tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate
- CAS No.
- 558442-96-9
- Chemical Name:
- tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate
- Synonyms
- 105471;tert-butyl N-(4-morpholinocyclohexyl)carbamate;tert-Butyl (trans-4-morpholinocyclohexyl)carbamate;tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate;(trans-4-morpholinecyclohexyl)aminomacetic acidtertbutyl ester;Carbamic acid, N-[trans-4-(4-morpholinyl)cyclohexyl]-, 1,1-dimethylethyl ester
- CBNumber:
- CB52684445
- Molecular Formula:
- C15H28N2O3
- Molecular Weight:
- 284.39
- MDL Number:
- MFCD27978480
- MOL File:
- 558442-96-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| tert-Butyl ((1r,4r)-4-morpholinocyclohexyl)-carbamate | 120887 | 5.00g | $1486 |
| tert-Butyl ((1r,4r)-4-morpholinocyclohexyl)-carbamate | 120887 | 10.00g | $2376 |
| tert-Butyl (trans-4-morpholinocyclohexyl)carbamate 95% | AA00E89W | 100mg | $127 |
| tert-Butyl (trans-4-morpholinocyclohexyl)carbamate 95% | AA00E89W | 250mg | $173 |
| tert-Butyl (trans-4-morpholinocyclohexyl)carbamate 95% | AA00E89W | 1g | $467 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 120887 | tert-Butyl ((1r,4r)-4-morpholinocyclohexyl)-carbamate | 558442-96-9 | 5.00g | $1486 | 2026-05-18 | Buy |
| Matrix Scientific | 120887 | tert-Butyl ((1r,4r)-4-morpholinocyclohexyl)-carbamate | 558442-96-9 | 10.00g | $2376 | 2026-05-18 | Buy |
| aablocks | AA00E89W | tert-Butyl (trans-4-morpholinocyclohexyl)carbamate 95% | 558442-96-9 | 100mg | $127 | 2026-05-28 | Buy |
| aablocks | AA00E89W | tert-Butyl (trans-4-morpholinocyclohexyl)carbamate 95% | 558442-96-9 | 250mg | $173 | 2026-05-28 | Buy |
| aablocks | AA00E89W | tert-Butyl (trans-4-morpholinocyclohexyl)carbamate 95% | 558442-96-9 | 1g | $467 | 2026-05-28 | Buy |
tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate Chemical Properties,Uses,Production
Synthesis
5414-19-7
177906-48-8
558442-96-9
The general procedure for the synthesis of tert-butyl (trans-4-morpholinocyclohexyl)carbamate from 2,2'-dibromodiethyl ether and tert-butyl trans-(4-aminocyclohexyl)carbamate was as follows: 21.43 g (0.1 mol) of tert-butyl N-(trans-4-aminocyclohexyl)carbamate was dissolved into 250 mL of N,N-dimethylformamide, followed by addition of 16.76 mL (0.12 mol) bis(2-bromoethyl) ether and 34.85 mL (0.25 mol) triethylamine. The reaction mixture was stirred at 70°C for 6 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate, and the organic layer was washed sequentially with aqueous sodium carbonate and saturated brine solution, and then dried over anhydrous sodium sulfate. The solvent was again removed by reduced pressure distillation and the residue was purified by silica gel column chromatography (elution gradient: from pure chloroform to chloroform/methanol=30/1) to give 19.92 g (70% yield) of tert-butyl (trans-4-morpholino cyclohexyl)carbamate.
References
[1] Patent: EP1775298, 2007, A1. Location in patent: Page/Page column 33-34
tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11680 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39021 | 58 |
| ChemShuttle, Inc. | 0510-83588313-811 18800520310 | sales@chemshuttle.com | China | 2999 | 62 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4742 | 55 |
| Shanghai JiYi Biotechnology Co. Ltd. | 13621943973 | sales@shjiyipharmatech.com | China | 1166 | 55 |
| Shanghai Uchem Inc. | 15618758386 15618758386 | sales3@myuchem.com | China | 1989 | 55 |
| ShangHai Wisacheam Pharmaceutical Co., Ltd. | 13817485796 | tim@wisacheampharm.com | China | 3680 | 58 |
| Wuxi KaideRui Pharmaceutical Technology Co., Ltd | 19906241957 | 1557216087@qq.com | China | 1853 | 55 |
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