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3-(4-Chlorophenyl)-2-cyanoacrylic acid

CAS No.
20374-46-3
Chemical Name:
3-(4-Chlorophenyl)-2-cyanoacrylic acid
Synonyms
(E)-3-(4-Chlorophenyl)-2-cyanoacrylic acid;4-Chloro-α-cyanocinnamic Acid;4-chloro-.alpha.-Cyanocinnamic Acid;4-chloro-α-Cyanocinnamic Acid (Cl-CCA);3-(4-Chlorophenyl)-2-cyanoacrylic acid;(E)-3-(4-chlorophenyl)-2-cyano-2-propenoate;(2E)-3-(4-Chlorophenyl)-2-cyanoacrylic acid;(E)-2-Cyano-3-(naphthalen-2-yl)acrylic Acid;(2E)-3-(4-Chlorophenyl)-2-cyano-2-propenoic Acid;trans-3-(4-Chlorophenyl)-2-cyanoprop-2-enoic acid
CBNumber:
CB5322299
Molecular Formula:
C10H6ClNO2
Molecular Weight:
207.61
MDL Number:
MFCD02317172
MOL File:
20374-46-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:29

3-(4-Chlorophenyl)-2-cyanoacrylic acid Properties

Melting point 191-193
Boiling point 377.0±32.0 °C(Predicted)
Density 1.415±0.06 g/cm3(Predicted)
solubility DMF: 14 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 14 mg/ml
form A crystalline solid
pka 0.55±0.10(Predicted)
CAS DataBase Reference 20374-46-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2926907090
NFPA 704
0
3 0

3-(4-Chlorophenyl)-2-cyanoacrylic acid price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9000981 4-chloro-α-Cyanocinnamic Acid ≥98% 20374-46-3 5mg $40 2026-04-30 Buy
Cayman Chemical 9000981 4-chloro-α-Cyanocinnamic Acid ≥98% 20374-46-3 10mg $77 2026-04-30 Buy
Cayman Chemical 9000981 4-chloro-α-Cyanocinnamic Acid ≥98% 20374-46-3 25mg $171 2026-04-30 Buy
Cayman Chemical 9000981 4-chloro-α-Cyanocinnamic Acid ≥98% 20374-46-3 50mg $302 2026-04-30 Buy
ChemScene CS-0784962 4-Chloro-α-cyanocinnamic acid ≥98% 20374-46-3 5mg $47 2026-06-04 Buy
Product number Packaging Price Buy
9000981 5mg $40 Buy
9000981 10mg $77 Buy
9000981 25mg $171 Buy
9000981 50mg $302 Buy
CS-0784962 5mg $47 Buy

3-(4-Chlorophenyl)-2-cyanoacrylic acid Chemical Properties, Uses, Production

Description

4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).

Uses

4-Chloro-α-cyanocinnamic Acid (cas# 20374-46-3) is a compound useful in organic synthesis.

3-(4-Chlorophenyl)-2-cyanoacrylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

3-(4-Chlorophenyl)-2-cyanoacrylic acid Suppliers

Global Suppliers ( 54)
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Tianjin Being Technology Co., Ltd. 18622939839 tjby921@163.com China 615 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3307 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
(2E)-3-(4-Chlorophenyl)-2-cyanoacrylic acid 4-Chloro-α-cyanocinnamic Acid trans-3-(4-Chlorophenyl)-2-cyanoprop-2-enoic acid (2E)-3-(4-Chlorophenyl)-2-cyano-2-propenoic Acid (E)-2-Cyano-3-(naphthalen-2-yl)acrylic Acid (2E)-3-(4-Chlorophenyl)-2-cyanoprop-2-enoic acid, trans-4-Chloro-alpha-cyanocinnamic acid 4-chloro-.alpha.-Cyanocinnamic Acid (E)-3-(4-chlorophenyl)-2-cyano-2-propenoate 2-Propenoic acid, 3-(4-chlorophenyl)-2-cyano-, (2E)- 4-chloro-α-Cyanocinnamic Acid (Cl-CCA) (E)-3-(4-Chlorophenyl)-2-cyanoacrylic acid 3-(4-Chlorophenyl)-2-cyanoacrylic acid 20374-46-3 C10H6ClNO2 Aromatics Labeling and Diagnostics Reagents