2,6-Dichloropyrimidine-4-carbonyl chloride
- CAS No.
- 26830-94-4
- Chemical Name:
- 2,6-Dichloropyrimidine-4-carbonyl chloride
- Synonyms
- 2,4-Dichloropyrimidine-6-carbonyl chloride;4-Pyrimidinecarbonyl chloride, 2,6-dichloro-
- CBNumber:
- CB51489982
- Molecular Formula:
- C5HCl3N2O
- Molecular Weight:
- 211.43
- MDL Number:
- MFCD08444236
- MOL File:
- 26830-94-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H312-H314-H332 |
| Precautionary statements | P260-P261-P264-P270-P271-P280-P301+P312-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P321-P322-P330-P363-P405-P501 |
| HS Code | 2933599590 |
2,6-Dichloropyrimidine-4-carbonyl chloride price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | BBA83094 | 2,6-Dichloropyrimidine-4-carbonyl chloride | 26830-94-4 | 2.5g | $468.75 | 2026-06-04 | Buy |
| aablocks | AA00BII9 | 2，6-Dichloropyrimidine-4-carbonyl chloride 95% | 26830-94-4 | 100mg | $16 | 2026-05-28 | Buy |
| aablocks | AA00BII9 | 2，6-Dichloropyrimidine-4-carbonyl chloride 95% | 26830-94-4 | 250mg | $21 | 2026-05-28 | Buy |
| aablocks | AA00BII9 | 2，6-Dichloropyrimidine-4-carbonyl chloride 95% | 26830-94-4 | 1g | $56 | 2026-05-28 | Buy |
| Crysdot | CD11155941 | 2,6-Dichloropyrimidine-4-carbonyl chloride 95+% | 26830-94-4 | 1g | $108 | 2026-05-26 | Buy |
2,6-Dichloropyrimidine-4-carbonyl chloride Chemical Properties, Uses, Production
Uses
2,6-Dichloropyrimidine-4-carbonyl Chloride,
Synthesis
65-86-1
26830-94-4
General procedure for the synthesis of 2,6-dichloropyrimidine-4-carbonyl chloride from orotate monohydrate: 1. In a dry reaction flask, whey acid monohydrate (34.828 g, 200.0 mmol), phosphorus trichloride (100 mL, 1092 mmol) and N,N-dimethylformamide (20 drops) were added. 2. The reaction mixture was heated to 110 °C and the reaction was stirred at this temperature overnight. 3. After completion of the reaction, the mixture was cooled to room temperature. 4. Hexane (500 mL) was added to the cooled dark reaction mixture with vigorous stirring. 5. Separate the hexane layer and wash rapidly with deionized water (100 mL x 1) and saturated saline (100 mL x 1) in that order. 6. Dry the organic phase with anhydrous magnesium sulfate and filter to remove the desiccant. 7. The solvent was carefully evaporated under reduced pressure to afford 2,6-dichloropyrimidine-4-carbonyl chloride as a light yellow liquid (26.13 g, 123.6 mmol, 62% yield). Product characterization: 1H NMR (400 MHz, CDCl3) δ 7.93 (s, 1H).
References
[1] Patent: WO2013/30665, 2013, A1. Location in patent: Page/Page column 104; 105
[2] Patent: WO2013/72758, 2013, A1. Location in patent: Page/Page column 93
[3] Patent: WO2014/135955, 2014, A1. Location in patent: Paragraph 0311
[4] Patent: WO2015/31036, 2015, A1. Location in patent: Page/Page column 72; 73
[5] Patent: US2015/175569, 2015, A1. Location in patent: Paragraph 0321
2,6-Dichloropyrimidine-4-carbonyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Dichloropyrimidine-4-carbonyl chloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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