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1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester

1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester structure

CAS No.: 946427-77-6

Chemical Name:: 1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester

Synonyms: Methyl 6-bromo-1-methyl-1...;Methyl 6-bromo-1-methylindazole-3-carboxylate;Methyl 6-bromo-1-methyl-1H-indazole-3-carboxyl;Methyl 6-broMo-1-Methyl-1H-indazole-3-carboxylate;6-bromo-1-methyl-1H-indazole-3-carboxylic acid methyl ester;1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester

CBNumber:: CB52525137

Molecular Formula:: C10H9BrN2O2

Molecular Weight:: 269.09

MDL Number:: MFCD15071437

MOL File:: 946427-77-6.mol

Last updated:2025-07-24 18:13:53

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1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester Properties

Boiling point	366.7±22.0 °C(Predicted)
Density	1.61±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	-1.74±0.50(Predicted)
Appearance	Off-white to light yellow Solid

1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0048947	Methyl6-bromo-1-methyl-1H-indazole-3-carboxylate	946427-77-6	100mg	$214	2021-12-16	Buy
ChemScene	CS-0048947	Methyl6-bromo-1-methyl-1H-indazole-3-carboxylate	946427-77-6	250mg	$357	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0419465	METHYL-6-BROMO-1-METHYL-1H-INDAZOLE-3-CARBOXYLATE 95.00%	946427-77-6	5MG	$455.03	2021-12-16	Buy
SynQuest Laboratories	4H58-9-0V	Methyl 6-bromo-1-methyl-1H-indazole-3-carboxylate 97.0%	946427-77-6	250mg	$600	2021-12-16	Buy
Matrix Scientific	068469	Methyl 6-bromo-1-methyl-1H-indazole-3-carboxylate >95%	946427-77-6	250mg	$700	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0048947	100mg	$214	Buy
CS-0048947	250mg	$357	Buy
HCH0419465	5MG	$455.03	Buy
4H58-9-0V	250mg	$600	Buy
068469	250mg	$700	Buy

1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester Chemical Properties,Uses,Production

Synthesis

METHYL 6-BROMO-1H-INDAZOLE-3-CARBOXYLATE

885278-42-2

74-88-4

1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester

946427-77-6

Intermediate Preparation 411B; Methyl 6-bromo-1-methyl-1H-indazole-3-carboxylate; To a suspension of methyl 6-bromo-1H-indazole-3-carboxylate (0.50 g, 1.96 mmol) and potassium carbonate (1.28 g, 9.29 mmol) in acetonitrile (15 mL) was added methiodine (1.31 g, 9.29 mmol). The reaction mixture was stirred at room temperature for 15 hours. After completion of the reaction, the solvent was removed under vacuum and the residue was diluted with water (15 mL) and extracted with ethyl acetate (3 x 10 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by fast column chromatography using 8:2 hexane/ethyl acetate as eluent to afford 0.35 g (70% yield) of methyl 6-bromo-1-methylindazole-3-carboxylate as an off-white solid.1H NMR (400 MHz, CDCl3) δ 4.03 (s, 3H), 4.14 (s, 3H), 7.42 (dd, J = 8.4, 1.2 Hz, 1H), 7.66 (s, 1H), 8.08 (d, J = 8.8 Hz, 1H).

References

[1] Patent: WO2009/12125, 2009, A1. Location in patent: Page/Page column 38
[2] Patent: WO2011/20615, 2011, A1. Location in patent: Page/Page column 85; 86
[3] Patent: WO2018/177781, 2018, A1. Location in patent: Page/Page column 82-83

1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester Preparation Products And Raw materials

Raw materials

METHYL 6-BROMO-1H-INDAZOLE-3-CARBOXYLATE Iodomethane Potassium carbonate Acetonitrile

Preparation Products

1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester Suppliers

Global( 38)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323658 +86-18168183658	sales1@artkmedchem.com	China	39002	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Shanghai Synthfine Chemical Co.,Ltd	15921303235	sales@synthfine.com	China	1072	58
Dtchem Laboratories,（Gan Su）Co.,Ltd.	18993966060	sales@techbiochem.com	China	770	61
Nantong Bosu Pharmaceutical Technology Co., Ltd.	0513-0513-51005092 13390947892	tashiyxy@163.com	China	844	58

Supplier	Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
Amadis Chemical Company Limited	58
Shanghai Synthfine Chemical Co.,Ltd	58
Dtchem Laboratories,（Gan Su）Co.,Ltd.	61
Nantong Bosu Pharmaceutical Technology Co., Ltd.	58

1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester Spectrum

Methyl 6-bromo-1-methyl-1...(946427-77-6)¹HNMR

946427-77-6(1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester)Related Search:

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Methyl 6-broMo-1-Methyl-1H-indazole-3-carboxylate Methyl 6-bromo-1-methyl-1H-indazole-3-carboxyl Methyl 6-bromo-1-methylindazole-3-carboxylate 1H-Indazole-3-carboxylic acid, 6-bromo-1-methyl-, methyl ester 6-bromo-1-methyl-1H-indazole-3-carboxylic acid methyl ester Methyl 6-bromo-1-methyl-1... 946427-77-6