Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3,3'-Diamino-4,4'-dihydroxydiphenylmethane

3,3'-Diamino-4,4'-dihydroxydiphenylmethane

3,3'-Diamino-4,4'-dihydroxydiphenylmethane Structure
3,3'-Diamino-4,4'-dihydroxydiphenylmethane structure
CAS No.
16523-28-7
Chemical Name:
3,3'-Diamino-4,4'-dihydroxydiphenylmethane
Synonyms
4,4'-Methylenebis(2-aminophenol);FMP-API-1;FMP-API-1 >=98% (HPLC);4,4′-Methylenebis(2-aminophenol);Phenol, 4,4'-methylenebis[2-amino-;Bis(3-amino-4-hydroxyphenyl)methane;2,2'-diaMino-4,4'-Methanediyl-di-phenol;3,3'-Diamino-4,4'-dihydroxydiphenylmethane;2-amino-4-[(3-amino-4-hydroxy-phenyl)methyl]phenol
CBNumber:
CB52493630
Molecular Formula:
C13H14N2O2
Molecular Weight:
230.26
MDL Number:
MFCD00443347
MOL File:
16523-28-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:07:43
Request For Quotation

3,3'-Diamino-4,4'-dihydroxydiphenylmethane Properties

Melting point 220-222 °C (decomp)
Boiling point 372.26°C (rough estimate)
Density 1.1372 (rough estimate)
refractive index 1.6450 (estimate)
storage temp. -20°C
solubility DMSO: >10mg/mL
pka 10.24±0.10(Predicted)
form powder
color white to beige
InChI InChI=1S/C13H14N2O2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7,16-17H,5,14-15H2
InChIKey KCFVSHSJPIVGCG-UHFFFAOYSA-N
SMILES C(C1=CC=C(O)C(N)=C1)C1=CC=C(O)C(N)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36-43-52
Safety Statements  26-36/37
WGK Germany  3

3,3'-Diamino-4,4'-dihydroxydiphenylmethane price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0333919 FMP-API-1 95+% 16523-28-7 5g $2004 2026-06-04 Buy
Matrix Scientific 027747 2-Amino-4-(3-amino-4-hydroxybenzyl)phenol 16523-28-7 500.00mg $252 2026-05-18 Buy
Matrix Scientific 027747 2-Amino-4-(3-amino-4-hydroxybenzyl)phenol 16523-28-7 1.00g $388 2026-05-18 Buy
aablocks AA001VX9 4,4'-Methylenebis(2-aminophenol) 16523-28-7 500mg $365 2026-05-28 Buy
aablocks AA001VX9 4,4'-Methylenebis(2-aminophenol) 16523-28-7 1g $535 2026-05-28 Buy
Product number Packaging Price Buy
CS-0333919 5g $2004 Buy
027747 500.00mg $252 Buy
027747 1.00g $388 Buy
AA001VX9 500mg $365 Buy
AA001VX9 1g $535 Buy

3,3'-Diamino-4,4'-dihydroxydiphenylmethane Chemical Properties, Uses, Production

Uses

FMP-API-1 is an A-kinase anchoring protein (AKAP)-PKA interaction inhibitor. FMP-API-1 binds to the allosteric site of PKA R subunits and increases the activity of PKA and AQP2 in PKA-knockout cell lines of renal cortical collecting ducts (mpkCCD cells). FMP-API-1 has the potential for the study of nephrogenic diabetes insipidus (NDI)[1][2].

References

[1] Ando F. Activation of AQP2 water channels by protein kinase A: therapeutic strategies for congenital nephrogenic diabetes insipidus. Clin Exp Nephrol. 2021 Oct;25(10):1051-1056. DOI:10.1007/s10157-021-02108-6
[2] Fumiaki Ando, et al. AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus. Nat Commun. 2018 Apr 12;9(1):1411. DOI:10.1038/s41467-018-03771-2

3,3'-Diamino-4,4'-dihydroxydiphenylmethane Preparation Products And Raw materials

Raw materials

Preparation Products

3,3'-Diamino-4,4'-dihydroxydiphenylmethane Suppliers

Global Suppliers ( 30)
Supplier Tel Email Country ProdList Advantage
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Wellman Pharmaceutical Group Limited 15807197853 18971451745 15807197853@163.com China 3977 58
Changzhou Pesan Chemical Co.,Ltd. +86-021-61559630 +86-13761092941 zhangk@pesanchem.com China 1993 58
Hunan chemfish Scientific co.,ltd 85567275 18932438858 sales06@chemfish.com China 5003 58
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 info@rovathin.com.cn China 9958 58
CD Chemical Group Limited +86-13651442114 info@codchem.com China 17253 58
Shanxi Xuanran Import and Export Trade Co., Ltd. +8617735180244 mike_yan@xuanranglobal.com CHINA 4011 58
Nanjing jinheyou Trading Co., Ltd. 15705188088 admin@jheyou.com CHINA 1267 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Henan Weitixi Chemical Technology Co., Ltd 0371-53370800 18037197114 3807961510@qq.com China 9977 58
Supplier Advantage
Amadis Chemical Company Limited 58
Wellman Pharmaceutical Group Limited 58
Changzhou Pesan Chemical Co.,Ltd. 58
Hunan chemfish Scientific co.,ltd 58
Suzhou Rovathin Foreign Trade Co.,Ltd 58
CD Chemical Group Limited 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 58
Nanjing jinheyou Trading Co., Ltd. 58
Energy Chemical 58
Henan Weitixi Chemical Technology Co., Ltd 58

View Latest Price from 3,3'-Diamino-4,4'-dihydroxydiphenylmethane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,3'-Diamino-4,4'-dihydroxydiphenylmethane pictures 2026-09-07 3,3'-Diamino-4,4'-dihydroxydiphenylmethane
16523-28-7
 1g 99%MIN 2000G HANGZHOU HAILAN CHEMICAL CO.,LTD.
3,3'-Diamino-4,4'-dihydroxydiphenylmethane pictures 2019-11-08 3,3'-Diamino-4,4'-dihydroxydiphenylmethane
16523-28-7
 1g 98%min 20kg/month Nanjing jinheyou Trading Co., Ltd.

16523-28-7 (3,3'-Diamino-4,4'-dihydroxydiphenylmethane) Related Search:

2,2-Bis(3-amino-4-hydroxyphenyl)propane Bis(5-Amino-2-hydroxyphenyl)methan dihydrochloride 2-amino-4-benzylphenol 3,3'-Dihydroxy-4,4'-diaminodiphenylmethane Bis(3-amino-4-hydroxyphenyl)methanone
Phenol, 4-[(4-aminophenyl)methyl]-

1of2

3,3'-Diamino-4,4'-dihydroxydiphenylmethane 2,2'-diaMino-4,4'-Methanediyl-di-phenol 4,4′-Methylenebis(2-aminophenol) Bis(3-amino-4-hydroxyphenyl)methane FMP-API-1 2-amino-4-[(3-amino-4-hydroxy-phenyl)methyl]phenol Phenol, 4,4'-methylenebis[2-amino- FMP-API-1 >=98% (HPLC) 4,4'-Methylenebis(2-aminophenol) 16523-28-7