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ChemicalBook >> CAS DataBase List >>(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Structure
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole structure
CAS No.
681490-91-5
Chemical Name:
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole
Synonyms
Deflazacort Impurity 14;Delamanid Diol Impurity;(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole;1,2-Propanediol, 3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-, (2R)-
CBNumber:
CB53154143
Molecular Formula:
C7H10ClN3O4
Molecular Weight:
235.62
MDL Number:
MFCD30741734
MOL File:
681490-91-5.mol
Last updated:2023-05-15 10:44:02
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(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Properties

Boiling point 515.1±60.0 °C(Predicted)
Density 1.61±0.1 g/cm3(Predicted)
solubility soluble in Chloroform, DCM
pka 13.48±0.29(Predicted)
form Solid
color Off-White

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C367620 (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol 681490-91-5 25mg $385 2021-12-16 Buy
Medical Isotopes, Inc. 44480 (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol 681490-91-5 10mg $675 2021-12-16 Buy
Product number Packaging Price Buy
C367620 25mg $385 Buy
44480 10mg $675 Buy

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Chemical Properties, Uses, Production

Uses

(2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

DE-7

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4578 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4372 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20027 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016; 18162595016 3287908757@qq.com China 9111 58
Supplier Advantage
Lynnchem 58
Hubei Yangxin Medical Technology Co., Ltd. 55
Novachemistry 58
Suzhou Meishi Biotechnology Co., Ltd. 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 58
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole 1,2-Propanediol, 3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-, (2R)- Delamanid Diol Impurity Deflazacort Impurity 14 681490-91-5