 2327-45-9 | 5g | $11 | 2026-05-28 | Buy |
| aablocks | AA002MNP | Methyl 5-methoxy-2-nitrobenzoate 98% | 2327-45-9 | 10g | $15 | 2026-05-28 | Buy |
Methyl 5-methoxy-2-nitrobenzoate Chemical Properties,Uses,Production
Description
Methyl 5-methoxy-2-nitrobenzoate is an important organic intermediate, commonly used in organic synthesis. This compound can be synthesized from 5-Hydroxy-2-nitrobenzoic acid.
Synthesis
67-56-1
1882-69-5
2327-45-9
To a pressure-resistant reaction flask was added 5-methoxy-2-nitrobenzoic acid (3.98 g, 20.0 mmol) and anhydrous methanol (10 mL). Concentrated sulfuric acid (150 μL) was added slowly and dropwise. The reaction vial was sealed and the reaction was stirred at 85 °C for 4 days. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to half the original volume. Ethyl acetate (25 mL) was added to dilute, and the organic phase was washed sequentially with water (25 mL), saturated aqueous sodium bicarbonate solution (2 × 25 mL), saturated saline (2 × 25 mL) and water (2 × 25 mL). The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford methyl 5-methoxy-2-nitrobenzoate as a yellow oil (3.57 g, 87% yield). Its nuclear magnetic resonance hydrogen spectrum (1H NMR, 300 MHz, CDCl3) data were as follows: δ 8.04 (d, J = 8.8 Hz, 1H, H-6), 7.04 (d, J = 2.3 Hz, 1H, H-3), 7.00 (dd, J = 8.8, 2.8 Hz, 1H, H-4), 3.93 (s, 3H, OCH3), 3.91 (s. 3H, OCH3). The nuclear magnetic resonance carbon spectrum (13C NMR, 75 MHz, CDCl3) data were as follows: δ 166.7, 163.5, 140.2, 131.4, 126.8, 115.9, 114.2, 56.4, 53.5. The obtained data are in agreement with the literature reports.
References
[1] Synlett, 2016, vol. 27, # 8, p. 1237 - 1240
[2] Patent: WO2005/121152, 2005, A1. Location in patent: Page/Page column 30
Methyl 5-methoxy-2-nitrobenzoate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Lastest Price from Methyl 5-methoxy-2-nitrobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-12 | METHYL 5-METHOXY-2-NITROBENZOATE
2327-45-9
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- METHYL 5-METHOXY-2-NITROBENZOATE
2327-45-9
- $1.00
- 99%
- Career Henan Chemical Co
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