4-Aminodiphenylamine
- CAS No.
- 101-54-2
- Chemical Name:
- 4-Aminodiphenylamine
- Synonyms
- 4-ADPA;N-PHENYL-P-PHENYLENEDIAMINE;P-AMINODIPHENYLAMINE;N1-phenylbenzene-1,4-diamine;4-N-phenylbenzene-1,4-diamine;VARIAMINE BLUE RT;Variamine Blue RT Base;N-Phenyl-1,4-benzenediamine;N-PHENYL-1,4-PHENYLENEDIAMINE;UBOB
- CBNumber:
- CB9418967
- Molecular Formula:
- C12H12N2
- Molecular Weight:
- 184.24
- MDL Number:
- MFCD00007850
- MOL File:
- 101-54-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 69 °C |
|---|---|
| Boiling point | 354 °C |
| Density | 1.09 |
| vapor pressure | 1 hPa |
| refractive index | 1.6266 (estimate) |
| Flash point | 193°C |
| storage temp. | Store below +30°C. |
| solubility | ethanol: soluble10mg/mL, clear, very dark red (Violet to brown to black solution) |
| pka | 5.20±0.10(Predicted) |
| form | Liquid |
| Colour Index | 37240 |
| color | Clear |
| PH | 8.9 (0.5g/l, H2O, 20℃) |
| Water Solubility | Soluble in water at 20°C 0.6g/L. Soluble in (10 mg/mL) ethanol. |
| BRN | 908935 |
| Henry's Law Constant | 1.5×103 mol/(m3Pa) at 25℃, Yaws (2003) |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, plastics. |
| Cosmetics Ingredients Functions | HAIR DYEING |
| Cosmetic Ingredient Review (CIR) | 4-Aminodiphenylamine (101-54-2) |
| InChI | 1S/C12H12N2/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9,14H,13H2 |
| InChIKey | ATGUVEKSASEFFO-UHFFFAOYSA-N |
| SMILES | Nc1ccc(Nc2ccccc2)cc1 |
| LogP | 1.82 at 20℃ and pH7 |
| Dissociation constant | 5.45-5.47 at 20℃ |
| Toxicology and Carcinogenesis | Bioassay of N-Phenyl-p-phenylenediamine for Possible Carcinogenicity (CASRN 101-54-2) |
| CAS DataBase Reference | 101-54-2(CAS DataBase Reference) |
| EWG's Food Scores | 3-7 |
| FDA UNII | 007X4XXS71 |
| NIST Chemistry Reference | 1,4-Benzenediamine, N-phenyl-(101-54-2) |
| EPA Substance Registry System | p-Aminodiphenylamine (101-54-2) |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H317-H410 | |||||||||
| Precautionary statements | P501-P261-P273-P272-P270-P264-P280-P302+P352-P391-P337+P313-P305+P351+P338-P362+P364-P333+P313-P301+P312+P330 | |||||||||
| Hazard Codes | Xn,Xi,N | |||||||||
| Risk Statements | 22-36-43-42/43-36/37/38-20/22-50/53 | |||||||||
| Safety Statements | 26-36-45-36/37/39-61-60-36/37 | |||||||||
| RIDADR | UN3077 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | ST3150000 | |||||||||
| F | 8 | |||||||||
| Autoignition Temperature | >500 °C | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29215990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 Eye Irrit. 2 Skin Sens. 1 |
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| Hazardous Substances Data | 101-54-2(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: 464 mg/kg LD50 dermal Rabbit > 5000 mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
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4-Aminodiphenylamine price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 241393 | N-Phenyl-p-phenylenediamine 98% | 101-54-2 | 100g | $56.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 241393 | N-Phenyl-p-phenylenediamine 98% | 101-54-2 | 1kg | $215 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.14648 | 4-Aminodiphenylamine for synthesis | 101-54-2 | 100g | $34.1 | 2022-05-15 | Buy |
| Sigma-Aldrich | 8.14648 | 4-Aminodiphenylamine for synthesis | 101-54-2 | 1kg | $141 | 2022-05-15 | Buy |
| TCI Chemical | P0203 | Azoic Diazo Component 22 >98.0%(HPLC)(T) | 101-54-2 | 25g | $19 | 2026-04-30 | Buy |
4-Aminodiphenylamine Chemical Properties, Uses, Production
Description
p-Aminodiphenylamine hydrochloride was formerly used as a hair dye. Sensitization, when deteeted by patch testing, is relatively low in hairdressers.
Chemical Properties
Dark grey flake
Uses
Dye intermediate, pharmaceuticals, photographic chemicals.
Uses
4-Aminodiphenylamine is used as an oxidation dye color in hair dyes. It is also promoted as an efficient reagent for oxidase enzymes, including glucose, lactate, xanthine, and lysine oxidases.
Uses
p-Anilinoaniline is an antioxidant that has shown to cause a reduction of NOx emissions from soybean biodiesel powered DI diesel engines but has increased CO and HC emissions. It is also used to produce dyes, pharmaceuticals, and photographic chemicals and frmerly used as a hair dye.
Definition
ChEBI: An aromatic amine that is the 4-amino derivative of diphenylamine.
General Description
Odorless purple-black solid or flake or dark purple chips.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
4-Aminodiphenylamine is incompatible with strong oxidizers. 4-Aminodiphenylamine is also incompatible with strong acids. 4-Aminodiphenylamine may react with plastics.
Fire Hazard
4-Aminodiphenylamine is combustible.
Contact allergens
This substance was formerly used as a hair dye. Sensitization, when detected by patch testing, is relatively low in hairdressers.
Purification Methods
It crystallises from EtOH with m 66o, and from ligroin with m 75o. It can be distilled at high vacuum. [Beilstein 13 IV 113.]
4-Aminodiphenylamine Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zibo tailize Chemical Co. , Ltd. | 0533-5200592 13173271895 | 283531267@qq.com | China | 24 | 58 |
| Dexin chemical (Shandong) Co. , Ltd. | 15853369661 | 1092794701@qq.com | China | 159 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Beckmann-Kenko GmbH | +49 4241 9308 88 | info@beckmann-kenko.com | Germany | 478 | 62 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from 4-Aminodiphenylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 4-Aminodiphenylamine
101-54-2
|
$70.00 | 10kg | 99 % | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | 4-Aminodiphenylamine
101-54-2
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-08-20 | 4-Aminodiphenylamine
101-54-2
|
$40.00 | 1KG | 99 | 10 tons | Shijiazhuang tongyang Import and Export Co., LTD |
-
- 4-Aminodiphenylamine
101-54-2
- $70.00
- 99 %
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 4-Aminodiphenylamine
101-54-2
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-Aminodiphenylamine
101-54-2
- $40.00
- 99
- Shijiazhuang tongyang Import and Export Co., LTD
