10-Methoxycarbamazepine
- CAS No.
- 28721-09-7
- Chemical Name:
- 10-Methoxycarbamazepine
- Synonyms
- 10-Methoxy-5H-dibenzo[b,f]azepine-5-carboxaMide;Oxcarbazepine-2;P2X4 antagonist-5;OXCARBAZEPINE EP IMP B;Oxcarbazepine Impurity 6;Oxcarbazepine IMpurity C;10-METHOXY CARBAMAZEPINE;Oxcarbazepine impurities3;Oxcarbazepine impurities103;10-methoxy-5h-dibenz(b,f)azepine-5-carboxamide
- CBNumber:
- CB5250987
- Molecular Formula:
- C16H14N2O2
- Molecular Weight:
- 266.29
- MDL Number:
- MFCD08460125
- MOL File:
- 28721-09-7.mol
- MSDS File:
- SDS
| Melting point | 186-188°C |
|---|---|
| Boiling point | 468.0±55.0 °C(Predicted) |
| Density | 1.31 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 13.86±0.40(Predicted) |
| form | Solid |
| color | Off-White |
| Major Application | pharmaceutical small molecule |
| CAS DataBase Reference | 28721-09-7(CAS DataBase Reference) |
| FDA UNII | Q13NU3QR2X |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
10-Methoxycarbamazepine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FM25175 | 10-Methoxy carbamazepine | 28721-09-7 | 250mg | $227.5 | 2026-06-04 | Buy |
| Biosynth | FM25175 | 10-Methoxy carbamazepine | 28721-09-7 | 500mg | $305 | 2026-06-04 | Buy |
| Biosynth | FM25175 | 10-Methoxy carbamazepine | 28721-09-7 | 1000mg | $410 | 2026-06-04 | Buy |
| Biosynth | FM25175 | 10-Methoxy carbamazepine | 28721-09-7 | 2000mg | $700 | 2026-06-04 | Buy |
| Biosynth | FM25175 | 10-Methoxy carbamazepine | 28721-09-7 | 5000mg | $1300 | 2026-06-04 | Buy |
10-Methoxycarbamazepine Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Intermediate in the preparation of dibenzazepine derivatives.
Synthesis
4698-11-7
32315-10-9
28721-09-7
1. 32.67 g (0.11 mol) of triphosgene dissolved in 300 mL of toluene was slowly added dropwise over a period of 6 hours to a mixture of 66.9 g (0.3 mol) of 10-methoxy-5H-dibenzo[b,f]azepine and 34.92 g (0.34 mol) of triethylamine in 800 mL of toluene at a temperature of 10-15 °C. 2. After completion of the reaction ( complete disappearance of 10-methoxy-5H-dibenz[b,f]azepine was confirmed by TLC monitoring), 200 mL of 30% ammonia was slowly added with vigorous stirring for several hours at room temperature.3. After the reaction mixture was layered, the organic phase was separated, the toluene phase was washed with water, and the reaction mixture was subsequently evaporated to dryness under reduced pressure.4. 69.0 g (85% of the theoretical yield) was obtained of a purity greater than 95% of 10-methoxy-5H-dibenz[b,f]azepine. Methoxy-5H-dibenz[b,f]azepine-5-carboxamide.
References
[1] Patent: EP1600443, 2005, A1. Location in patent: Page/Page column 8
10-Methoxycarbamazepine Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6746 | 52 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 5000 | 50 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Hubei XinyuanShun Chemical Co., Ltd. | 13971561712, 13995564702, 027-50664929 | hbeixys2001@163.com | China | 3110 | 55 |
View Lastest Price from 10-Methoxycarbamazepine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 10-Methoxycarbamazepine
28721-09-7
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- 10-Methoxycarbamazepine
28721-09-7
- $9.80
- ≥98%
- Career Henan Chemical Co
