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2-Chloro-4-methoxy-6-methylpyrimidine

2-Chloro-4-methoxy-6-methylpyrimidine Structure
2-Chloro-4-methoxy-6-methylpyrimidine structure
CAS No.
22536-64-7
Chemical Name:
2-Chloro-4-methoxy-6-methylpyrimidine
Synonyms
2-Chloro-4-methyl-6-methoxypyrimidine;PyriMidine,2-chloro-4-Methoxy-6-Methyl-;2-Chloro-4-methoxy-6-methylpyrimidine ISO 9001：2015 REACH
CBNumber:
CB51501299
Molecular Formula:
C6H7ClN2O
Molecular Weight:
158.59
MDL Number:
MFCD08689881
MOL File:
22536-64-7.mol
MSDS File:
SDS
Last updated:2026-05-28 02:06:17
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2-Chloro-4-methoxy-6-methylpyrimidine Properties

Melting point 22-25℃
Boiling point 268℃
Density 1.237
Flash point 116℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H350
Precautionary statements  P201-P301+P310-P308+P313
HS Code  2933599590

2-Chloro-4-methoxy-6-methylpyrimidine price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR943132 2-Chloro-4-methoxy-6-methylpyrimidine 97% 22536-64-7 100mg $21 2026-06-04 Buy
Apolloscientific OR943132 2-Chloro-4-methoxy-6-methylpyrimidine 97% 22536-64-7 250mg $30 2026-06-04 Buy
Apolloscientific OR943132 2-Chloro-4-methoxy-6-methylpyrimidine 97% 22536-64-7 1g $56 2026-06-04 Buy
Apolloscientific OR943132 2-Chloro-4-methoxy-6-methylpyrimidine 97% 22536-64-7 5g $184 2026-06-04 Buy
Apolloscientific OR943132 2-Chloro-4-methoxy-6-methylpyrimidine 97% 22536-64-7 25g $588 2026-06-04 Buy
Product number Packaging Price Buy
OR943132 100mg $21 Buy
OR943132 250mg $30 Buy
OR943132 1g $56 Buy
OR943132 5g $184 Buy
OR943132 25g $588 Buy

2-Chloro-4-methoxy-6-methylpyrimidine Chemical Properties, Uses, Production

Synthesis

2-Amino-4-methoxy-6-methylpyrimidine

7749-47-5

2-Chloro-4-methoxy-6-methylpyrimidine

22536-64-7

General procedure for the synthesis of 2-chloro-4-methoxy-6-methylpyrimidine from 2-amino-4-methoxy-6-methylpyrimidine: 2-amino-4-methoxy-6-methylpyrimidine (5 g, 35.97 mmol) was dissolved in concentrated hydrochloric acid (50 ml), and aqueous (5 ml) solution of sodium nitrite (2.97 g, 43.16 mmol) was slowly added dropwise. The reaction was maintained at 0°C for 30 min followed by stirring at room temperature for 1 hr. After completion of the reaction, the reaction was quenched with 10N sodium hydroxide solution and the insoluble material was removed by filtration. The filtrate was subjected to liquid-liquid partitioning with ethyl acetate (AcOEt) and saturated saline, and the aqueous layer was then extracted with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to give a brown oily crude product. The crude product was purified by fast column chromatography (silica gel: 100-200 mesh, eluent: ethyl acetate-petroleum ether; 10:90→15:85) to obtain 600 mg (8% yield) of white solid, which was the target compound 2-chloro-4-methoxy-6-methylpyrimidine.

References

[1] Patent: WO2017/191599, 2017, A1. Location in patent: Page/Page column 176; 177
[2] Yakugaku Zasshi, 1953, vol. 73, p. 598,600
[3] Chem.Abstr., 1954, p. 9362
[4] Bulletin des Societes Chimiques Belges, 1959, vol. 68, p. 30,55
[5] Patent: US4496392, 1985, A

2-Chloro-4-methoxy-6-methylpyrimidine Preparation Products And Raw materials

Raw materials

2-Amino-4-methoxy-6-methylpyrimidine 2,4-Dichloro-6-methylpyrimidine Sodium Methoxide Hydrochloric acid Sodium nitrite

Preparation Products

2-Diethylamino-6-hydroxy-4-methylpyrimidine 2-hydrazino-4-methoxy-6-methyl-pyrimidine

2-Chloro-4-methoxy-6-methylpyrimidine Suppliers

Global Suppliers ( 85)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Nanjing Vital Chemical Co., Ltd. Please Send Email 18652950785 chemweiao@163.com China 4368 65
Amber MolTech LLC 086-010-62176588 amber@jyamber.com China 10150 56
Shanghai Synthfine Chemical Co.,Ltd 15921303235 sales@synthfine.com China 995 58
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3996 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Supplier Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Accela ChemBio Co.,Ltd. 64
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Nanjing Vital Chemical Co., Ltd. 65
Amber MolTech LLC 56
Shanghai Synthfine Chemical Co.,Ltd 58
Chiba Pharmaceutical Science and technology Co, Ltd. 55
SynAsst Chemical. 55
Shanghai Raise Chemical Technology Co.,Ltd 55

View Latest Price from 2-Chloro-4-methoxy-6-methylpyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-4-methoxy-6-methylpyrimidine pictures 2026-08-20 2-Chloro-4-methoxy-6-methylpyrimidine
22536-64-7
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited

2-Chloro-4-methoxy-6-methylpyrimidine Spectrum

2-Chloro-4-methoxy-6-methylpyrimidine(22536-64-7)1HNMR

22536-64-7 (2-Chloro-4-methoxy-6-methylpyrimidine) Related Search:

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2-Chloro-4-methyl-6-methoxypyrimidine PyriMidine,2-chloro-4-Methoxy-6-Methyl- 2-Chloro-4-methoxy-6-methylpyrimidine ISO 9001：2015 REACH 22536-64-7 pharmacetical