3-(4-fluorophenylaMino)-3-oxopropanoic acid
- CAS No.
- 95262-10-5
- Chemical Name:
- 3-(4-fluorophenylaMino)-3-oxopropanoic acid
- Synonyms
- Cabozantinib Impurity 68;3-(4-fluorophenylaMino)-3-oxopropanoic acid;Propanoic acid, 3-[(4-fluorophenyl)amino]-3-oxo-;3-((4-Fluorophenyl)amino)-3-oxopropanoic acid (Cabozantinib Impurity)
- CBNumber:
- CB52676471
- Molecular Formula:
- C9H8FNO3
- Molecular Weight:
- 197.16
- MDL Number:
- MFCD00201972
- MOL File:
- 95262-10-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
3-(4-fluorophenylaMino)-3-oxopropanoic acid price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS173135 | 3-(4-Fluorophenylamino)-3-oxopropanoic Acid 95% | 95262-10-5 | 1g | $32 | 2026-06-04 | Buy |
| Activate Scientific | AS173135 | 3-(4-Fluorophenylamino)-3-oxopropanoic Acid 95% | 95262-10-5 | 5g | $100 | 2026-06-04 | Buy |
| aablocks | AA00IITP | Propanoic acid, 3-[(4-fluorophenyl)amino]-3-oxo- 97% | 95262-10-5 | 250mg | $49 | 2026-05-29 | Buy |
| aablocks | AA00IITP | Propanoic acid, 3-[(4-fluorophenyl)amino]-3-oxo- 97% | 95262-10-5 | 1g | $63 | 2026-05-29 | Buy |
| aablocks | AA00IITP | Propanoic acid, 3-[(4-fluorophenyl)amino]-3-oxo- 97% | 95262-10-5 | 5g | $174 | 2026-05-29 | Buy |
3-(4-fluorophenylaMino)-3-oxopropanoic acid Chemical Properties, Uses, Production
Synthesis
Step 1: Synthesis of ethyl 3-(4-fluorophenylamino)-3-oxopropionate.
Organic solution of diethyl malonate was added to organic solution of 4-fluorophenylamine and heated to reflux until the reaction was complete. The reaction solution was cooled to room temperature, n-hexane was added to the reaction solution, filtered, the filter residue was washed with water, and the residue was recrystallized to give ethyl 3-(4-fluorophenylamino)-3-oxopropanoate.
Step 2: Synthesis of 3-(4-fluorophenylamino)-3-oxopropanoic acid.
An aqueous solution of base was added to an organic solution of ethyl 3-(4-fluorophenylamino)-3-oxopropanoate and stirred until the reaction was complete. The organic solvent in the reaction solution was spun dry and extracted, then the pH of the aqueous phase was adjusted to 7 with hydrochloric acid solution, extracted, and the organic layers were combined and dried and spun dry to produce 3-(4-fluorophenylamino)-3-oxopropanoic acid.
3-(4-fluorophenylaMino)-3-oxopropanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| AstaTech (Chengdu) Pharma. Co., Ltd. | 15928766785 15928766785 | wupengcheng@astatech.cn | China | 1998 | 55 |
| Taizhou Tongxin Bio-Tech Co., Ltd | 0523-86818997 18652728585 | sales@allyrise.com | China | 2987 | 60 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| SanoChem (Chengdu) Tech. Co., Ltd. | 28-87999436 02887999436 | sales@sano-chem.com | China | 3792 | 55 |
| Jinan Winwind Biological Technology Co., Ltd | 15153166971 | win-wind@hotmail.com | China | 97 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| Jinan Kabotang Biological Technology Co.,Ltd. | 0531-61320525 15866703830 | figo.gao@foxmail.com | China | 7601 | 58 |
| Zhaoqing Wanwei New Material Technology Co., Ltd. | 0755-1328880-4488 13049823633;13068786899;13288804488 | 13288804488@163.com | China | 623 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3925 | 58 |
| Beijing Minruida Technology Co., Ltd. | 010-82387566 | sales@mreda.com.cn | China | 19323 | 58 |
