ChemicalBook >> CAS DataBase List >>Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate structure

CAS No.: 82419-34-9

Chemical Name:: Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Synonyms: Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate;"(S)-ethyl 8,9-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate";9, 10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester;ethyl 6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylate

CBNumber:: CB53161983

Molecular Formula:: C15H13F2NO4

Molecular Weight:: 309.26

MDL Number:: MFCD00498285

MOL File:: 82419-34-9.mol

Last updated:2025-07-24 18:13:53

Product description	Number	Pack Size	Price
Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate	2845CL	100mg	$109
Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate	2845CL	250mg	$139
Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate	82419349	250mg	$151.2
Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 97%	A419532	1g	$252
Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 97%	CD11051712	1g	$347

Request For Quotation

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Properties

Melting point	261 °C(Solv: ethanol (64-17-5))
Boiling point	442.2±45.0 °C(Predicted)
Density	1.43±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	-3.62±0.60(Predicted)

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	2845CL	Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate	82419-34-9	100mg	$109	2021-12-16	Buy
AK Scientific	2845CL	Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate	82419-34-9	250mg	$139	2021-12-16	Buy
Alichem	82419349	Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate	82419-34-9	250mg	$151.2	2021-12-16	Buy
Ambeed	A419532	Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 97%	82419-34-9	1g	$252	2021-12-16	Buy
Crysdot	CD11051712	Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 97%	82419-34-9	1g	$347	2021-12-16	Buy

Product number	Packaging	Price	Buy
2845CL	100mg	$109	Buy
2845CL	250mg	$139	Buy
82419349	250mg	$151.2	Buy
A419532	1g	$252	Buy
CD11051712	1g	$347	Buy

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Chemical Properties,Uses,Production

Synthesis

74-96-4

82419-35-0

82419-34-9

The general procedure for the synthesis of ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate from ethyl bromide and fluorozinecarboxylic acid was as follows: 40 g of fluorozinecarboxylic acid was suspended in 200 mL of N,N-dimethylformamide, and ethyl bromide and 21.6 g of potassium carbonate were subsequently added to form a white suspension. The reaction mixture was stirred at 50 °C for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to collect 60 g of white solid. The solid was dissolved in a solvent mixture of 200 mL of dichloromethane and 200 mL of methanol and stirred at 40 °C. After filtration, the undissolved solid was dissolved again in a solvent mixture of 200 mL of dichloromethane and 200 mL of methanol, stirred at 40°C and filtered. The filtrates were combined and concentrated and dried by rotary evaporator. To the dried product, 300 mL of ether was added, stirred at room temperature and filtered to obtain a white solid, i.e., target compound II.

References

[1] Patent: CN107586302, 2018, A. Location in patent: Paragraph 0022; 0023; 0024

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Bromoethane Oxygen-fluorine acid Potassium carbonate N,N-Dimethylformamide

Preparation Products

Ofloxacin

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Suppliers

Global( 29)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15080	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Quality Control Solutions Ltd.	66853366 13670046396	sales@chem-strong.com	China	18390	56
parabiochem	025-83453382-8005	sale@parabiochem.com	China	9595	55
ShangHai Biochempartner Co.,Ltd	177-54423994 17754423994	2853530910@QQ.com	China	8000	62
Aikon International Limited	025-66061636 18013972705	qqyang@aikonchem.com	China	15813	58

Supplier	Advantage
career henan chemical co	58
Career Henan Chemica Co	58
AFINE CHEMICALS LIMITED	58
Henan Fengda Chemical Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	58
Quality Control Solutions Ltd.	56
parabiochem	55
ShangHai Biochempartner Co.,Ltd	62
Aikon International Limited	58

View Lastest Price from Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-13	Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 82419-34-9	US $9.80 / KG	1KG	≥98%	20 tons	Career Henan Chemical Co

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
82419-34-9
US $9.80 / KG
≥98%
Career Henan Chemical Co

82419-34-9(Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate)Related Search:

Ofloxacin EP Impurity C OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID) Ofloxacin OFLOXACIN N-OXIDE (MIXTURE OF DIASTEREOMERS) 9-Piperazino Ofloxacin

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 9, 10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester "(S)-ethyl 8,9-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate" ethyl 6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylate 82419-34-9