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RPR-260243

RPR-260243 Structure
RPR-260243 structure
CAS No.
668463-35-2
Chemical Name:
RPR-260243
Synonyms
100866;CS-2094;RPR-260243;RPR 260243;RPR260243;(3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl];(3r,4r)-4-(3-(6-methoxyquinolin-4-yl)-3-oxopropyl)-1-(3-(2,3,5-trifluorophenyl)prop-2-yn-1-yl)piperidine-3-carboxylic acid;(3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid;3-Piperidinecarboxylic acid, 4-[3-(6-methoxy-4-quinolinyl)-3-oxopropyl]-1-[3-(2,3,5-trifluorophenyl)-2-propyn-1-yl]-, (3R,4R)-
CBNumber:
CB52645127
Molecular Formula:
C28H25F3N2O4
Molecular Weight:
510.5
MDL Number:
MFCD23136021
MOL File:
668463-35-2.mol
MSDS File:
SDS
Last updated:2026-05-28 04:11:07
Product description Number Pack Size Price
RPR-260243 TBB46335 25mg $1345.25
RPR-260243 TBB46335 50mg $1871
RPR-260243 99.91% CS-4322 5mg $444
RPR-260243 99.91% CS-4322 10mg $704
RPR-260243 99.91% CS-4322 25mg $1408
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RPR-260243 Properties

Boiling point 668.0±55.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at 2-8°C
solubility DMSO: 10 mg/mL (19.59 mM)
form Solid
pka 3.71±0.40(Predicted)
color Light yellow to light brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501

RPR-260243 price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth TBB46335 RPR-260243 668463-35-2 25mg $1345.25 2026-06-05 Buy
Biosynth TBB46335 RPR-260243 668463-35-2 50mg $1871 2026-06-05 Buy
ChemScene CS-4322 RPR-260243 99.91% 668463-35-2 5mg $444 2026-06-04 Buy
ChemScene CS-4322 RPR-260243 99.91% 668463-35-2 10mg $704 2026-06-04 Buy
ChemScene CS-4322 RPR-260243 99.91% 668463-35-2 25mg $1408 2026-06-04 Buy
Product number Packaging Price Buy
TBB46335 25mg $1345.25 Buy
TBB46335 50mg $1871 Buy
CS-4322 5mg $444 Buy
CS-4322 10mg $704 Buy
CS-4322 25mg $1408 Buy

RPR-260243 Chemical Properties,Uses,Production

Uses

RPR-260243, a potent activator of human ether-a-go-go-related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243-modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator-like effects on other voltage-dependent ion channels, including the closely related ERG3 K+ channel[1][2]. RPR-260243 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1] Wu W, et al. Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243. Mol Pharmacol. 2015;87(3):401-409. DOI:10.1124/mol.114.096693
[2] Kang J, et al. Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel. Mol Pharmacol. 2005;67(3):827-836. DOI:10.1124/mol.104.006577

RPR-260243 Preparation Products And Raw materials

Raw materials

Preparation Products

RPR-260243 Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39037 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131956 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
CEG Chemical Science&Technology Co., Ltd. Mobile:13665161512 China 1785 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9804 58
Musechem +1-800-259-7612 info@musechem.com United States 4660 60
Cckinase, Inc. +1 (732)236-3202 sales@cckinase.com United States 2738 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 63313187 15358055255 63313187@qq.com China 1984 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Amadis Chemical Company Limited 		58
MedChemexpress LLC 58
CEG Chemical Science&Technology Co., Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
Musechem 60
Cckinase, Inc. 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 58

View Lastest Price from RPR-260243 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RPR-260243 pictures 2026-05-11 RPR-260243
668463-35-2
 $1070.00-2090.00 10g TargetMol Chemicals Inc.
  • RPR-260243 pictures
  • RPR-260243
    668463-35-2
  • $1070.00-2090.00
  • TargetMol Chemicals Inc.
RPR-260243 (3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid (3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl] 100866 RPR 260243;RPR260243 CS-2094 3-Piperidinecarboxylic acid, 4-[3-(6-methoxy-4-quinolinyl)-3-oxopropyl]-1-[3-(2,3,5-trifluorophenyl)-2-propyn-1-yl]-, (3R,4R)- (3r,4r)-4-(3-(6-methoxyquinolin-4-yl)-3-oxopropyl)-1-(3-(2,3,5-trifluorophenyl)prop-2-yn-1-yl)piperidine-3-carboxylic acid 668463-35-2 C28H25F3N2O4