Isoprenaline hydrochloride
- CAS No.
- 51-30-9
- Chemical Name:
- Isoprenaline hydrochloride
- Synonyms
- ISOPROTERENOL HYDROCHLORIDE;ISOPRENALINE HCL;isuprel;Isovon;Isomenyl;Mistarel;euspiran;isadrine;Proterno;proternol
- CBNumber:
- CB5276844
- Molecular Formula:
- C11H18ClNO3
- Molecular Weight:
- 247.72
- MDL Number:
- MFCD00012603
- MOL File:
- 51-30-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 165-175 °C (dec.)(lit.) |
|---|---|
| Boiling point | 192°C (rough estimate) |
| Density | 1.2296 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | 2-8°C |
| solubility | Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. |
| form | White solid |
| color | White to Off-White |
| Water Solubility | Soluble |
| BRN | 3917363 |
| Stability | Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents. |
| InChI | InChI=1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H |
| InChIKey | IROWCYIEJAOFOW-UHFFFAOYSA-N |
| SMILES | C1(=CC=C(O)C(O)=C1)C(O)CNC(C)C.Cl |
| CAS DataBase Reference | 51-30-9(CAS DataBase Reference) |
| FDA UNII | DIA2A74855 |
| EPA Substance Registry System | Isoproterenol hydrochloride (51-30-9) |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H303-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | DO1925000 | |||||||||
| F | 3-8-10 | |||||||||
| HS Code | 29225090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Toxicity | LD50 oral in rabbit: 3070mg/kg | |||||||||
| NFPA 704 |
|
Isoprenaline hydrochloride price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2722 | Isoproterenol Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 51-30-9 | 250MG | $233 | 2026-04-30 | Buy |
| Sigma-Aldrich | I0599990 | Isoprenaline hydrochloride European Pharmacopoeia (EP) Reference Standard | 51-30-9 | 50 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | BP205 | Isoprenaline hydrochloride British Pharmacopoeia (BP) Reference Standard | 51-30-9 | 100MG | $296 | 2026-04-30 | Buy |
| Sigma-Aldrich | 420355 | Isoproterenol, Hydrochloride Phenethylamine derivative. | 51-30-9 | 100mg | $60.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1351005 | Isoproterenol hydrochloride United States Pharmacopeia (USP) Reference Standard | 51-30-9 | 125mg | $412 | 2026-04-30 | Buy |
Isoprenaline hydrochloride Chemical Properties, Uses, Production
Description
Isoprenaline hydrochloride is an FDA-approved injectable drug that is the hydrochloride form of isoprenaline and is used as a bronchodilator, adrenergic beta agonist, cardiotonic, and sympathomimetic. Selective beta-adrenergic agonist that increases cytoplasmic cAMP. promotes glycogenolysis and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit tracheal cells via nitric oxide production. In addition, it can be used as an inducer in an experimental rat model of induced myocardial infarction[1].
Chemical Properties
White or almost white, crystalline powder.
Uses
Isoproterenol is a non-selective beta-adrenergic agonist. Isoproterenol is used in the treatment of bradycardia; bronchodilator.
Uses
Isoproterenol hydrochloride is used as a selective β-adrenergic agonist, increases cytosolic cAMP.
Definition
ChEBI: DL-Isoprenaline hydrochloride is a member of catechols.
brand name
Isuprel (Hospira); Isuprel (Sanofi Aventis); Vapo- ISO (Fisons).
General Description
Isoproterenol hydrochloride is an odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air. (NTP, 1992)
Air & Water Reactions
May be sensitive to exposure to air and light. . Water soluble.
Reactivity Profile
An acid organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Health Hazard
SYMPTOMS: Symptoms of exposure to Isoprenaline hydrochloride may include tremors, nervous apprehension, palpitations of the heart, epigastric distress, cardiac arrhythmias, myocardial necrosis, cardiac arrest, tachycardia, headache, flushing of the skin, anginal pain, nausea, dizziness, weakness, and sweating.
Fire Hazard
Flash point data for Isoprenaline hydrochloride are not available. Isoprenaline hydrochloride is probably combustible.
Biological Activity
Standard selective β -adrenoceptor agonist; vasorelaxant and bronchodilator. Activation of β 2 receptors activates downstream PKA and ERK, and may stimulate NO-mediated endothelium-dependent smooth muscle relaxation. Active in vivo . Also available as part of the β -Adrenoceptor Agonist Tocriset™ and Mixed Adrenergic Tocriset™ .
Biochem/physiol Actions
β-adrenoceptor agonist; increases cytosolic cAMP.
storage
Store at RT
References
[1] FANG WANG. Fucoxanthin averts isoprenaline hydrochloride-induced myocardial infarction in rats[J]. Pharmacognosy Magazine, 2020, 16 1: 214-220. DOI:10.4103/pm.pm\_357\_19.
Isoprenaline hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Yuantai Pharmaceutical Co.,Ltd | 0531-69959492 18560053868 | 85349064@qq.com | China | 144 | 58 |
| Shandong Jihao Biotechnology Co., Ltd. | 0531-69958659 15668363232 | 8598038@qq.com | China | 46 | 58 |
| Jinan Shengqi Pharmaceutical Co., Ltd | 0531-82687819 15610111696 | xgc01@orgachem.com | China | 176 | 58 |
| Jinan Yuantai Pharmaceutical Co.,Ltd | 0531-69959492 18366108822 | 85633700@qq.com | China | 80 | 55 |
| Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 4000862158 18117107507 | vip@med-life.cn | China | 4999 | 58 |
| Zhejiang Boxiao Bio-Pharmaceutical Co., Ltd. | +86-571-63280982 | Helena_Huang@bx-biopharm.com | China | 47 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
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- Apr 10,2026
View Latest Price from Isoprenaline hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-14 | Isoprenaline hydrochloride
51-30-9
|
$100.00 | 1KG | 99% | 1000 KG | HANGZHOU DINGYAN CHEM CO.,LTD | |
 |
2026-08-20 | Isoprenaline hydrochloride USP/EP/BP
51-30-9
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-08-20 | Isoprenaline hydrochloride
51-30-9
|
$33.00 | 99.89% | 10g | TargetMol Chemicals Inc. |
-
- Isoprenaline hydrochloride
51-30-9
- $100.00
- 99%
- HANGZHOU DINGYAN CHEM CO.,LTD
-
- Isoprenaline hydrochloride USP/EP/BP
51-30-9
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Isoprenaline hydrochloride
51-30-9
- $33.00
- 99.89%
- TargetMol Chemicals Inc.
