Pan-RAS-IN-1
- CAS No.
- 1835283-94-7
- Chemical Name:
- Pan-RAS-IN-1
- Synonyms
- Ras-IN-3144;Pan-RAS-IN-1;Pan-RAS inhibitor 1;pan-Ras inhibitor 3144;Ras-IN-3144，Pan-RAS-IN-1;Pan-RAS-IN-1, 10 mM in DMSO;pan-Ras inhibitor 3144 (Compound 3144);PanRASIN1,inhibit,Ras,Pan RAS IN 1,Inhibitor;4-Piperidinecarboxamide, 4-amino-N-[3-[5-[[4-[(2,6-dichlorophenyl)methyl]-1-piperazinyl]methyl]-3-[4-(trifluoromethoxy)phenyl]-1H-indol-1-yl]propyl]-
- CBNumber:
- CB53171698
- Molecular Formula:
- C36H41Cl2F3N6O2
- Molecular Weight:
- 717.65
- MDL Number:
- MFCD31382126
- MOL File:
- 1835283-94-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Pan-RAS-IN-1 99.87% | CS-6466 | 1mg | $180 |
| Pan-RAS-IN-1 99.87% | CS-6466 | 5mg | $420 |
| Pan-RAS-IN-1 99.87% | CS-6466 | 10mg | $720 |
| Pan-RAS-IN-1 99.87% | CS-6466 | 25mg | $1440 |
| Pan-RAS-IN-1 99.87% | CS-6466 | 50mg | $2340 |
Pan-RAS-IN-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6466 | Pan-RAS-IN-1 99.87% | 1835283-94-7 | 1mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-6466 | Pan-RAS-IN-1 99.87% | 1835283-94-7 | 5mg | $420 | 2021-12-16 | Buy |
| ChemScene | CS-6466 | Pan-RAS-IN-1 99.87% | 1835283-94-7 | 10mg | $720 | 2021-12-16 | Buy |
| ChemScene | CS-6466 | Pan-RAS-IN-1 99.87% | 1835283-94-7 | 25mg | $1440 | 2021-12-16 | Buy |
| ChemScene | CS-6466 | Pan-RAS-IN-1 99.87% | 1835283-94-7 | 50mg | $2340 | 2021-12-16 | Buy |
Pan-RAS-IN-1 Chemical Properties,Uses,Production
Uses
Pan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors.
in vivo
Pan-RAS-IN-1 administration results in inhibition of tumor growth over 15 days of treatment. Pan-RAS-IN-1-treated mice exhibits decreased tumor pERK levels compared with vehicle treated mice. A modest increase in cleaved caspase-3 is also observed, showing that in this model, pan-RAS-IN-1 has the capacity to induce caspase activation[1].
References
[1] Welsch ME, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 2017 Feb 23;168(5):878-889.e29. DOI:10.1016/j.cell.2017.02.006
Pan-RAS-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Pan-RAS-IN-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10000 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3505 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89689 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 997 | 58 |
View Lastest Price from Pan-RAS-IN-1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Pan-RAS-IN-1
1835283-94-7
|
US $73.00-147.00 / mg | 99.77% | 10g | TargetMol Chemicals Inc. |
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- Pan-RAS-IN-1
1835283-94-7
- US $73.00-147.00 / mg
- 99.77%
- TargetMol Chemicals Inc.
