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AF-DX 384

AF-DX 384 structure

CAS No.: 118290-27-0

Chemical Name:: AF-DX 384

Synonyms: AF-DX 384;AF-DX 384 methanesulfonate;AF-DX 384, M2/M4 antagonist;N-(2-(2-((DIPROPYLAMINO)METHYL)PIPERIDIN-1-YL)ETHYL)-6-OXO-5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPINE-11(6H)-CARBOXAMIDE;N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxami;N-[2-[2-[(DIPROPYLAMINO)METHYL]-1-PIPERIDINYL]ETHYL]-5,6-DIHYDRO-6-OXO-11H-PYRIDO[2,3-B][1,4]BENZODIAZEPINE-11-CARBOXAMIDE;11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-, methanesulfonate (1:1)

CBNumber:: CB5218693

Molecular Formula:: C27H38N6O2.CH4O3S

Molecular Weight:: 574.74

MDL Number:: MFCD00884624

MOL File:: 118290-27-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-11 19:39:08

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AF-DX 384 Properties

storage temp.	Store at RT

AF-DX 384 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA0034CY	11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-, methanesulfonate (1:1) >95%	118290-27-0	10mg	$255	2026-05-28	Buy
aablocks	AA0034CY	11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-, methanesulfonate (1:1) >95%	118290-27-0	50mg	$849	2026-05-28	Buy
Crysdot	CD11339444	AFDX384 95+%	118290-27-0	25mg	$408	2026-05-27	Buy
Tocris	1345	AF-DX384 ≥98%(HPLC)	118290-27-0	10	$159	2021-12-16	Buy
Tocris	1345	AF-DX384 ≥98%(HPLC)	118290-27-0	50	$647	2021-12-16	Buy

Product number	Packaging	Price	Buy
AA0034CY	10mg	$255	Buy
AA0034CY	50mg	$849	Buy
CD11339444	25mg	$408	Buy
1345	10	$159	Buy
1345	50	$647	Buy

AF-DX 384 Chemical Properties,Uses,Production

Uses

AF-DX 384 is a potent mAChR M2/mAChR M4selective antagonist.

Definition

ChEBI: N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide is a benzodiazepine.

Biological Activity

Potent M 2 /M 4 selective antagonist (pK i values are 8.22, 8.00, 7.51, 7.18 and 6.27 at human M 2 , M 4 , M 1 , M 3 and M 5 receptors respectively).

AF-DX 384 Preparation Products And Raw materials

Raw materials

Preparation Products

AF-DX 384 Suppliers

Global( 40)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 13913916777	cfzhang@aikonchem.com	China	19902	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1246	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58
Aladdin Scientific		tp@aladdinsci.com	United States	50089	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49709	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55
EMMX Biotechnology LLC	60
Amadis Chemical Company Limited	58
Beijing Biocreative Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58

View Lastest Price from AF-DX 384 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	AFDX384 118290-27-0	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

AFDX384
118290-27-0
$1520.00-2500.00
TargetMol Chemicals Inc.

118290-27-0(AF-DX 384)Related Search:

(1-Ethyl-2-piperidinyl)-N-methylmethanamine Ethyl[(1-ethylpiperidin-2-yl)methyl]amine N-[(1-Methyl-2-piperidinyl)methyl]-1-propanamine Ethyl[(1-methylpiperidin-2-yl)methyl]amine Dimethyl-piperidin-2-ylmethyl-amine

2-(2-Diethylaminoethyl)piperidine N-[(1-Ethyl-2-piperidinyl)methyl]-1-propanamine Af-dx 384, [2,3-dipropylamino-3H]- 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one AF-DX 384

N-(piperidin-2-ylmethyl)-N,N-dipropylamine 2-(2-methylpiperidin-1-yl)ethanamine 2-amino-N-(3-pyridinyl)benzamide 1-ethylpiperidine-2-methylamine CHEMBRDG-BB 4015189

3-Amino-2-phenylamino-pyridine

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AF-DX 384 N-[2-[2-[(DIPROPYLAMINO)METHYL]-1-PIPERIDINYL]ETHYL]-5,6-DIHYDRO-6-OXO-11H-PYRIDO[2,3-B][1,4]BENZODIAZEPINE-11-CARBOXAMIDE N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxami N-(2-(2-((DIPROPYLAMINO)METHYL)PIPERIDIN-1-YL)ETHYL)-6-OXO-5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPINE-11(6H)-CARBOXAMIDE AF-DX 384 methanesulfonate 11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-, methanesulfonate (1:1) AF-DX 384, M2/M4 antagonist 118290-27-0 C27H38N6O2 Acetylcholine receptor