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2-aMino-6-chloronicotinonitrile

CAS No.
52471-07-5
Chemical Name:
2-aMino-6-chloronicotinonitrile
Synonyms
2-aMino-6-chloronicotinonitrile;2-AMino-6-chloro-3-cyanopyridine;2-Amino-6-chloropyridine-3-carbonitrile;2-amino-6-chloro-3-Pyridinecarbonitrile;3-Pyridinecarbonitrile, 2-amino-6-chloro-
CBNumber:
CB52606001
Molecular Formula:
C6H4ClN3
Molecular Weight:
153.57
MDL Number:
MFCD18261104
MOL File:
52471-07-5.mol
MSDS File:
SDS
Last updated:2026-05-28 03:33:48
Product description Number Pack Size Price
2-Amino-6-chloronicotinonitrile 95% AS43152 1g $135
2-Amino-6-chloronicotinonitrile 95% AS43152 5g $647
2-Amino-6-chloronicotinonitrile 95% AS43152 25g $1795
2-Amino-6-chloronicotinonitrile 119600 1.00g $79
2-Amino-6-chloronicotinonitrile 119600 5.00g $387

2-aMino-6-chloronicotinonitrile Properties

Boiling point 326.1±42.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka -0.87±0.10(Predicted)
form solid
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
HS Code  2933399990

2-aMino-6-chloronicotinonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS43152 2-Amino-6-chloronicotinonitrile 95% 52471-07-5 1g $135 2026-06-04 Buy
Activate Scientific AS43152 2-Amino-6-chloronicotinonitrile 95% 52471-07-5 5g $647 2026-06-04 Buy
Activate Scientific AS43152 2-Amino-6-chloronicotinonitrile 95% 52471-07-5 25g $1795 2026-06-04 Buy
Matrix Scientific 119600 2-Amino-6-chloronicotinonitrile 52471-07-5 1.00g $79 2026-05-18 Buy
Matrix Scientific 119600 2-Amino-6-chloronicotinonitrile 52471-07-5 5.00g $387 2026-05-18 Buy
Product number Packaging Price Buy
AS43152 1g $135 Buy
AS43152 5g $647 Buy
AS43152 25g $1795 Buy
119600 1.00g $79 Buy
119600 5.00g $387 Buy

2-aMino-6-chloronicotinonitrile Chemical Properties,Uses,Production

Synthesis

3-Pyridinecarboxaldehyde, 2-amino-6-chloro-, oxime, hydrochloride (1:1)

1062197-07-2

2-aMino-6-chloronicotinonitrile

52471-07-5

Example 15A Synthesis of 2-amino-6-chloropyridine-3-carbonitrile: First, 11.15 g (53.6 mmol) of 2-amino-6-chloropyridine-3-carboxaldehyde oxime hydrochloride (Example 14A) was suspended in dioxane, followed by the addition of 13 ml (161 mmol) of pyridine. After cooling the mixture to 0°C, 8.3 ml (58.95 mmol) of trifluoroacetic anhydride was slowly added dropwise. After the dropwise addition, the reaction mixture was gradually warmed to room temperature and stirred continuously at 60°C for 2 hours. After completion of the reaction, the mixture was dissolved in a mixed system of ethyl acetate and aqueous sodium bicarbonate. The organic phase was separated, washed with saturated aqueous sodium chloride solution, dried over anhydrous magnesium sulfate and subsequently concentrated on a rotary evaporator. The concentrated residue was suspended in a solvent mixture of dichloromethane and ether (3:1 v/v) and the solid product was collected by filtration and dried to give 5.56 g (66% yield) of the target compound as a solid. The product was analyzed by LCMS (Method 6): retention time Rt = 1.0 min, m/z = 154 (M + H)+. 1H-NMR (400 MHz, DMSO-d6) data: δ= 7.91 (d, 1H), 7.38 (s, 2H), 6.69 (d, 1H).

References

[1] Patent: US2009/258877, 2009, A1. Location in patent: Page/Page column 17-18
[2] Patent: US2010/113441, 2010, A1. Location in patent: Page/Page column 49
[3] Patent: US2011/190316, 2011, A1. Location in patent: Page/Page column 12

2-aMino-6-chloronicotinonitrile Preparation Products And Raw materials

2-aMino-6-chloronicotinonitrile Suppliers

Global( 58)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
Career Henan Chemica Co
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Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
+86-029-86185165 +86-18629664246 guoyuan@eastchinapharm.com China 1612 58
Aladdin Scientific
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Cochemical Co. Ltd.
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DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53799 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131885 58
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3979 55
Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd. 0515-89701588 13770166955 orgunion@orgunion.com China 620 55

2-aMino-6-chloronicotinonitrile Spectrum

2-aMino-6-chloronicotinonitrile 2-AMino-6-chloro-3-cyanopyridine 2-Amino-6-chloropyridine-3-carbonitrile 3-Pyridinecarbonitrile, 2-amino-6-chloro- 2-amino-6-chloro-3-Pyridinecarbonitrile 52471-07-5