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TANDUTINIB
- CAS No.
- 228266-40-8
- Chemical Name:
- TANDUTINIB
- Synonyms
- Taltobulin;Spa 110;Hti 286;CS-1371;Unii-J6D6912bxs;HTI-286;SPA-110;Taltobulin (HTI-286);HTI-286 hydrochloride;SPA-110 hydrochloride;HTI-286 HYDROCHLORIDE;SPA-110 HYDROCHLORIDE
- CBNumber:
- CB52131222
- Molecular Formula:
- C27H43N3O4
- Molecular Weight:
- 473.66
- MDL Number:
- MFCD07772353
- MOL File:
- 228266-40-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-29 13:23:30
| Product description | Number | Pack Size | Price |
| HTI 286 ≥98% | 32852 | 1mg | $63 |
| HTI 286 ≥98% | 32852 | 5mg | $257 |
| Taltobulin | DJA26640 | 2mg | $188.46 |
| Taltobulin | DJA26640 | 5mg | $344.7 |
| Taltobulin | DJA26640 | 10mg | $659.6 |
| More product size | |||
| Melting point | 135-137 ºC |
|---|---|
| Boiling point | 662.4±55.0 °C(Predicted) |
| Density | 1.063 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO: 40 mg/ml |
| form | A solid |
| pka | 4.68±0.19(Predicted) |
| color | White to off-white |
| FDA UNII | J6D6912BXS |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| NFPA 704 |
|
TANDUTINIB price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 32852 | HTI 286 ≥98% | 228266-40-8 | 1mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 32852 | HTI 286 ≥98% | 228266-40-8 | 5mg | $257 | 2026-04-30 | Buy |
| Biosynth | DJA26640 | Taltobulin | 228266-40-8 | 2mg | $188.46 | 2026-06-04 | Buy |
| Biosynth | DJA26640 | Taltobulin | 228266-40-8 | 5mg | $344.7 | 2026-06-04 | Buy |
| Biosynth | DJA26640 | Taltobulin | 228266-40-8 | 10mg | $659.6 | 2026-06-04 | Buy |
TANDUTINIB Chemical Properties,Uses,Production
Uses
Treatment of solid tumors.
in vivo
Taltobulin (HTI-286; 1.6 mg/kg i.v.) inhibits the growth of human tumor xenografts (e.g., HCT-15, DLD-1, MX-1W, and KB-8-5) in athymic nu/nu female mice[1].
Taltobulin (HTI-286; 3 mg/kg; p.o. gavage) inhibits growth by 97.3 % and 82% in athymic nu/nu female mice with Lox melanoma xenografts and KB-3-1 epidermoid xenograft model, respectively[1].
| Animal Model: | Athymic nu/nu female mice with Lox melanoma model (5-6 weeks of age)[1] |
| Dosage: | 1.6 mg/kg |
| Administration: | Administered i.v.;for 35 days |
| Result: | Growth of Lox tumors was inhibited by 96-98% on day 12 compared with vehicle-treated controls. Growth of KB-8-5 tumors was inhibited by 84% on day 14 compared with vehicle-treated controls. Growth of MX-1W tumors was inhibited by 97% compared with vehicle-treated controls. Growth of DLD-1 and HCT-15 tumors was inhibited by 80 and 66%, respectively. |
IC 50
Traditional Cytotoxic Agents
TANDUTINIB Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 79)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Adachibio Inc. | +81-8027837258; | sales@adachibio.com | Japan | 938 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9037 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| ChemExpress | +86-19370970350 +86-021-58950125 | info@chemexpress.com | China | 790 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Shaanxi Dideu New Materials Co. Ltd | 18192503167 | 1036@dideu.com | China | 13220 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Henan Rane Chemical Co., Ltd. | +86-18738066252 | info@ranechem.com | China | 3000 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4857 | 55 |
View Lastest Price from TANDUTINIB manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-29 | TANDUTINIB
228266-40-8
|
1KG | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-07-13 | Taltobulin
228266-40-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-09 | Taltobulin
228266-40-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- TANDUTINIB
228266-40-8
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Taltobulin
228266-40-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Taltobulin
228266-40-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
CS-1371
N,beta,beta-Trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-butenyl]-N,3-dimethyl-L-valinamide
Hti 286
L-Valinamide, N,beta,beta-trimethyl-L-phenylalanyl-N-((1S,2E)-3-carboxy-1-(1-methylethyl)-2-butenyl)-N,3-dimethyl-
Spa 110
Unii-J6D6912bxs
N,β,β-Trimethyl-L-phenylalanyl-N-[(3S,4E)-5-carboxy-2-methyl-4-hexen-3-yl]-N,3-dimethyl-L-valinamide
Taltobulin (HTI-286)
HTI-286;SPA-110
HTI-286 hydrochloride
HTI-286 HYDROCHLORIDE;SPA-110 HYDROCHLORIDE
SPA-110 hydrochloride
L-Valinamide, N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-buten-1-yl]-N,3-dimethyl-
L-Valinamide,N,b,b-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-butenyl]-N,3-dimethyl-
(S,E)-2,5-Dimethyl-4-((S)-N,3,3-trimethyl-2-((S)-3-methyl-2-(methylamino)-3-phenylbutanamido)butanamido)hex-2-enoic acid
(2E,4S)-2,5-dimethyl-4-[(2S)-N,3,3-trimethyl-2-[(2S)-3-methyl-2-(methylamino)-3-phenylbutanamido]butanamido]hex-2-enoic acid
Taltobulin
228266-40-8
C27H43N3O4
