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10-Methoxycarbamazepine

CAS No.
28721-09-7
Chemical Name:
10-Methoxycarbamazepine
Synonyms
10-Methoxy-5H-dibenzo[b,f]azepine-5-carboxaMide;Oxcarbazepine-2;P2X4 antagonist-5;OXCARBAZEPINE EP IMP B;Oxcarbazepine Impurity 6;Oxcarbazepine IMpurity C;10-METHOXY CARBAMAZEPINE;Oxcarbazepine impurities3;Oxcarbazepine impurities103;10-methoxy-5h-dibenz(b,f)azepine-5-carboxamide
CBNumber:
CB5250987
Molecular Formula:
C16H14N2O2
Molecular Weight:
266.29
MDL Number:
MFCD08460125
MOL File:
28721-09-7.mol
Last updated:2026-01-13 11:23:02
Product description Number Pack Size Price
10-MethoxyCarbamazepine M261260 1g $75
10-Methoxycarbamazepine J40047 25mg $48
10-Methoxycarbamazepine E616 1g $58
10-METHOXY CARBAMAZEPINE 95.00% CHM0017561 25MG $704.55
10-METHOXY CARBAMAZEPINE 95.00% CHM0017561 250MG $1593.9
More product size

10-Methoxycarbamazepine Properties

Melting point 186-188°C
Boiling point 468.0±55.0 °C(Predicted)
Density 1.31
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 13.86±0.40(Predicted)
form Solid
color Off-White
Major Application pharmaceutical small molecule
CAS DataBase Reference 28721-09-7(CAS DataBase Reference)
FDA UNII Q13NU3QR2X
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22

10-Methoxycarbamazepine price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M261260 10-MethoxyCarbamazepine 28721-09-7 1g $75 2021-12-16 Buy
AK Scientific J40047 10-Methoxycarbamazepine 28721-09-7 25mg $48 2021-12-16 Buy
AK Scientific E616 10-Methoxycarbamazepine 28721-09-7 1g $58 2021-12-16 Buy
American Custom Chemicals Corporation CHM0017561 10-METHOXY CARBAMAZEPINE 95.00% 28721-09-7 25MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation CHM0017561 10-METHOXY CARBAMAZEPINE 95.00% 28721-09-7 250MG $1593.9 2021-12-16 Buy
Product number Packaging Price Buy
M261260 1g $75 Buy
J40047 25mg $48 Buy
E616 1g $58 Buy
CHM0017561 25MG $704.55 Buy
CHM0017561 250MG $1593.9 Buy

10-Methoxycarbamazepine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of dibenzazepine derivatives.

Synthesis

10-Methoxyiminostilbene

4698-11-7

Triphosgene

32315-10-9

10-Methoxycarbamazepine

28721-09-7

1. 32.67 g (0.11 mol) of triphosgene dissolved in 300 mL of toluene was slowly added dropwise over a period of 6 hours to a mixture of 66.9 g (0.3 mol) of 10-methoxy-5H-dibenzo[b,f]azepine and 34.92 g (0.34 mol) of triethylamine in 800 mL of toluene at a temperature of 10-15 °C. 2. After completion of the reaction ( complete disappearance of 10-methoxy-5H-dibenz[b,f]azepine was confirmed by TLC monitoring), 200 mL of 30% ammonia was slowly added with vigorous stirring for several hours at room temperature.3. After the reaction mixture was layered, the organic phase was separated, the toluene phase was washed with water, and the reaction mixture was subsequently evaporated to dryness under reduced pressure.4. 69.0 g (85% of the theoretical yield) was obtained of a purity greater than 95% of 10-methoxy-5H-dibenz[b,f]azepine. Methoxy-5H-dibenz[b,f]azepine-5-carboxamide.

References

[1] Patent: EP1600443, 2005, A1. Location in patent: Page/Page column 8

4698-11-7
32315-10-9
28721-09-7
Synthesis of 10-Methoxycarbamazepine from 10-Methoxyiminostilbene and Triphosgene
Global( 146)Suppliers
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Nanjing ChemLin Chemical Industry Co., Ltd.
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CR Corporation Limited
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sgtlifesciences pvt ltd
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View Lastest Price from 10-Methoxycarbamazepine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
10-Methoxycarbamazepine pictures 2020-01-10 10-Methoxycarbamazepine
28721-09-7
US $9.80 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
10-methoxy-5h-dibenz(b,f)azepine-5-carboxamide 10-METHOXY CARBAMAZEPINE 10-METHOXY-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE 98.5% 10-Methoxy-5H-dibenzo[b,f]azepine-5-carboxaMide Oxcarbazepine IMpurity C Oxcarbazepine Impurity 6 Oxcarbazepine Impurity 2(Oxcarbazepine EP Impurity B) Oxcarbazepine-2 5-methoxy-11-benzo[b][1]benzazepinecarboxamide 5H-Dibenz[b,f]azepine-5-carboxamide, 10-methoxy- Oxcarbazepine EP Impurity B (10-Methoxycarbamazepine) Oxcarbazepine impurities103 Oxcarbazepine impurities3 10-methoxy carbamazepineQ: What is 10-methoxy carbamazepine Q: What is the CAS Number of 10-methoxy carbamazepine Q: What is the storage condition of 10-methoxy carbamazepine Q: What are the applications of 10-methoxy carbamazepine 10-methoxy-5h-dibenzo[b,f]azepine-5-carboxamide(10-methoxycarbamazepine), OXCARBAZEPINE EP IMP B 10-Methoxycarbamazepine (10-Methoxy-5H-dibenz[b,f]azepine-5-carboxamide) P2X4 antagonist-5 10-Methoxy-5H-dibenzo[b,f]azepine-5-carboxamide - [M94789] 28721-09-7 28271-09-7 Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals