Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate
- CAS No.
- 1215205-50-7
- Chemical Name:
- Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate
- Synonyms
- EOS-60373;Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate;ethyl1-(4-bromophenyl)cyclopropane-1-carboxylate;1-(4-Bromo-phenyl)-cyclopropanecarboxylic acid ethyl ester;Cyclopropanecarboxylic acid, 1-(4-bromophenyl)-, ethyl ester
- CBNumber:
- CB52513554
- Molecular Formula:
- C12H13BrO2
- Molecular Weight:
- 269.13
- MDL Number:
- MFCD15143548
- MOL File:
- 1215205-50-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|---|---|
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235 |
Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS43474 | Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate 95% | 1215205-50-7 | 1g | $36 | 2026-06-04 | Buy |
| Activate Scientific | AS43474 | Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate 95% | 1215205-50-7 | 5g | $156 | 2026-06-04 | Buy |
| Matrix Scientific | 153525 | Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate | 1215205-50-7 | 10.00g | $1480 | 2026-05-18 | Buy |
| Matrix Scientific | 153525 | Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate | 1215205-50-7 | 25.00g | $2590 | 2026-05-18 | Buy |
| Synthonix | E55844 | Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate 95% | 1215205-50-7 | 250mg | $31 | 2026-05-06 | Buy |
Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate Chemical Properties, Uses, Production
Synthesis
14062-25-0
106-93-4
1215205-50-7
Example 14A Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate was synthesized as follows: first, 1.45 g (36.2 mmol) of sodium hydroxide (60% mineral oil dispersion) was suspended in 100 mL of anhydrous DMF. Subsequently, a mixture of 4.0 g (16.5 mmol) of ethyl p-bromophenylacetate with 6.5 g (34.6 mmol) of 1,2-dibromoethane was dissolved in 50 mL of anhydrous THF and this solution was added slowly and dropwise to the sodium hydride suspension. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate and washed sequentially with water and saturated sodium chloride solution. The organic phase was separated, dried with anhydrous magnesium sulfate, filtered and the filtrate concentrated. The residue was purified by preparative HPLC [column: Reprosil C18, 10 μm, 250 mm × 40 mm; mobile phase: 30% methanol/70% water to 100% methanol gradient elution, run time 25 min]. After HPLC analysis, the fractions containing the target product were combined and concentrated to give 1.15 g (26% yield) of the target product as a liquid. The product was characterized by GC-MS [Method 5] and 1H-NMR (400 MHz, DMSO-d6): GC-MS retention time Rt = 5.45 min; MS (ESIpos): m/z = 268/270 [M+]; 1H-NMR δ (ppm): 1.09 (t, 3H), 1.16-1.20 (m, 2H), 1.46-1.50 (m, 2H) 1.46-1.50 (m, 2H), 4.02 (q, 2H), 7.26-7.31 (m, 2H), 7.47-7.51 (m, 2H).
References
[1] Patent: US2016/318866, 2016, A1. Location in patent: Paragraph 0642; 0643; 06444; 0645
Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9959 | 58 |
| Suzhou Chenke Biotech Co., Ltd. | 18662408853 | 2120408911@qq.com | China | 980 | 55 |
| Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd | 18210788515; 18210788515 | zhuzixin999@163.c0m | China | 4998 | 55 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 | sales@shiyabiopharm.com | China | 9814 | 58 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
