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7-Chloropyrazolo[1,5-a]pyrimidine

7-Chloropyrazolo[1,5-a]pyrimidine Structure
7-Chloropyrazolo[1,5-a]pyrimidine structure
CAS No.
58347-49-2
Chemical Name:
7-Chloropyrazolo[1,5-a]pyrimidine
Synonyms
7-Chloropyrazolo[1,5-a]pyrimidine;Pyrazolo[1,5-a]pyrimidine, 7-chloro-
CBNumber:
CB51517825
Molecular Formula:
C6H4ClN3
Molecular Weight:
153.57
MDL Number:
MFCD04035684
MOL File:
58347-49-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:12
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7-Chloropyrazolo[1,5-a]pyrimidine Properties

Melting point 96-98℃
Density 1.51
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Powder
pka -0.59±0.40(Predicted)
color Off-white to yellow to pink to brown
InChI InChI=1S/C6H4ClN3/c7-5-1-3-8-6-2-4-9-10(5)6/h1-4H
InChIKey YCZQHXPIKQHABJ-UHFFFAOYSA-N
SMILES C12=CC=NN1C(Cl)=CC=N2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P264-P270-P301+P312-P330-P501
HS Code  2933998090

7-Chloropyrazolo[1,5-a]pyrimidine price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 295673 7-Chloropyrazolo[1,5-a]pyrimidine Asreported 58347-49-2 100mg $369 2026-06-03 Buy
Usbiological 295673 7-Chloropyrazolo[1,5-a]pyrimidine Asreported 58347-49-2 250mg $456 2026-06-03 Buy
Usbiological 295673 7-Chloropyrazolo[1,5-a]pyrimidine Asreported 58347-49-2 500mg $609 2026-06-03 Buy
Usbiological 295673 7-Chloropyrazolo[1,5-a]pyrimidine Asreported 58347-49-2 1g $814 2026-06-03 Buy
AstaTech SC3201 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE 95% 58347-49-2 1G $65 2026-04-30 Buy
Product number Packaging Price Buy
295673 100mg $369 Buy
295673 250mg $456 Buy
295673 500mg $609 Buy
295673 1g $814 Buy
SC3201 1G $65 Buy

7-Chloropyrazolo[1,5-a]pyrimidine Chemical Properties, Uses, Production

Uses

7-Clopizo[1,5-A]pyrimidine is a heterocyclic organic compound that can be used as an organic intermediate.

Synthesis

4H-PYRAZOLO[1,5-A]PYRIMIDIN-7-ONE

29274-23-5

7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE

58347-49-2

Pyrazolo[1,5-a]pyrimidin-7(4H)-one (0.50 g, 3.70 mmol) was added with phosphorus trichloride (0.88 mL, 9.62 mmol) and diisopropylethylamine (DIEA, 0.13 mL, 0.74 mmol), mixed well and then the reaction was stirred at 90 °C overnight. After completion of the reaction, the reaction mixture was slowly poured into ice water and extracted with dichloromethane, and the extract was washed with brine. The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated in vacuum. The crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 9:1) to afford the target compound 7-chloropyrazolo[1,5-a]pyrimidine (83 mg, 71% yield).LRMS (m/z): 154 (M + 1)+.1H NMR (400 MHz, DMSO-d6) δ ppm: 6.93 (d, 1H), 7.43 (d, 1H), 8.37 (d, 1H), 8.37 (d, 1H). 1H), 8.37 (d, 1H), 8.52 (d, 1H).

References

[1] Patent: EP2518071, 2012, A1. Location in patent: Page/Page column 38
[2] Patent: WO2012/146667, 2012, A1. Location in patent: Page/Page column 90
[3] Patent: WO2012/146666, 2012, A1. Location in patent: Page/Page column 160
[4] Patent: WO2007/17678, 2007, A1. Location in patent: Page/Page column 44
[5] Journal of Medicinal Chemistry, 1981, vol. 24, # 5, p. 610 - 613

7-Chloropyrazolo[1,5-a]pyrimidine Preparation Products And Raw materials

Raw materials

4H-Pyrazolo[1,5-a]pyrimidin-7-one

Preparation Products

7-Chloropyrazolo[1,5-a]pyrimidine Suppliers

Global Suppliers ( 134)
Supplier Tel Email Country ProdList Advantage
Shanghai Synthfine Chemical Co.,Ltd 15921303235 sales@synthfine.com China 995 58
Shaoyuan Technology (Shanghai) Co., Ltd. 021-50795510 4000665055 marketing@accelachem.com China 9985 58
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
China Langchem Inc. 0086-21-58956006 China 7798 57
Supplier Advantage
Shanghai Synthfine Chemical Co.,Ltd 58
Shaoyuan Technology (Shanghai) Co., Ltd. 58
Nanbu County Chengxin Technology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Ark Pharm, Inc. 56
Beijing Ouhe Technology Co., Ltd 60
Pure Chemistry Scientific Inc. 62
Chemsky（shanghai）International Co.,Ltd. 50
China Langchem Inc. 57

View Latest Price from 7-Chloropyrazolo[1,5-a]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-Chloropyrazolo[1,5-a]pyriMidine pictures 2020-05-17 7-Chloropyrazolo[1,5-a]pyriMidine
58347-49-2
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE pictures 2019-07-06 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE
58347-49-2
 $1.00 1KG 95% 500kg Career Henan Chemical Co

7-Chloropyrazolo[1,5-a]pyrimidine Spectrum

7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE(58347-49-2)1HNMR

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Pyrazolo[1,5-a]pyrimidine, 7-chloro- 7-Chloropyrazolo[1,5-a]pyrimidine 58347-49-2 Heterocycle-Pyrimidine series