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ChemicalBook >> CAS DataBase List >>2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine Structure
2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine structure
CAS No.
1416740-16-3
Chemical Name:
2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine
Synonyms
2-BROMO-7-NITRO-5H-PYRROLO[3,2-B]PYRAZINE;2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine;5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-7-nitro-
CBNumber:
CB53169196
Molecular Formula:
C6H3BrN4O2
Molecular Weight:
243.02
MDL Number:
MFCD29110946
MOL File:
1416740-16-3.mol
MSDS File:
SDS
Last updated:2026-05-28 04:16:20
Request For Quotation

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine Properties

Density 2.088±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 7.54±0.50(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 308804 2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine 1416740-16-3 100.00mg $58 2026-05-19 Buy
Matrix Scientific 308804 2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine 1416740-16-3 250.00mg $119 2026-05-19 Buy
Matrix Scientific 308804 2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine 1416740-16-3 1.00g $291 2026-05-19 Buy
Synthonix B41883 2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine 97% 1416740-16-3 100mg $117 2026-05-06 Buy
Synthonix B41883 2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine 97% 1416740-16-3 250mg $130 2026-05-06 Buy
Product number Packaging Price Buy
308804 100.00mg $58 Buy
308804 250.00mg $119 Buy
308804 1.00g $291 Buy
B41883 100mg $117 Buy
B41883 250mg $130 Buy

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine Chemical Properties, Uses, Production

Synthesis

2-Amino-3,5-dibromopyrazine

24241-18-7

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine

1416740-16-3

Step 3: Synthesis of 2-bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine 2-Bromo-5H-pyrrolo[2,3-b]pyrazine (20 g, 101.0 mmol) was dissolved in pre-cooled concentrated sulfuric acid (140.0 mL) to form a bright orange solution. Concentrated nitric acid (12.73 g, 8.470 mL, 202.0 mmol) was slowly added dropwise over a period of 30 min under stirring conditions and ensuring that the temperature of the reaction was maintained below 10 °C (the color of the solution gradually changed to a clear red). After the dropwise addition was completed, the reaction mixture was removed from the ice bath and allowed to warm up slowly to room temperature, and stirring was continued at room temperature for 1 hour. Subsequently, the reaction mixture was slowly poured into crushed ice and a yellow solid was precipitated. The solid product was collected by filtration and washed well with cold water to afford 2-bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine as a yellow solid (21.76 g, 88.7% yield). Mass spectrometry analysis (ES+): m/z 244.87.

References

[1] Patent: WO2012/178123, 2012, A1. Location in patent: Page/Page column 64

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine synthesis

24241-18-7
1416740-16-3
Synthesis of 2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine from 2-Amino-3,5-dibromopyrazine

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine Preparation Products And Raw materials

Raw materials

2-Amino-3,5-dibromopyrazine

Preparation Products

2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
SuZhou ShiYa Biopharmaceuticals, Inc. 0512-0512-52358471 17715136450 sales@shiyabiopharm.com China 9814 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Jiangsu aikang biomedical research and development co., LTD 025-58859352 17714375163 qzhang@aikonchem.com China 15525 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
TCI (Shanghai) Chemical Trading Co., Ltd. 021-61109150 sales@tcisct.com China 29717 58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd 2383948258 19172820304 2383948258@qq.com China 12983 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39662 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50460 58
Shanghai Jieshikai Biotechnology Co. , Ltd. 021-57520305 13795461237 zhuruyan@jskchem.com China 49221 58
Hefei Molybdenum Kai Pharmaceutical Technology Co., Ltd 18001872185; 18001872185 690231469@qq.com China 18392 58
Supplier Advantage
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Jiangsu aikang biomedical research and development co., LTD 58
Energy Chemical 58
TCI (Shanghai) Chemical Trading Co., Ltd. 58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd 58
Bide Pharmatech Ltd. 58
Beijing Solarbio Science & Tecnology Co., Ltd. 58
Shanghai Jieshikai Biotechnology Co. , Ltd. 58
Hefei Molybdenum Kai Pharmaceutical Technology Co., Ltd 58
2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine 2-BROMO-7-NITRO-5H-PYRROLO[3,2-B]PYRAZINE 5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-7-nitro- 1416740-16-3