N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide
- CAS No.
- 78441-82-4
- Chemical Name:
- N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide
- Synonyms
- BMY-25271;BMY25271,BMY 25271;N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide;1,2,5-Thiadiazole-3,4-diamine, N3-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-, 1-oxide;4-[2-[[5-[(Dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethylimino]-1-oxido-1,2,5-thiadiazol-1-ium-3-amine
- CBNumber:
- CB52216356
- Molecular Formula:
- C12H19N5O2S2
- Molecular Weight:
- 329.44
- MDL Number:
- MFCD30533313
- MOL File:
- 78441-82-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Properties
| storage temp. | Store at -20°C |
|---|---|
| solubility | Soluble in DMSO |
| FDA UNII | SSC84DMZ28 |
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | DDA44182 | 4-[2-[[5-[(Dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethylimino]-1-oxido-1,2,5-thiadiazol-1-ium-3-amine | 78441-82-4 | 1mg | $2363.01 | 2026-06-04 | Buy |
| CSNpharm | CSN22167 | BMY-25271 | 78441-82-4 | 1mg | $958 | 2021-12-16 | Buy |
| CSNpharm | CSN22167 | BMY-25271 | 78441-82-4 | 5mg | $1533 | 2021-12-16 | Buy |
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Chemical Properties,Uses,Production
Uses
BMY-25271 is a histamine H2 receptor antagonist.
Biological Activity
BMY-25271 is a histamine H2 receptor antagonist.
in vivo
BMY-25271 is a histamine H2 receptor antagonist. The dose response curves are parallel and oral ED 50 values derived from probit analysis are 0.093, 0.97 and 6.9 mg/kg for BMY- 25271, ranitidine and cimetidine, respectively. Therefore it is about 10 and 74 times more potent than ranitidine and cimetidine, respectively.
target
Histamine H2 receptor
IC 50
H2 Receptor
References
[1] Cavanagh RL, et al. Prevention of aspirin-induced gastric mucosal injury by histamine H2 receptor antagonists: a crossover endoscopic and intragastric pH study in the dog. J Pharmacol Exp Ther. 1987 Dec;243(3):1179-84. PMID:2891837
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10233 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Supplier | Advantage |
|---|---|
| Fan De(Beijing) Biotechnology Co., Ltd. | 58 |
| BOC Sciences | 58 |
| TargetMol Chemicals Inc. | 58 |
| cjbscvictory | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |






