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N-Cbz-1,2-diaMinoethane

N-Cbz-1,2-diaMinoethane structure

CAS No.: 72080-83-2

Chemical Name:: N-Cbz-1,2-diaMinoethane

Synonyms: N-Cbz-ethylenediamine;benzyl 2-aminoethylcarbamate;(2-AMino-ethyl)-carbaMic acid benzyl ester;Z-EDA HCL;Z-NH(CH2)2NH2 HCL;TIMTEC-BB SBB003280;Z-DIAMINOETHANE HCL;Z-1,2-DIAMINOETHANE HCL;N-CBZ-1,2-DIAMINOETHANE;N1-Cbz-1,2-ethanediamine

CBNumber:: CB5302152

Molecular Formula:: C10H14N2O2

Molecular Weight:: 194.23

MDL Number:: MFCD02094510

MOL File:: 72080-83-2.mol

MSDS File:: SDS

Last updated:2026-05-28 02:38:06

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N-Cbz-1,2-diaMinoethane Properties

Melting point	169-172 °C(lit.)
Boiling point	188 °C(Press: 4.5 Torr)
Density	1.134±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
pka	12.19±0.46(Predicted)
Appearance	Colorless to light pink Liquid
InChI	InChI=1S/C10H14N2O2/c11-6-7-12-10(13)14-8-9-4-2-1-3-5-9/h1-5H,6-8,11H2,(H,12,13)
InChIKey	QMMFTRJQCCVPCE-UHFFFAOYSA-N
SMILES	C(OCC1=CC=CC=C1)(=O)NCCN

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
F	3

N-Cbz-1,2-diaMinoethane price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B6489	Benzyl (2-Aminoethyl)carbamate	72080-83-2	1G	$60	2026-04-30	Buy
TCI Chemical	B6489	Benzyl (2-Aminoethyl)carbamate	72080-83-2	5G	$181	2026-04-30	Buy
Biosynth	FD111184	N-1-Z-1,2-diaminoethane·HCl	72080-83-2	5g	$900	2026-06-04	Buy
Biosynth	FD111184	N-1-Z-1,2-diaminoethane·HCl	72080-83-2	2g	$900	2026-06-04	Buy
Biosynth	FD111184	N-1-Z-1,2-diaminoethane·HCl	72080-83-2	1g	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
B6489	1G	$60	Buy
B6489	5G	$181	Buy
FD111184	5g	$900	Buy
FD111184	2g	$900	Buy
FD111184	1g	$900	Buy

N-Cbz-1,2-diaMinoethane Chemical Properties, Uses, Production

Synthesis

501-53-1

107-15-3

72080-83-2

Dichloromethane (100 mL), ethylenediamine (39 mL, 0.58 mol) and potassium carbonate (32.4 g, 0.23 mol) were added to a 500 mL three-necked flask under nitrogen protection. The temperature of the reaction system was controlled at -5 to 0°C and a solution of benzyl chloroformate (20.0 g, 0.12 mol) in dichloromethane (100 mL) was slowly added dropwise under stirring. The dropwise addition process was completed in about 1 hour, followed by continued stirring of the reaction for 2 hours at room temperature. Upon completion of the reaction, the reaction mixture was washed with water (200 mL x 2). The organic layer was separated and dried over anhydrous sodium sulfate (10 g). The organic layer was concentrated under reduced pressure to give a light yellow foamy product of 23.4 g. To the residue, ethyl acetate (80 mL) was added and stirred at room temperature until completely dissolved, then petroleum ether (80 mL) was added dropwise to precipitate a white solid (N-Cbz-1,2-diaminoethane). The solid was collected by filtration, and the mother liquor was concentrated to obtain 15.1 g of light yellow oil, the total yield was 66.5%.

References

[1] Chemical Communications, 2017, vol. 53, # 52, p. 7088 - 7091
[2] New Journal of Chemistry, 2013, vol. 37, # 7, p. 1895 - 1905
[3] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 5, p. 550 - 555
[4] Chemistry - A European Journal, 2011, vol. 17, # 19, p. 5251 - 5255
[5] Synthesis, 1984, # 12, p. 1032 - 1033

N-Cbz-1,2-diaMinoethane Preparation Products And Raw materials

Raw materials

Benzyl N-(2-aminoethyl)carbamate hydrochloride benzyl 2-azidoethylcarbamate N-(2-aminoethyl)methanesulfonamide N-(Benzyloxycarbonyloxy)succinimide Ethylenediamine

Bromophenol Blue Benzyl chloroformate Potassium carbonate Dichloromethane

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Preparation Products

N-Cbz-1,2-diaMinoethane Suppliers

Global Suppliers ( 119)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Renshi Pharmatech Co., LTD	021-61150625 18521367657	info@renshipharma.com	China	184	55
Zepeptide Biotechnology (Shijiazhuang) Co., LTD	13383293380 18032131480	649498984@qq.com	China	78	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Shanghai Targsense Scientific Co., Ltd.	18916626092	targsense@qq.com	China	110	65
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.	85114309 18982182443	yangli@happysyn.com	China	2284	55

Supplier	Advantage
Shanghai Renshi Pharmatech Co., LTD	55
Zepeptide Biotechnology (Shijiazhuang) Co., LTD	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Shanghai Targsense Scientific Co., Ltd.	65
Jia Xing Isenchem Co.,Ltd	66
Accela ChemBio Co.,Ltd.	64
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.	55

View Latest Price from N-Cbz-1,2-diaMinoethane manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-06-30	N-Cbz-1,2-diaMinoethane 72080-83-2		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
	2020-01-09	BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE 72080-83-2	$6.68	1KG	97%-99%	1kg-1000kg	Career Henan Chemical Co

N-Cbz-1,2-diaMinoethane
72080-83-2
98.0%
Shaanxi Dideu New Materials Co. Ltd

BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE
72080-83-2
$6.68
97%-99%
Career Henan Chemical Co

N-Cbz-1,2-diaMinoethane Spectrum

N-Cbz-1,2-diaMinoethane(72080-83-2)¹HNMR

72080-83-2 (N-Cbz-1,2-diaMinoethane) Related Search:

Benzyl N-(2-aminoethyl)carbamate hydrochloride Z-Val-Phe-OH Z-Pro-NH2 Ethylenediamine N-Cbz-Val-Tyr methyl ester

Z-Ala-Gly-Gly-OH Z-Ile-Gly-OH Z-Ala-Phe-OH Z-Phe-Pro-NH2 Z-Ile-Phe-OH

Z-Pro-D-Leu-OH Z-Val-Ala-OH Z-Pro-Met-OH Z-Tyr-Tyr-OH Z-DL-Ala-Gly-OH

Z-Pro-Ile-OH Z-Ile-Ala-OH Z-Leu-Gly-Gly-OH

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N-1-CARBOBENZOXY-1,2-DIAMONOETHANE HYDROCHLORIDE N-1-Z-1,2-DIAMINOETHANE HCL N-(2-AMINOETHYL)CARBAMIC ACID BENZYL ESTER HYDROCHLORIDE N-Cbz-ethylenediamine hydrochloride benzyl 2-aminoethylcarbamate (2-AMino-ethyl)-carbaMic acid benzyl ester Z-NH(CH2)2NH2 HCL Z-1,2-DIAMINOETHANE HCL Z-EDA HCL Z-DIAMINOETHANE HCL TIMTEC-BB SBB003280 BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE CarbaMic acid,N-(2-aMinoethyl)-, phenylMethyl ester N-Z-1,2-DIAMINOETHANE HYDROCHLORIDE N-Z-ETHYLENEDIAMINE HYDROCHLORIDE N-CARBOBENZOXY-1,2-DIAMINOETHANE HYDROCHLORIDE N-CBZ-1,2-DIAMINOETHANE HYDROCHLORIDE N1-BENZYLOXYCARBONYL-ETHYLENEDIAMINE HYDROCHLORIDE N1-Cbz-1,2-ethanediamine N-CBZ-1,2-DIAMINOETHANE N-Benzyloxycarbonylethylenediamine N-Cbz-ethylenediamine N-Benzyloxycarbonyl-1,2-diaminoethane 72080-83-2 N-Cbz-diaminoalkanes Monoprotected Diaminoalkanes Building Blocks Protected Amines Organic Building Blocks Nitrogen Compounds