Methyl 6-methylbenzofuran-2-carboxylate
- CAS No.
- 82788-37-2
- Chemical Name:
- Methyl 6-methylbenzofuran-2-carboxylate
- Synonyms
- Methyl 6-methylbenzofuran-2-carboxylate;methyl 6-methyl-1-benzofuran-2-carboxylate;6-Methyl-2-benzofurancarboxylic acid methyl ester;2-Benzofurancarboxylic acid, 6-methyl-, methyl ester
- CBNumber:
- CB52466809
- Molecular Formula:
- C11H10O3
- Molecular Weight:
- 190.2
- MDL Number:
- MFCD11975072
- MOL File:
- 82788-37-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
Methyl 6-methylbenzofuran-2-carboxylate price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 303142 | Methyl 6-methylbenzofuran-2-carboxylate | 82788-37-2 | 1.00g | $71 | 2026-05-19 | Buy |
| Matrix Scientific | 303142 | Methyl 6-methylbenzofuran-2-carboxylate | 82788-37-2 | 5.00g | $193 | 2026-05-19 | Buy |
| Matrix Scientific | 303142 | Methyl 6-methylbenzofuran-2-carboxylate | 82788-37-2 | 10.00g | $382 | 2026-05-19 | Buy |
| aablocks | AA00G9FZ | Methyl 6-methylbenzofuran-2-carboxylate 98% | 82788-37-2 | 250mg | $24 | 2026-05-28 | Buy |
| aablocks | AA00G9FZ | Methyl 6-methylbenzofuran-2-carboxylate 98% | 82788-37-2 | 1g | $48 | 2026-05-28 | Buy |
Methyl 6-methylbenzofuran-2-carboxylate Chemical Properties, Uses, Production
Synthesis
67-56-1
50779-65-2
82788-37-2
At room temperature, 6-methylbenzofuran-2-carboxylic acid (11 g, 62.4 mmol) was dissolved in a solvent mixture of toluene (468 mL) and methanol (156 mL). 2N trimethylsilyl diazomethane (TMS-CHN2, 46.8 mL, 94 mmol) was slowly added dropwise to the above solution. The reaction mixture was stirred continuously for 6 hours at room temperature. Upon completion of the reaction, the reaction was quenched by dropwise addition of acetic acid at 0 °C until the yellow color of the solution disappeared and no gas escaped. Subsequently, the reaction mixture was concentrated under reduced pressure to remove the solvent and the residue was purified by rapid chromatography on silica gel with a gradient of 100% heptane to 10% ethyl acetate/90% heptane as eluent to yield methyl 6-methylbenzofuran-2-carboxylate (7.96 g). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 2.46 (s, 3H), 3.88 (s, 3H), 7.20 (dd, J=8.3,1.0 Hz, 1H), 7.53 (s, 1H), 7.67 (d, J=8.1 Hz, 1H), 7.71 (d, J=1.0 Hz, 1H).
References
[1] Bollettino Scientifico della Facolta di Chimica Industriale di Bologna, 1952, vol. 10, p. 168
[2] Patent: WO2015/161052, 2015, A1. Location in patent: Page/Page column 48
Methyl 6-methylbenzofuran-2-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 6-methylbenzofuran-2-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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| Taizhou Nanfeng Pharmaceutical Research Institute | nanfengpharma@126.co 18616377689 | nanfengpharma@126.com | China | 20008 | 58 |
| Henan Weitesi Chemical Technology Co. LTD | 0371-55135753 18003832934 | 3842570495@qq.com | China | 9992 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
