2-(6-bromopyridin-2-yl)acetic acid
- CAS No.
- 1093879-46-9
- Chemical Name:
- 2-(6-bromopyridin-2-yl)acetic acid
- Synonyms
- 6-BroMo-2-pyridineacetic acid;2-Pyridineacetic acid, 6-bromo-;2-(6-bromo-2-pyridyl)acetic acid;2-(6-bromopyridin-2-yl)acetic acid
- CBNumber:
- CB51557216
- Molecular Formula:
- C7H6BrNO2
- Molecular Weight:
- 216.03
- MDL Number:
- MFCD10000075
- MOL File:
- 1093879-46-9.mol
| Product description | Number | Pack Size | Price |
| 2-(6-Bromopyridin-2-yl)acetic acid ≥95% | OR52749 | 250mg | $25 |
| 2-(6-Bromopyridin-2-yl)acetic acid ≥95% | OR52749 | 1g | $86 |
| 2-(6-Bromopyridin-2-yl)acetic acid ≥95% | OR52749 | 5g | $357 |
| 2-(6-Bromopyridin-2-yl)acetic acid | 306407 | 250.00mg | $25 |
| 2-(6-Bromopyridin-2-yl)acetic acid | 306407 | 1.00g | $74 |
| More product size | |||
| Boiling point | 347.2±27.0 °C(Predicted) |
|---|---|
| Density | 1.710±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 3.76±0.10(Predicted) |
| Appearance | Off-white to light brown Solid |
| InChI | InChI=1S/C7H6BrNO2/c8-6-3-1-2-5(9-6)4-7(10)11/h1-3H,4H2,(H,10,11) |
| InChIKey | XZQWPHKCEJPCDK-UHFFFAOYSA-N |
| SMILES | C1(CC(O)=O)=NC(Br)=CC=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
2-(6-bromopyridin-2-yl)acetic acid price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR52749 | 2-(6-Bromopyridin-2-yl)acetic acid ≥95% | 1093879-46-9 | 250mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | OR52749 | 2-(6-Bromopyridin-2-yl)acetic acid ≥95% | 1093879-46-9 | 1g | $86 | 2026-06-04 | Buy |
| Apolloscientific | OR52749 | 2-(6-Bromopyridin-2-yl)acetic acid ≥95% | 1093879-46-9 | 5g | $357 | 2026-06-04 | Buy |
| Matrix Scientific | 306407 | 2-(6-Bromopyridin-2-yl)acetic acid | 1093879-46-9 | 250.00mg | $25 | 2026-05-19 | Buy |
| Matrix Scientific | 306407 | 2-(6-Bromopyridin-2-yl)acetic acid | 1093879-46-9 | 1.00g | $74 | 2026-05-19 | Buy |
2-(6-bromopyridin-2-yl)acetic acid Chemical Properties,Uses,Production
Uses
6-Bromo-2-pyridineacetic Acid is used in preparation of pyrimidine derivatives as RORγ modulators.
Synthesis
955369-63-8
1093879-46-9
The general procedure for the synthesis of 2-bromo-6-pyridylacetic acid from ethyl (6-bromopyridin-2-yl)acetate was as follows: to a mixed solution of THF (10 mL), water (10 mL), and MeOH (20 mL) containing ethyl 2-(6-bromo-2-pyridinyl)acetate (2.00 g, 8.19 mmol) was added LiOH-H2O (1.03 g, 24.5 mmol). Subsequently, the reaction mixture was stirred at 20 °C for 2 hours. After completion of the reaction, the mixture was concentrated in vacuum. The residue was acidified with 1.0 N HCl to pH=3.0, washed with water (150 mL) and extracted with ethyl acetate (3 x 150 mL). The organic layers were combined, dried with Na2SO4, filtered and concentrated in vacuum to give 2-bromo-6-pyridineacetic acid (1.70 g, 96% yield) as a light yellow solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ=12.63 (br.s, 1H), 7.86-7.71 (m, 1H), 7.59 (d, J=8.0 Hz, 1H), 7.46 (d, J=7.6 Hz, 1H), 3.81 (s, 2H).
References
[1] Patent: WO2018/106636, 2018, A1. Location in patent: Paragraph 00239
[2] Journal of Organic Chemistry, 2018, vol. 83, # 16, p. 9088 - 9095
2-(6-bromopyridin-2-yl)acetic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +86-13382787392 | sales@aeechem.com | China | 10002 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Xi 'an fanta biotechnology co., LTD | 19929974101 //1144079830; 19929974101 | 1144079830@qq.com | China | 956 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9850 | 55 |
