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ChemicalBook >> CAS DataBase List >>Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Structure
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate structure
CAS No.
82419-34-9
Chemical Name:
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
Synonyms
Oxyfluoro cyclized esters;Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate;"(S)-ethyl 8,9-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate";9, 10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester;ethyl 6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylate
CBNumber:
CB53161983
Molecular Formula:
C15H13F2NO4
Molecular Weight:
309.26
MDL Number:
MFCD00498285
MOL File:
82419-34-9.mol
MSDS File:
SDS
Last updated:2026-05-28 03:59:54
Request For Quotation

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Properties

Melting point 261 °C(Solv: ethanol (64-17-5))
Boiling point 442.2±45.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka -3.62±0.60(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ACHEMBLOCK AD271550 Ethyl 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 95% 82419-34-9 100MG $805 2026-05-27 Buy
ACHEMBLOCK AD271550 Ethyl 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 95% 82419-34-9 250MG $1450 2026-05-27 Buy
ACHEMBLOCK AD271550 Ethyl 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 95% 82419-34-9 1G $3350 2026-05-27 Buy
Crysdot CD11051712 Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 97% 82419-34-9 1g $347 2026-05-26 Buy
AK Scientific 2845CL Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 82419-34-9 100mg $109 2021-12-16 Buy
Product number Packaging Price Buy
AD271550 100MG $805 Buy
AD271550 250MG $1450 Buy
AD271550 1G $3350 Buy
CD11051712 1g $347 Buy
2845CL 100mg $109 Buy

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Chemical Properties,Uses,Production

Synthesis

Bromoethane

74-96-4

Oxygen-fluorine acid

82419-35-0

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

82419-34-9

The general procedure for the synthesis of ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate from ethyl bromide and fluorozinecarboxylic acid was as follows: 40 g of fluorozinecarboxylic acid was suspended in 200 mL of N,N-dimethylformamide, and ethyl bromide and 21.6 g of potassium carbonate were subsequently added to form a white suspension. The reaction mixture was stirred at 50 °C for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to collect 60 g of white solid. The solid was dissolved in a solvent mixture of 200 mL of dichloromethane and 200 mL of methanol and stirred at 40 °C. After filtration, the undissolved solid was dissolved again in a solvent mixture of 200 mL of dichloromethane and 200 mL of methanol, stirred at 40°C and filtered. The filtrates were combined and concentrated and dried by rotary evaporator. To the dried product, 300 mL of ether was added, stirred at room temperature and filtered to obtain a white solid, i.e., target compound II.

References

[1] Patent: CN107586302, 2018, A. Location in patent: Paragraph 0022; 0023; 0024

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Bromoethane Oxygen-fluorine acid Potassium carbonate N,N-Dimethylformamide

Preparation Products

Ofloxacin

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Suppliers

Global( 30)Suppliers
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Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
parabiochem 025-83453382-8005 sale@parabiochem.com China 9577 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Jinan Feiteng Pharmaceutical Technology Co., Ltd. 15589964716; 15253102672@163.com China 211 58
Zhengzhou Acme Chemical Co., Ltd. 0371-63315541 13323832564 1443871971@qq.com China 9898 58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. 18081075745 chemflowtech@sina.com China 1883 58
Dideu Industries Group Limited +8617392712697 1022@dideu.com China 29091 58
AFINE CHEMICALS LIMITED +86-571-85134551 +86-18958018566 info@afinechem.com China 15030 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Supplier Advantage
Quality Control Solutions Ltd. 56
parabiochem 55
ShangHai Biochempartner Co.,Ltd 62
Aikon International Limited 58
Jinan Feiteng Pharmaceutical Technology Co., Ltd. 58
Zhengzhou Acme Chemical Co., Ltd. 58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. 58
Dideu Industries Group Limited 58
AFINE CHEMICALS LIMITED 58
Career Henan Chemica Co 58

View Lastest Price from Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate manufacturers

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Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate pictures 2020-01-13 Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
82419-34-9
 $9.80 1KG ≥98% 20 tons Career Henan Chemical Co

82419-34-9(Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate)Related Search:

Ofloxacin EP Impurity C OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID) Ofloxacin OFLOXACIN N-OXIDE (MIXTURE OF DIASTEREOMERS) 9-Piperazino Ofloxacin
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 9, 10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester "(S)-ethyl 8,9-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate" ethyl 6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylate Oxyfluoro cyclized esters 82419-34-9