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4-Oxo-TEMPO

4-Oxo-TEMPO Structure
4-Oxo-TEMPO structure
CAS No.
2896-70-0
Chemical Name:
4-Oxo-TEMPO
Synonyms
TEMPONE;4-OXO-TEMPO;ZJ-702;4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY;TANO;Tanone;vitamin 702;4-Oxo-2,2,6,6;Tanone radical;4-Oxo Tempo (702)
CBNumber:
CB5318995
Molecular Formula:
C9H16NO2*
Molecular Weight:
170.23
MDL Number:
MFCD00006187
MOL File:
2896-70-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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4-Oxo-TEMPO Properties

Melting point 33-38 °C
Boiling point 299.88°C (rough estimate)
Density 1.0710 (rough estimate)
vapor pressure 2.254Pa at 25℃
refractive index 1.4640 (estimate)
storage temp. 2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form Needles, Crystals or Crystalline Powder
color Orange
Water Solubility Soluble in water (partly), acetone, DMSO, 100% ethanol, and diethylether. Insoluble in water.
BRN 1818579
InChI 1S/C9H16NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h5-6H2,1-4H3
InChIKey WSGDRFHJFJRSFY-UHFFFAOYSA-N
SMILES CC1(C)CC(=O)CC(C)(C)N1[O]
LogP 0.28 at 22℃
CAS DataBase Reference 2896-70-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 7W1863PEH5
NIST Chemistry Reference 1-Piperidinyloxy, 2,2,6,6-tetramethyl-4-oxo-(2896-70-0)
EPA Substance Registry System 1-Piperidinyloxy, 2,2,6,6-tetramethyl-4-oxo- (2896-70-0)
UNSPSC Code 12352000
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273
PPE Eyeshields, Gloves, type N95 (US)
Risk Statements  36/37/38
Safety Statements  24/25
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  TN9200000
TSCA  TSCA listed
HazardClass  9
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Acute 1
REACH Registrations Active
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
1 0

4-Oxo-TEMPO price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 179485 4-Oxo-TEMPO 2896-70-0 1g $72.4 2026-04-30 Buy
Sigma-Aldrich 179485 4-Oxo-TEMPO 2896-70-0 5g $221 2026-04-30 Buy
TCI Chemical O0266 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical >95.0%(GC)(T) 2896-70-0 5g $101 2026-04-30 Buy
TCI Chemical O0266 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical >95.0%(GC)(T) 2896-70-0 25g $331 2026-04-30 Buy
Cayman Chemical 14877 TEMPONE ≥98% 2896-70-0 1g $36 2026-04-30 Buy
Product number Packaging Price Buy
179485 1g $72.4 Buy
179485 5g $221 Buy
O0266 5g $101 Buy
O0266 25g $331 Buy
14877 1g $36 Buy

4-Oxo-TEMPO Chemical Properties,Uses,Production

Description

2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS). This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy. TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.

Chemical Properties

Pink Needles

Uses

A spin label for ESR studies

Uses

Free-radical nitroxide spin probe typically used for:

  • Redox sources for anodes in lithium secondary batteries
  • Free-radical biological studies
  • Radical spin-trapping
  • Electron paramagnetic resonance studies
  • Polymer chemisty and synthesis applications

General Description

4-Oxo-TEMPO is formed by the reaction of 2,2,6,6-tetramethyl-4-piperidone (4-oxo-TMP) and 1O2. It is a stable paramagnetic product formed during the irradiation of TiO2 in aqueous suspensions.

Flammability and Explosibility

Non flammable

References

[1] ADAM WU. Nitroxyl Radical Plus Hydroxylamine Pseudo Self-Exchange Reactions: Tunneling in Hydrogen Atom Transfer[J]. Journal of the American Chemical Society, 2009, 131 33: 11985-11997. DOI: 10.1021/ja904400d
[2] LUMATA L, MERRITT M, KHEMTONG C, et al. The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy[J]. RSC Advances, 2012, 33: 12812-12817. DOI: 10.1039/c2ra21853d
[3] KINJAL PATEL. Acute antihypertensive action of nitroxides in the spontaneously hypertensive rat.[J]. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, 290 1: R37-43. DOI: 10.1152/ajpregu.00469.2005

4-Oxo-TEMPO synthesis

826-36-8
2896-70-0
Synthesis of 4-Oxo-TEMPO from Triacetonamine

4-Oxo-TEMPO Preparation Products And Raw materials

Raw materials

Preparation Products

2,2,6,6-Tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid rac-2,2,6,6-Tetramethylpiperidine-N-OXYL-4, 4-(5-spirohydantoin)

4-Oxo-TEMPO Suppliers

Global( 256)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Kaisai Chemical Co., Ltd 021-33516722 13701817765 kaisaichem@163.com China 4604 58
Wuhan Roche Technology Development Co., Ltd., 18986168071; 18986168071 18986168071@163.com China 95 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Shanghai Kaisai Chemical Co., Ltd 58
Wuhan Roche Technology Development Co., Ltd., 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Capot Chemical Co., Ltd 66

View Lastest Price from 4-Oxo-TEMPO manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Oxo-2,2,6,6-tetramethylpiperidinooxy pictures 2026-09-11 4-Oxo-2,2,6,6-tetramethylpiperidinooxy
2896-70-0
 1KG 99% 500mt Jinan Finer Chemical Co., Ltd
4-Oxo-2,2,6,6-tetramethylpiperidinooxy pictures 2026-08-25 4-Oxo-2,2,6,6-tetramethylpiperidinooxy
2896-70-0
 $2.20-8.80 1kg 99%min 1000kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Tempone pictures 2026-07-27 Tempone
2896-70-0
 98.18% 10g TargetMol Chemicals Inc.
  • Tempone pictures
  • Tempone
    2896-70-0
  • $0.00
  • 98.18%
  • TargetMol Chemicals Inc.

4-Oxo-TEMPO Spectrum

4-Oxo-2,2,6,6-tetramethylpiperidinooxy(2896-70-0)IR14-Oxo-2,2,6,6-tetramethylpiperidinooxy(2896-70-0)Raman4-Oxo-2,2,6,6-tetramethylpiperidinooxy(2896-70-0)ESR

2896-70-0(4-Oxo-TEMPO)Related Search:

PENICILLIN V TEMPO Triacetonediamine 1,1'-Carbonyldiimidazole 2,2,6,6-Tetramethylpiperidine
2,2,6,6-Tetramethyl-4-piperidinol 4-Methylenepiperidine HCl 1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine Carbonyl iron powder 3,5-Dibromo-4-oxo-2,2,6,6-tetramethylpiperidin-1-yl
4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-D16-1-OXYL 4-Oxo-2,2,6,6-tetramethylpiperidine-d16,1-15N-1-oxyl 4-Oxo-2,2,6,6-tetramethylpiperidinooxy 4-Oxo-2,2,6,6-tetramethylpiperidine-1-15N-1-oxyl 1-Hydroxy-2 2 6 6-tetramethyl-4-piperi-
1-Benzoyloxy-2,2,6,6-tetramethyl-4-oxopiperidine 1-Acetyloxy-2,2,6,6-tetramethyl-4-oxopiperidine

1of4

4-Oxo-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical 4-OXO-TEMPO, FREE RADICAL 80+% 4-OXO-TEMPO, FREE RADICAL 99+% 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOXY 4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxyl(4-Oxo-TEMPO,freeradical) 4-Oxo-2,2,6,6 4-Oxo-2,2,6,6-trtramethyl-1-piperidi nyloxy,free radical 2,2,6,6-Tetramethyl-4-piperidone 1-oxyl, free radical 2,2,6,6-TETRAMETHYL-4-PIPERIDONE 1-OXYL 4-OXO-TEMPO 4-OXO-TEMPO, FREE RADICAL 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY, FREE RADICAL 4-OXO-2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY 4-OXO-2,2,6,6-TETRAMETHYL-4-PIPERIDINYLOXY 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL 2,2,6,6-TETRAMETHYLPIPERID-4-ONE-1-OXYL 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical 4-OXO-TEMPO ---ORANGE SOLID, SPIN LABEL, PURITY 99%--- 4-Oxo-2,2,6,6-tetramethylpiperidinooxy, 95%, free radical (2,2,6,6-Tetramethyl-4-oxopiperidinooxy)radical (2,2,6,6-Tetramethyl-4-oxopiperidinyloxy)radical [(4-Oxo-2,2,6,6-tetramethylpiperidine-1-yl)oxy]radical 1-Piperidinyloxy radical, 2,2,6,6-tetramethyl-4-oxo- 2,2,6,6-tetramethyl-4-oxo-1-piperidinylox 2,2,6,6-tetramethyl-4-oxo-piperidin-1-oxyl 2,2,6,6-tetramethyl-4-oxo-piperidinoox 2,2,6,6-Tetramethyl-4-oxo-piperidinoxy 2,2,6,6-Tetramethyl-4-piperidone 1-nitroxide 2,2,6,6-Tetramethylpiperidone-1-oxyl 4-Oxo-2,2,6,6-tetramethylpiperidinooxyl Piperidinooxy, 2,2,6,6-tetramethyl-4-oxo- TANO Tanone Tanone radical 4-oxo-2,2,6,6-tetramethyl piperidone -1-oxyl 4-Oxo Tempo (702) 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical(purified by sublimation) 4-Oxo TeMpo, free radical (4-Oxo-2,2,6,6-TetraMethyl-4-Piperidinyloxy, free radical) 4-Oxo-2,2,6,6-tetraMethylpiperidinoxy (4-oxo-TeMpo) 4-Oxo-2,2,6,6-trtramethyl-1-piperidinyloxy 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl  Triacetoneamine nitroxide Triacetoneamine N-oxyl triacetoneamine-n-oxyl TIMTEC-BB SBB008633 1-OXYL-2,2,6,6-TETRAMETHYL-4-PIPERIDONE 2,2,6,6-TETRAMETHYL-4-OXO-1-PIPERIDINYLOXY 2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINOOXY 4-Oxo-2,2,6,6-tetramethylpiperidine1-OxylFreeRadical> 4-Oxo-tempo[4-Oxo-TEMPO] 4-Oxo-TEMPO, free radical, 96%, 1-(1H-1,3-BENZODIAZOL-2-YL)-1H-PYRAZOL-9-AMINE Oxo-2,2,6,6-tetramethylpiperidinooxy vitamin 702 Polycondensation inhibitor 702 / 4-Oxo-TEMPO Polymerization inhibitor ZJ-702) 4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxylRadical PolymerizationInhibitor702(NitroxideRadicalPiperidone)