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CytochroMe P450 14a-deMethylase inhibitor 1h

CytochroMe P450 14a-deMethylase inhibitor 1h structure

CAS No.: 1155361-06-0

Chemical Name:: CytochroMe P450 14a-deMethylase inhibitor 1h

Synonyms: CYP51-IN-8;CytochroMe P450 14a-deMethylase inhibitor 1h;1H-1,2,4-Triazole-1-ethanol, α-[[[(2-bromophenyl)methyl]-2-propen-1-ylamino]methyl]-α-(2,4-difluorophenyl)-

CBNumber:: CB52561474

Molecular Formula:: C21H21BrF2N4O

Molecular Weight:: 463.32

MDL Number:: MFCD18384997

MOL File:: 1155361-06-0.mol

Last updated:2025-04-18 09:51:08

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CytochroMe P450 14a-deMethylase inhibitor 1h Properties

Melting point	67.3-68.8 °C
Boiling point	590.771±60.00 °C(Press: 760.00 Torr)(predicted)
Density	1.379±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	11.925±0.29(predicted)

CytochroMe P450 14a-deMethylase inhibitor 1h price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FWB36106	Cytochrome P450 14a-demethylase inhibitor 1H	1155361-06-0	25mg	$837.5	2026-06-04	Buy
Biosynth	FWB36106	Cytochrome P450 14a-demethylase inhibitor 1H	1155361-06-0	50mg	$1340.5	2026-06-04	Buy
Biosynth	FWB36106	Cytochrome P450 14a-demethylase inhibitor 1H	1155361-06-0	100mg	$1866	2026-06-04	Buy
American Custom Chemicals Corporation	INB0000918	CYTOCHROME P450 14A-DEMETHYLASE INHIBITOR 1H 95.00%	1155361-06-0	10MG	$1006.58	2021-12-16	Buy
American Custom Chemicals Corporation	INB0000918	CYTOCHROME P450 14A-DEMETHYLASE INHIBITOR 1H 95.00%	1155361-06-0	50MG	$1734.23	2021-12-16	Buy

Product number	Packaging	Price	Buy
FWB36106	25mg	$837.5	Buy
FWB36106	50mg	$1340.5	Buy
FWB36106	100mg	$1866	Buy
INB0000918	10MG	$1006.58	Buy
INB0000918	50MG	$1734.23	Buy

CytochroMe P450 14a-deMethylase inhibitor 1h Chemical Properties,Uses,Production

Uses

CYP51-IN-2 (compound 1h), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80s of 15.6 and 62.5 ng/mL for Microsporum gypseum and Candida albicans, respectively[1].

References

[1] Chai X, et, al. Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase. Eur J Med Chem. 2009 May;44(5):1913-20. DOI:10.1016/j.ejmech.2008.11.007

CytochroMe P450 14a-deMethylase inhibitor 1h Preparation Products And Raw materials

Raw materials

Preparation Products

CytochroMe P450 14a-deMethylase inhibitor 1h Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai civi chemical technology co.,Ltd	86-21-34053660	sale@labgogo.com	China	9853	52
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
Shanghai civi chemical technology co.,Ltd	52
TargetMol	58

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CytochroMe P450 14a-deMethylase inhibitor 1h 1H-1,2,4-Triazole-1-ethanol, α-[[[(2-bromophenyl)methyl]-2-propen-1-ylamino]methyl]-α-(2,4-difluorophenyl)- CYP51-IN-8 1155361-06-0