Eriocalyxin B
- CAS No.
- 84745-95-9
- Chemical Name:
- Eriocalyxin B
- Synonyms
- Eriocalyxin B;5-trimethoxyphenol;Eriocalyxin B, 10 mM in DMSO;Kaura-2,16-diene-1,15-dione, 7,20-epoxy-6,7-dihydroxy-, (6β,7α)-;(4aR,5S,6S,6aS,9R,11aS,11bS)-5,6-Dihydroxy-4,4-dimethyl-8-methylene-4,4a,5,6,9,10,11,11a-octahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalene-1,7(8H)-dione
- CBNumber:
- CB52519723
- Molecular Formula:
- C20H24O5
- Molecular Weight:
- 344.41
- MDL Number:
- MFCD20260372
- MOL File:
- 84745-95-9.mol
- MSDS File:
- SDS
| Boiling point | 551.1±50.0 °C(Predicted) |
|---|---|
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| pka | 11.05±0.60(Predicted) |
| form | Solid |
| color | White to off-white |
| InChIKey | RTIKCEKESDRWAE-HCLRZYKANA-N |
| SMILES | O[C@@]12OC[C@]3(C(C=CC(C)(C)[C@@]3([H])[C@@H]1O)=O)[C@]1([H])CC[C@@]3([H])C(=C)C(=O)[C@@]21C3 |&1:1,4,11,13,16,20,26,r| |
Eriocalyxin B Chemical Properties,Uses,Production
Uses
Eriocalyxin B is an ent-Kaurene diterpenoid isolated from Chinese herb Isodon eriocalyx. Eriocalyxin B has anti-cancer and anti-infammatory activities. Eriocalyxin B induces cell apoptosis[1].
References
[1] Rong-Fang Mu, et al. Eriocalyxin B Inhibits Adipogenesis in 3T3-L1 Adipocytes by Cell Cycle Arrest. Nat Prod Bioprospect. 2020 Jun;10(3):131-140. DOI:10.1007/s13659-020-00240-6
[2] Wang WG, et al. Laxiflorolides A and B, epimeric bishomoditerpene lactones from Isodon eriocalyx. J Nat Prod. 2012 Jun 22;75(6):1102-7.
[3] Zhou X, et al. Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer. Biochem Pharmacol. 2017 Oct 15;142:58-70.
[4] Lu Y, et al. Eriocalyxin B ameliorates experimental autoimmune encephalomyelitis by suppressing Th1 and Th17 cells. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2258-63.
[5] Leung CH, et al. Eriocalyxin B inhibits nuclear factor-kappaB activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner. Mol Pharmacol. 2006 Dec;70(6):1946-55.Leung CH, Grill SP, Lam W, Gao W, Sun HD, Cheng YC. Eriocalyxin B inhibits nuclear factor-kappaB activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner. Mol Pharmacol. 2006 Dec;70(6):1946-55.
Eriocalyxin B Preparation Products And Raw materials
Raw materials
Preparation Products
Eriocalyxin B Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32376 | 58 |
| Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | chem1022@hengdian-group.com | China | 1478 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 |
View Lastest Price from Eriocalyxin B manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-28 | Eriocalyxin B
84745-95-9
|
US $313.00-973.00 / mg | 99.84% | 10g | TargetMol Chemicals Inc. |
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- Eriocalyxin B
84745-95-9
- US $313.00-973.00 / mg
- 99.84%
- TargetMol Chemicals Inc.
