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(E)-2-oxopropanal oxime

CAS No.
306-44-5
Chemical Name:
(E)-2-oxopropanal oxime
Synonyms
ISONITROSOACETONE;PYRUVALDOXIME;oximinoacetone;pyruvaldehydoxim;Acetone, isonitroso-;2-oxopropanal-1-oxime;3-hydroxyimino-aceton;3-hydroxyiminoacetone;monoizonitrozoacetone;PYRUVALDEHYDE 1-OXIME
CBNumber:
CB5272301
Molecular Formula:
C3H5NO2
Molecular Weight:
87.08
MDL Number:
MFCD00002123
MOL File:
306-44-5.mol
MSDS File:
SDS
Last updated:2026-05-28 05:18:25
Product description Number Pack Size Price
2-Oxopropanal 1-Oxime min. 95.0 % O0703 1G $57
2-Oxopropanal 1-Oxime min. 95.0 % O0703 5G $171
Isonitrosoacetone TRC-I821863-100MG 100mg $72
Propanal, 2-oxo-,1-oxime 95% AA0030L2 1g $24
Propanal, 2-oxo-,1-oxime 95% AA0030L2 5g $52

(E)-2-oxopropanal oxime Properties

Melting point 69°
Boiling point 160.87°C (rough estimate)
Density 1.0744
refractive index 1.4940 (estimate)
storage temp. Storage temp. -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka pK (25°) 8.39
color Brown
InChI InChI=1S/C3H5NO2/c1-3(5)2-4-6/h2,6H,1H3
InChIKey OVGLVOLWBBGQHS-UHFFFAOYSA-N
SMILES C(=NO)C(=O)C
FDA UNII U32V8CLT4W
EPA Substance Registry System Propanal, 2-oxo-, 1-oxime (306-44-5)

SAFETY

Risk and Safety Statements

(E)-2-oxopropanal oxime price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical O0703 2-Oxopropanal 1-Oxime min. 95.0 % 306-44-5 1G $57 2026-04-30 Buy
TCI Chemical O0703 2-Oxopropanal 1-Oxime min. 95.0 % 306-44-5 5G $171 2026-04-30 Buy
TRC TRC-I821863-100MG Isonitrosoacetone 306-44-5 100mg $72 2026-06-03 Buy
aablocks AA0030L2 Propanal, 2-oxo-,1-oxime 95% 306-44-5 1g $24 2026-05-28 Buy
aablocks AA0030L2 Propanal, 2-oxo-,1-oxime 95% 306-44-5 5g $52 2026-05-28 Buy
Product number Packaging Price Buy
O0703 1G $57 Buy
O0703 5G $171 Buy
TRC-I821863-100MG 100mg $72 Buy
AA0030L2 1g $24 Buy
AA0030L2 5g $52 Buy

(E)-2-oxopropanal oxime Chemical Properties,Uses,Production

Uses

(E)-2-oxopropanal oxime can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and pharmaceutical and chemical production processes.

Preparation

To a well-stirred, ice-cooled solution of 5.8 gm (0.1 mole) of acetone in 30 ml of glacial acetic acid is added dropwise a concentrated aqueous solution containing 15 gm of sodium nitrite. Stirring at 0°C is continued for 45 min, then 100 ml of water is added and the crude product is extracted with ether.
306-44-5 synthesis
The ether extracts are combined, washed repeatedly with 10 ml portions of water, and dried with sodium sulfate. The ether is evaporated off under reduced pressure and the residue is dried on a porous plate. After recrys-tallization from benzene, 6 gm (69%) of the product is isolated, m.p. 65°C.

Synthesis

3.png
under the condition of the ice, to 1000 ml three port successively added in the bottle KOH (58.35g, 1 . 16eq, 1 . 04mol) and 585 ml water, the reaction system is cooled to 0 °C, adding to the reaction system (103.61g, 1eq, 0.892mol), after stirring at room temperature add 24h; once again the reaction system is cooled to 0 °C, in the reaction system by adding NaNO2(71.76g, 1 . 16eq, 1 . 04mol), the reaction system to maintain 0 °C, to wherein the dropwise H2SO4(50%), the for PH 4-5 (adding sulphuric acid to the volume to the final system is PH), stir at room temperature 2h, this will produce a large amount of gas in the process, a white precipitate, then in to the system by adding NaOH (35%) solution, the for PH 9-10, finally in the reaction system by adding 100 ml of toluene, the organic phase and aqueous phase separation, is added to the aqueous phase H2SO4(50%) the adjusted to PH 5-6, ethyl acetate (3*100 ml) extraction, anhydrous sodium sulfate for drying, can be obtained turns on lathe does white solid 61 . 3g (yield 79%).

141-97-9
306-44-5
Synthesis of (E)-2-oxopropanal oxime from Ethyl acetoacetate

(E)-2-oxopropanal oxime Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-2-oxopropanal oxime Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Victorypharm Co.,Ltd.
+86-13916956214 sales@victory-pharm.com China 1298 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16505 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
Career Henan Chemica Co
+86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Suzhou Laing Biotechnology Co.,Ltd
+86-13004516015 +86-18149392822 christina@laingbiotec.com China 777 58
Zhengzhou Lingzhiyue Technology Co., Ltd
+86-0371-55074660 +86-13523716970 Lingzhiyue@aliyun.com China 3137 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501 product@acmec-e.com China 33301 58
Anhuyan (Hainan) Biotechnology Co., LTD
+86-18163349544 mollylucking@foxmail.com China 3000 58

View Lastest Price from (E)-2-oxopropanal oxime manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
isonitrosoacetone pictures 2026-07-02 isonitrosoacetone
306-44-5
$1.10-9.90 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
(E)-2-oxopropanal oxime; 1-Hydroxyimino-2-propanone pictures 2023-09-24 (E)-2-oxopropanal oxime; 1-Hydroxyimino-2-propanone
306-44-5
98% 500kg Suzhou Laing Biotechnology Co.,Ltd
ANTI-PYRUVIC ALDEHYDE 1-OXIME 2-oxopropionaldehyde 1-oxime PYRUVALDEHYDE 1-OXIME 98+% 2-OXO-PROPIONALDEHYDE OXIME Propanal, 2-oxo-, 1-oxime 1-(Hydroxyimino)acetone 1-Hydroxyimino-2-propanone Propane-1,2-dione 1-oxime 2-Propanone, 1-(hydroxyimino)- 2-Propanone, 1-isonitroso- 2-Propanone, isonitroso- Acetone, (hydroxyimino)- Acetone, 3-(hydroxyimino)- Acetone, isonitroso- 4-(hydroxyiMino)butan-2-one (1E)-2-oxopropanal oxime 1,2-propanedione,1-oxime 2-oxopropanal-1-oxime 3-hydroxyimino-aceton 3-hydroxyiminoacetone monoizonitrozoacetone oximinoacetone pyruvaldehydoxim PYRUVALDEHYDE 1-OXIME PYRUVALDOXIME (E)-2-oxopropanal oxime ISONITROSOACETONE 306-44-5 CH3COCHNOH