Antcin B
- CAS No.
- 163597-25-9
- Chemical Name:
- Antcin B
- Synonyms
- Antcin B;Ergosta-8,24(28)-dien-26-oic acid, 4-methyl-3,7,11-trioxo-, (4α,5α)-
- CBNumber:
- CB52686090
- Molecular Formula:
- C29H40O5
- Molecular Weight:
- 468.63
- MDL Number:
- MOL File:
- 163597-25-9.mol
Antcin B Chemical Properties, Uses, Production
Uses
Antcin B is a SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) inhibitor. Antcin B binds to multiple key amino acid residues of 3CL Pro(such as Leu141, Asn142, Glu166, His163, etc.) through hydrogen bonds, salt bridges, and hydrophobic interactions, thereby inhibiting the activity of 3CL Pro, blocking the cleavage process of viral polyproteins, and suppressing the replication of the SARS-CoV-2 virus in host cells. Antcin B is promising for research of COVID-19[1].
References
[1] Dakpa G, et al. Antcin-B, a phytosterol-like compound from Taiwanofungus camphoratus inhibits SARS-CoV-2 3-chymotrypsin-like protease (3CLPro) activity in silico and in vitro. Sci Rep. 2023 Oct 10;13(1):17106. DOI:10.1038/s41598-023-44476-x
Antcin B Preparation Products And Raw materials
Raw materials
Preparation Products
Antcin B Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Jiangsu Yongjian Pharmaceutical Technology Co., Ltd | 17701422015 | 3582572959@qq.com | China | 990 | 58 |
| Hubei Danding Pharmaceutical Technology Co., Ltd | 17701422019 17701422019 | 181646821@qq.com | China | 2421 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
