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2-(Aminomethyl)-1-ethylpyrrolidine

2-(Aminomethyl)-1-ethylpyrrolidine Structure
2-(Aminomethyl)-1-ethylpyrrolidine structure
CAS No.
26116-12-1
Chemical Name:
2-(Aminomethyl)-1-ethylpyrrolidine
Synonyms
Sulpiride impurity A CRS;Amisulpride EP Impurity A;n-ethyl-2-methylaminopyrrolidine;N-ETHYL-2-AMINOMETHYLPYRROLIDINE;1-ethylpyrrolidin-2-ylmethylamine;)-1-ethyL;Refer to S-402;Sulpiride EP Impurity A;Sulpiride Impurity A(EP);1-Ethyl-2-pyrrolidinemethylamine
CBNumber:
CB5307995
Molecular Formula:
C7H16N2
Molecular Weight:
128.22
MDL Number:
MFCD00003178
MOL File:
26116-12-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:10:53
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2-(Aminomethyl)-1-ethylpyrrolidine Properties

Boiling point 58-60 °C16 mm Hg(lit.)
Density 0.884 g/mL at 25 °C(lit.)
refractive index n20/D 1.4670(lit.)
Flash point 135 °F
storage temp. 2-8°C
solubility Chloroform (Sparingly), Methanol (Sparingly)
pka 10.04±0.40(Predicted)
form Liquid
color Clear yellow
InChI InChI=1S/C7H16N2/c1-2-9-5-3-4-7(9)6-8/h7H,2-6,8H2,1H3
InChIKey UNRBEYYLYRXYCG-UHFFFAOYSA-N
SMILES N1(CC)CCCC1CN
LogP 0.433 (est)
CAS DataBase Reference 26116-12-1(CAS DataBase Reference)
FDA UNII K2U95PPN4Z
NIST Chemistry Reference 2-Pyrrolidinemethanamine, 1-ethyl-(26116-12-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36
RIDADR  UN 1993 3/PG 3
WGK Germany  3
HazardClass  3.2
PackingGroup  III
HS Code  29339900
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
REACH Registrations Active

2-(Aminomethyl)-1-ethylpyrrolidine price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 655600 2-(Aminomethyl)-1-ethylpyrrolidine 97% 26116-12-1 5g $110 2026-04-30 Buy
Sigma-Aldrich S2191000 Sulpiride impurity A European Pharmacopoeia (EP) Reference Standard 26116-12-1 20 mg $241 2026-04-30 Buy
Sigma-Aldrich 655600 2-(Aminomethyl)-1-ethylpyrrolidine 97% 26116-12-1 25g $519 2026-04-30 Buy
TCI Chemical A2556 2-(Aminomethyl)-1-ethylpyrrolidine >98.0%(GC)(T) 26116-12-1 5g $39 2026-04-30 Buy
TCI Chemical A2556 2-(Aminomethyl)-1-ethylpyrrolidine >98.0%(GC)(T) 26116-12-1 25g $113 2026-04-30 Buy
Product number Packaging Price Buy
655600 5g $110 Buy
S2191000 20 mg $241 Buy
655600 25g $519 Buy
A2556 5g $39 Buy
A2556 25g $113 Buy

2-(Aminomethyl)-1-ethylpyrrolidine Chemical Properties,Uses,Production

Chemical Properties

clear yellow liquid

Uses

2-(Aminomethyl)-1-ethylpyrrolidine is used as a reagent in the synthesis of S-Desethyl S-Methyl Amisulpride (D289595)

Synthesis

1-Ethyl-1H-pyrrole-2-carbaldehyde

2167-14-8

2-(Aminomethyl)-1-ethylpyrrolidine

26116-12-1

General procedure for the synthesis of N-ethyl-2-aminomethylpyrrolidine from 1-ethyl-1H-pyrrole-2-carboxaldehyde: 60 g of 1-ethyl-1H-pyrrole-2-carboxaldehyde was added to an autoclave, and 5 g of palladium-carbon catalyst at a mass percent concentration of 5% and 15 g of liquid ammonia were added to carry out hydrogenation and reductive amination reactions. The reaction conditions were hydrogen pressure of 35 kg and temperature of 95°C. After completion of the reaction, the system was cooled, the gas was expelled, and filtration was carried out. The filter cake was washed with methanol, and the filtrate and washings were combined to recover methanol. Finally, the target product N-ethyl-2-aminomethylpyrrole was obtained by purification via decompression distillation in a yield of 53.7 g and 86%. The reaction equation was as follows:

References

[1] Patent: CN107973735, 2018, A. Location in patent: Paragraph 0017; 0027-0029

2-(Aminomethyl)-1-ethylpyrrolidine synthesis

2167-14-8
26116-12-1
Synthesis of 2-(Aminomethyl)-1-ethylpyrrolidine from 1-Ethyl-1H-pyrrole-2-carbaldehyde

2-(Aminomethyl)-1-ethylpyrrolidine Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Tetrahydrofurfuryl alcohol 1-Ethyl-1H-pyrrole-2-carbaldehyde

Preparation Products

Remoxipride Levosulpiride AMisulpride IMpurity D Amisulpride

2-(Aminomethyl)-1-ethylpyrrolidine Suppliers

Global( 437)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd 027-59599241 18871490274 1400878000@qq.com China 9506 58
Shanghai Taijilin Industrial Co., Ltd. 02150630626 17717886015 kate@tajilin.com China 1340 58
Hubei yongkuo Technology Co., Ltd 027-59223108 15972152991 1248580099@qq.com China 9910 58
NANJING CHEMFIRST CO.,LTD. 025-87780427 15850602248 info@chemfs.com China 16 58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 027-027-59308705 18871579363 1248680011@qq.com China 9279 58
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 6065 65
Hubei Hengjie Chemical Co., Ltd 15623078521; 15623078521 1836463726@qq.com China 3578 58
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd 58
Shanghai Taijilin Industrial Co., Ltd. 58
Hubei yongkuo Technology Co., Ltd 58
NANJING CHEMFIRST CO.,LTD. 58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 58
Shanghai Qiao Chemical Science Co., Ltd 65
Hubei Hengjie Chemical Co., Ltd 58
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62

View Lastest Price from 2-(Aminomethyl)-1-ethylpyrrolidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(Aminomethyl)-1-ethylpyrrolidine pictures 2026-06-30 2-(Aminomethyl)-1-ethylpyrrolidine
26116-12-1
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2- (Aminomethyl) -1-Ethylpyrrolidine pictures 2026-05-28 2- (Aminomethyl) -1-Ethylpyrrolidine
26116-12-1
 $10.00 1KG 98% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
2-(Aminomethyl)-1-ethylpyrrolidine pictures 2026-02-02 2-(Aminomethyl)-1-ethylpyrrolidine
26116-12-1
 $1.00 160KG 99.0%GC 2000tons Shaanxi Dideu Medichem Co. Ltd

2-(Aminomethyl)-1-ethylpyrrolidine Spectrum

2-(Aminomethyl)-1-ethylpyrrolidine(26116-12-1)MS2-(Aminomethyl)-1-ethylpyrrolidine(26116-12-1)1HNMR2-(Aminomethyl)-1-ethylpyrrolidine(26116-12-1)IR1

26116-12-1(2-(Aminomethyl)-1-ethylpyrrolidine)Related Search:

Ethyl cellulose Ethyl acetate 2,5-Dimethylpyrrolidine Hexamethyldisilazane Pyrrolidine
Ethyl acrylate Ethylparaben 1-Methylpyrrolidine N-Methyl-2-pyrrolidone Ethyl formate
Ethylbenzene Ethanol Chloroethane Actinomycin D N-Acetyl-L-prolinamide
Methyl-2-pyrrolidone (R)-(+)-2-Aminomethyl-1-ethylpyrrolidine Diethyl ether

1of4

(1-Ethyl-2-pyrrolidinyl)methanamine 1-Ethyl-2-(aminomethyl)pyrrolidine 1-Ethyl-2-pyrrolidinemethylamine 2-(Aminomethyl)-N-ethylpyrrolidine AMisulpride IMpurity A (Sulpiride IMpurity A) Sulpiride IMpurity A (AMisulpride IMpurity A) Pyrrolidine, 2-(aminomethyl)-1-ethyl- 2-(Aminomethyl)-1-ethylpyrrolidine 97% Sulpiride Impurity A(EP) [(2RS)-1-ethylpyrrolidin-2- yl]methanamine Sulpiride Impurity 1（Sulpiride EP Impurity A） N-Ethyl-2-Aminomethyl Pirrolidine Sulpiride EP Impurity A Amisulpride Impurity 1（Amisulpride EP Impurity A) Amisulpride EP Impurity A 2-(AMINOMETHYL)-1-ETHYLPYRROLIDINE 2-PYRROLIDINEMETHANAMINE, 1-ETHYL-, (2S)- N-ETHYL-ALPHA-AMINOMETHYL PYRROLIDINE S(-)-1-ETHYL-2-(AMINOMETHYL)PYRROLIDINE S-(-)N-ETHYL-A-AMINOMETHYL-PYRROLIDINE S-(-)-N-ETHYL-ALPHA-(AMINOMETHYL)PYRROLIDINE 2-(Aminomethyl)-1-ethylpyrrolidine/N-ethyl-2-aminomethyl pyrrolidine N-Ethyl-2-Aminoethyl Pyrrolidine 1-ethylpyrrolidin-2-ylmethylamine S-(-)N-METHYL-A-AININOMETHYL-PYPROLIDINE [(1-Ethyl-2-pyrrolidinyl)methyl]amine 1-Ethylpyrrolidine-2-methanamine 2-(Aminomethyl)-1-ethylpyrrolidine,95% C-(1-Ethyl-pyrrolidin-2-yl)-methylamine 2-(AMinoMethyl)-1-ethylpyrrolidine, 95% 10GR 2-(AMinoMethyl)-1-ethylpyrrolidine, 95% 50GR N-Ethyl-2-aMinoMethyl pyrrollidine 2-PyrrolidineMethanaMine,1-ethyl- (2RS)-1-[ETHYLPYRROLIDINE-2-YL]-METHANAMINE Amisulpride EP Impurity A (Sulpiride EP Impurity A) Sulpiride EP Impurity A (Amisulpride EP Impurity A) 2-(Aminomethyl)-1-ethylpyrrolidine (26116-12-1) 2-(Aminomethyl)-1-ethylpyrrolidine (CAS : 26116-12-1) 2-(Aminomethyl)-1-ethylpyrrolidine > [(2RS)-1-Ethylpyrrolidin-2-yl]metha Sulpiride impurity A CRS )-1-ethyL 1-Ethyl-2-aminomethyl pyrrolidine (EAP) Amisulpride EP impurity AQ: What is Amisulpride EP impurity A Q: What is the CAS Number of Amisulpride EP impurity A Q: What is the storage condition of Amisulpride EP impurity A Q: What are the applications of Amisulpride EP impurity A a . [(2RS)-1-e th ylpyrroli d i n-2-yl]me th a na mi ne , (Z)-[5-fluoro-2-methyl-1-[4-methylsulfanyl)benzylidene]-1H-inden-3-yl]acetic acid Refer to S-402 N-ETHYL-2-AMINOMETHYL PYRROLIDINE (OTHER DETAIL AS PER INVOICE) 2-(Aminomethyl)-1-ethylpyrrolidine - [A15585] 2-(Aminomethyl)-1-Ethylpyrrolidine 2-()-1- n-ethyl-2-methylaminopyrrolidine N-ETHYL-2-AMINOMETHYLPYRROLIDINE 26116-12-1 26161-12-1 C7H16N2 Pyrrolidines Heterocyclic Building Blocks Chiral Building Blocks