2,8-DIAZASPIRO[4.5]DECAN-3-ONE
![2,8-DIAZASPIRO[4.5]DECAN-3-ONE Structure](CAS2/GIF/561314-57-6.gif)
- CAS No.
- 561314-57-6
- Chemical Name:
- 2,8-DIAZASPIRO[4.5]DECAN-3-ONE
- Synonyms
- 2,8-Diazaspiro[4.5]decan-...;2,8-DIAZASPIRO[4.5]DECAN-3-ONE;3,8-Diazaspiro[4.5]decan-2-one HCl;2,8-Diazaspiro[4.5]decan-3-one 95+%;2,8-Diazaspiro[4.5]decan-3-one - [D6100];2,8-Diazaspiro[4.5]decan-3-one (9CI, ACI);2,8-diazaspiro[4.5]decan-3-one(SALTDATA: 2HCl)
- CBNumber:
- CB51516808
- Molecular Formula:
- C8H14N2O
- Molecular Weight:
- 154.21
- MDL Number:
- MFCD11044206
- MOL File:
- 561314-57-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,8-Diazaspiro[4.5]decan-3-one | 299587 | 250.00mg | $76 |
| 2,8-Diazaspiro[4.5]decan-3-one | 299587 | 1.00g | $106 |
| 2,8-Diazaspiro[4.5]decan-3-one | 299587 | 5.00g | $315 |
| 2,8-Diazaspiro[4.5]decan-3-one 97.0% | D6100 | 100mg | $43 |
| 2,8-Diazaspiro[4.5]decan-3-one 97.0% | D6100 | 250mg | $74 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H332-H315-H319-H335 |
| Precautionary statements | P271-P260-P280 |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36 |
| HS Code | 29339900 |
2,8-DIAZASPIRO[4.5]DECAN-3-ONE price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 299587 | 2,8-Diazaspiro[4.5]decan-3-one | 561314-57-6 | 250.00mg | $76 | 2026-05-19 | Buy |
| Matrix Scientific | 299587 | 2,8-Diazaspiro[4.5]decan-3-one | 561314-57-6 | 1.00g | $106 | 2026-05-19 | Buy |
| Matrix Scientific | 299587 | 2,8-Diazaspiro[4.5]decan-3-one | 561314-57-6 | 5.00g | $315 | 2026-05-19 | Buy |
| Synthonix | D6100 | 2,8-Diazaspiro[4.5]decan-3-one 97.0% | 561314-57-6 | 100mg | $43 | 2026-05-06 | Buy |
| Synthonix | D6100 | 2,8-Diazaspiro[4.5]decan-3-one 97.0% | 561314-57-6 | 250mg | $74 | 2026-05-06 | Buy |
2,8-DIAZASPIRO[4.5]DECAN-3-ONE Chemical Properties,Uses,Production
Chemical Properties
White powder
Synthesis
![TERT-BUTYL 3-OXO-2,8-DIAZASPIRO[4.5]DECANE-8-CARBOXYLATE](/CAS/GIF/169206-67-1.gif)
169206-67-1
![2,8-DIAZASPIRO[4.5]DECAN-3-ONE](/CAS2/GIF/561314-57-6.gif)
561314-57-6
Tert-butyl 3-oxo-2,8-diazaspiro[4,5]decane-8-carboxylate (920 mg, 3.62 mmol) was used as a raw material and dissolved in a solvent mixture (5 mL / 5 mL) of dichloromethane (DCM) and trifluoroacetic acid (TFA). The reaction mixture was stirred at 30 °C for 12 hours. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio of petroleum ether: ethyl acetate = 1:1) to confirm that the reaction was complete. After completion of the reaction, the mixture was concentrated under reduced pressure to give the crude product. The crude product was dissolved in water (30 mL) and the pH was adjusted to 10 with 1N sodium hydroxide solution. subsequently, extraction was performed with dichloromethane (15 mL x 4). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to afford the target compound 2,8-diazaspiro[4.5]decan-3-one (550 mg, 98% yield) as a yellow oil.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 10, p. 2288 - 2294
[2] Patent: CN105330698, 2016, A. Location in patent: Paragraph 0232; 0233; 0234; 0235
2,8-DIAZASPIRO[4.5]DECAN-3-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3861 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | chem1022@hengdian-group.com | China | 1478 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| Nanjing Yushan Wanfang Biotechnology Co., Ltd. | +86-025-84918180 +86-18014482516 | 3552541679@qq.com | China | 995 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
View Lastest Price from 2,8-DIAZASPIRO[4.5]DECAN-3-ONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![2,8-DIAZASPIRO[4.5]DECAN-3-ONE pictures](https://img.chemicalbook.com/ProductImageEN/2019-12/Small/edc07623-0c0a-4284-9e9a-5e802c130fe6.jpg) |
2019-12-24 | 2,8-DIAZASPIRO[4.5]DECAN-3-ONE
61314-57-6
|
$1.00 | 100g | 98%min | Career Henan Chemical Co | ||
![2,8-DIAZASPIRO[4.5]DECAN-3-ONE pictures](https://img.chemicalbook.com/ProductImageEN/2019-12/Small/fce30fef-e4e5-4a8a-b38b-d2742f74525c.png) |
2019-12-24 | 2,8-DIAZASPIRO[4.5]DECAN-3-ONE
561314-57-6
|
$1.00 | 100g | 98%min | Career Henan Chemical Co |
-
- 2,8-DIAZASPIRO[4.5]DECAN-3-ONE
61314-57-6
- $1.00
- 98%min
- Career Henan Chemical Co
-
- 2,8-DIAZASPIRO[4.5]DECAN-3-ONE
561314-57-6
- $1.00
- 98%min
- Career Henan Chemical Co
