1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE
- CAS No.
- 216076-11-8
- Chemical Name:
- 1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE
- Synonyms
- 1-(2-chlorophenyl)-2-(4-pyridyl)ethanone;1-(2-chlorophenyl)-2-(4-pyridinyl)Ethanone;1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE;Ethanone, 1-(2-chlorophenyl)-2-(4-pyridinyl)-
- CBNumber:
- CB5257148
- Molecular Formula:
- C13H10ClNO
- Molecular Weight:
- 231.68
- MDL Number:
- MFCD04114383
- MOL File:
- 216076-11-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 9402AH | 1-(2-Chloro-phenyl)-2-pyridin-4-yl-ethanone | 216076-11-8 | 250mg | $401 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0314147 | 1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE 98.00% | 216076-11-8 | 5MG | $496.46 | 2021-12-16 | Buy |
| Chemenu | CM171381 | 1-(2-Chloro-phenyl)-2-pyridin-4-yl-ethanone 95% | 216076-11-8 | 1g | $608 | 2021-12-16 | Buy |
| Alichem | 216076118 | 1-(2-Chlorophenyl)-2-(pyridin-4-yl)ethanone | 216076-11-8 | 1g | $630.5 | 2021-12-16 | Buy |
| Crysdot | CD11165230 | 1-(2-Chlorophenyl)-2-(pyridin-4-yl)ethanone 95+% | 216076-11-8 | 1g | $644 | 2021-12-16 | Buy |
1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE Chemical Properties,Uses,Production
Synthesis
108-89-4
289686-74-4
216076-11-8
1. A solution of 4-methylpyridine (1.07 g, 11.5 mmol) in THF (10.0 mL) was added slowly and dropwise to a solution of tetrahydrofuran (THF, 20.0 mL) containing lithium diisopropylammonium (6.5 mL, 1.6 M in cyclohexane, 10.4 mmol) at -78°C. 2. The dry ice bath was removed and the reaction mixture was stirred at 0 °C for 30 min and then re-cooled to -78 °C. 3. A solution of 2-chloro-N-methoxy-N-methylbenzamide (2.39 g, 12 mmol) in THF (10.0 mL) was added dropwise to the reaction mixture. 4. The reaction mixture was gradually warmed to room temperature and stirred overnight. 5. The resulting white solid was collected by filtration and dissolved in ethyl acetate. 6. The organic phase was washed sequentially with water and brine and then dried with anhydrous magnesium sulfate. 7. Vacuum concentration of the dried organic phase afforded the target product 1-(2-chlorophenyl)-2-(pyridin-4-yl)ethanone (1.09 g, 4.7 mmol, 47% yield) as a white solid.
References
[1] Patent: WO2009/91759, 2009, A1. Location in patent: Page/Page column 49
[2] Patent: WO2009/91760, 2009, A1. Location in patent: Page/Page column 41
1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1-(2-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Carlow Chemicals Co., Ltd. | 21-33526724 18930996265 | info@carlowchem.com | China | 1956 | 50 |
| Shanghai Brain Biotechnology Co., Ltd. | 13564638271 | shhjiang1977@163.com | China | 2981 | 55 |
| Yantai ShengKailun Chemical Technology Co., Ltd. | 13356901049 | 3119594100@qq.com | China | 7964 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28787 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 52693 | 58 |
| Nanjing Easichem Co. ltd. | 18061688856 | easichem@126.com | China | 477 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55055611 18137792234 | 3002694073@qq.com | China | 9993 | 58 |
