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γ-Linolenic Acid Ethyl Ester

CAS No.
31450-14-3
Chemical Name:
γ-Linolenic Acid Ethyl Ester
Synonyms
Ethyl γ-linolenate;Ethyl linolenate gamma;Ethyl gamma-linolenate;Ethyl gamma-linolenic acid;GAMMA-LINOLENIC ACID ETHYL ESTER;Ethyl Gamma-Linolenic Acid(C18:3);Gamma Linolenic Acid Ethyl Ester (90%);Ethyl 6(Z),9(Z),12(Z)-octadecatrienoate;6,9,12-OCTADECATRIENOIC ACID ETHYL ESTER;Gamma Linolenic acid ethyl ester (GLA-EE)
CBNumber:
CB5229451
Molecular Formula:
C20H34O2
Molecular Weight:
306.48
MDL Number:
MFCD00056309
MOL File:
31450-14-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:17:00

γ-Linolenic Acid Ethyl Ester Properties

Boiling point 390.6±31.0 °C(Predicted)
Density 0.893±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form liquid
color Colourless
Stability Light Sensitive
InChI InChI=1S/C20H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-4-2/h8-9,11-12,14-15H,3-7,10,13,16-19H2,1-2H3/b9-8-,12-11-,15-14-
InChIKey MJLYTDAIYLGSRZ-ORZIMQNZSA-N
SMILES C(OCC)(=O)CCCC/C=C\C/C=C\C/C=C\CCCCC
LogP 7.562 (est)
FDA UNII Z2942E0NCT

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
WGK Germany  3
NFPA 704
3
2 0

γ-Linolenic Acid Ethyl Ester price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9000738 γ-Linolenic Acid ethyl ester ≥98% 31450-14-3 50mg $38 2026-04-30 Buy
Cayman Chemical 9000738 γ-Linolenic Acid ethyl ester ≥98% 31450-14-3 100mg $71 2026-04-30 Buy
Cayman Chemical 9000738 γ-Linolenic Acid ethyl ester ≥98% 31450-14-3 250mg $165 2026-04-30 Buy
Cayman Chemical 9000738 γ-Linolenic Acid ethyl ester ≥98% 31450-14-3 1g $435 2026-04-30 Buy
TRC TRC-L467680-250MG gamma-Linolenic Acid Ethyl Ester 31450-14-3 250mg $180 2026-06-03 Buy
Product number Packaging Price Buy
9000738 50mg $38 Buy
9000738 100mg $71 Buy
9000738 250mg $165 Buy
9000738 1g $435 Buy
TRC-L467680-250MG 250mg $180 Buy

γ-Linolenic Acid Ethyl Ester Chemical Properties,Uses,Production

Description

γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B4 (LTB4) receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki value of 1 μM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction. GLA ethyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets.

Uses

γ-Linolenic Acid Ethyl Ester is used in biological studies for neoplasm inhibition of cultured carcinoma cells of human breast. This analog is also used in the evaluation of hypocholesterolemic activity in rats by comparing it with γ-Linolenic Acid (L467660).

Definition

ChEBI: Gamma-Linolenic acid ethyl ester is a long-chain fatty acid ethyl ester.

Purification Methods

To highly purify γ-linolenic acid (GLA) from microbial lipids, various types of zeolites were investigated in a fixed-bed column system, where a two-step desoprtion operation mode was found to be superior in selective separation of GLA. By this system, GLA ethyl ester of 98 mol% purity was obtained from a mixture of various polysaturated and unsaturated fatty acid esters using cesium Y and methyl-, dimethyl- and ethylammonium Y zeolites[1].

References

[1] MAKOTO ARAI Hisashi M Hideki Fukuda. Selective separation of γ-linolenic acid ethyl ester using y-zeolite[J]. Journal of Fermentation Technology, 1987. DOI:10.1016/0385-6380(87)90118-X.

γ-Linolenic Acid Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 77)Suppliers
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
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Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
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Shanghai Biological Technology Development Co., Ltd. 021-69955236-807 13918189704 chinaruji@chinaruji.com China 5093 55

View Lastest Price from γ-Linolenic Acid Ethyl Ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GAMMA-LINOLENIC ACID ETHYL ESTER pictures 2019-07-06 GAMMA-LINOLENIC ACID ETHYL ESTER
31450-14-3
$7.00 1KG 99% 100kg Career Henan Chemical Co
6,9,12-OCTADECATRIENOIC ACID ETHYL ESTER GAMMA-LINOLENIC ACID ETHYL ESTER DELTA 6 CIS 9 CIS 12 CIS OCTADECATRIENOIC ACID ETHYL ESTER 6,9,12-Octadecatrienoic acid, ethyl ester, (6Z,9Z,12Z)- γ-Linolenic acid ethyl ester, 6,9,12-Octadecatrienoic acid ethyl ester Ethyl linolenate gamma (6Z,9Z,12Z)-6,9,12-Octadecatrienoic acid ethyl ester Ethyl gamma-linolenate Ethyl gamma-linolenic acid Ethyl (6Z,9Z,12Z)-octadeca-6,9,12-trienoate Gamma Linolenic Acid Ethyl Ester (90%) Gamma Linolenic acid ethyl ester (GLA-EE) Ethyl linolenate gamma@10 mg/mL in Hexane cis-6,cis-9,cis-12 Octadecadienoic acid ethyl ester Ethyl Gamma-Linolenic Acid(C18:3) (6Z,9Z,12Z)-ethyl octadeca-6,9,12-trienoate Ethyl 6(Z),9(Z),12(Z)-octadecatrienoate Ethyl (6Z,9Z,12Z)-6,9,12- octadecatrienoic acid All Cis 6-9-12 Octadecatrienoic Ethyl Ester γ-Linolenic Acid Ethyl Ester, CAS 31450-14-3 Ethyl γ-linolenate (6Z,9Z,12Z)-Octadecatrienoic Acid Ethyl Ester 31450-14-3 Biochemicals and Reagents BioChemical Fatty Acids Ethyl Ester Esters Lipids Unsaturated fatty acids and derivatives