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BETA-POMPILIDOTOXIN

CAS No.
216064-36-7
Chemical Name:
BETA-POMPILIDOTOXIN
Synonyms
β-PMTX;BETA-PMTX;POMPILIDOTOXIN;β-Pompilidotoxin;b-Pompilidotoxin;RIKIGLFDQLSRL-NH2;BETA-POMPILIDOTOXIN;L-Leucinamide, L-arginyl-L-isoleucyl-L-lysyl-L-isoleucylglycyl-L-leucyl-L-phenylalanyl-L-α-aspartyl-L-glutaminyl-L-leucyl-L-seryl-L-arginyl-
CBNumber:
CB5324309
Molecular Formula:
C71H124N22O17
Molecular Weight:
1557.88
MDL Number:
MFCD03788007
MOL File:
216064-36-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-25 07:39:42

BETA-POMPILIDOTOXIN Properties

storage temp. −20°C
solubility ≥155.8 mg/mL in DMSO; insoluble in EtOH; ≥22.05 mg/mL in H2O
form solid
color White to off-white
Water Solubility Soluble to 1 mg/ml in water
Sequence Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-NH2

SAFETY

Risk and Safety Statements

WGK Germany  3

BETA-POMPILIDOTOXIN price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth RIA06436 β-Pompilidotoxin 216064-36-7 10mg $1165.6 2026-06-05 Buy
Biosynth RIA06436 β-Pompilidotoxin 216064-36-7 25mg $1900.5 2026-06-05 Buy
Biosynth RIA06436 β-Pompilidotoxin 216064-36-7 50mg $3041 2026-06-05 Buy
ChemScene CS-0027628 β-Pompilidotoxin 216064-36-7 1mg $54 2026-06-04 Buy
ChemScene CS-0027628 β-Pompilidotoxin 216064-36-7 5mg $130 2026-06-04 Buy
Product number Packaging Price Buy
RIA06436 10mg $1165.6 Buy
RIA06436 25mg $1900.5 Buy
RIA06436 50mg $3041 Buy
CS-0027628 1mg $54 Buy
CS-0027628 5mg $130 Buy

BETA-POMPILIDOTOXIN Chemical Properties,Uses,Production

Uses

β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells[1].

Biological Activity

β-pompilidotoxin, (c71h124n22o17), a peptide with the sequence h2n-arg-ile-lys-ile-gly-leu-phe-asp-gln-leu-ser-arg-leu-amide, mw= 1557.88. pompilidotoxin is a toxin from the venom of spider wasps that slows the inactivation of na+channels. α-pompilidotoxin (α-pmtx) can be extracted from the venom of a solitary wasp, anopolis samariensis. β-pompilidotoxin (β-pmtx) originates from the venom of another wasp, batozonellus maculifrons(1). homology α-pmtx has no structural homology with other toxins. it lacks disulfide bonds which are known to be present in other toxins acting on sodium channels, such as sea anemone toxins or scorpion toxins(2). both α- and β-pmtx slow the inactivation of neuronal sodium channels (but not heart sodium channels), possibly by binding to the neurotoxin receptor site 3 on the extracellular surface of the sodium channel(3). β-pmtx has higher potency than α-pmtx. by slowing down the inactivation of sodium channels, pmtxs can potentiate synaptic transmission in the lobster neuromuscular endplate.figure1 formula of β-pompilidotoxin

References

1. Konno K, Hisada M, Itagaki Y, Naoki H, Kawai N, Miwa A, Yasuhara T, Takayama H (1998). "Isolation and structure of pompilidotoxins, novel peptide neurotoxins in solitary wasp venoms". Biochem Biophys Res Commun. 250 (3): 612–6.2. Sahara Y, Gotoh M, Konno K, Miwa A, Tsubokawa H, Robinson HP, Kawai N (2000). "A new class of neurotoxin from wasp venom slows inactivation of sodium current". Eur J Neurosci. 12 (6): 1961–70.3. Kawai N, Konno K (2004). "Molecular determinants of two neurotoxins that regulate sodium current inactivation in rat hippocampal neurons". Neurosci Lett. 361 (1-3): 44–6.

BETA-POMPILIDOTOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

BETA-POMPILIDOTOXIN Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
ApexBio Technology LLC +1-832-696-8203 info@apexbt.com United States 477 60
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19087 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 0571-87213919 17306812703 3007955328@qq.com China 7446 58
Shanghai HongTide Biotechnology Co.,Ltd. 15318089928 alex@hanhonggroup.com China 4604 58

View Lastest Price from BETA-POMPILIDOTOXIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BETA-POMPILIDOTOXIN pictures 2026-07-24 BETA-POMPILIDOTOXIN
216064-36-7
1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd

BETA-POMPILIDOTOXIN Spectrum

216064-36-7(BETA-POMPILIDOTOXIN)Related Search:

BETA-PMTX BETA-POMPILIDOTOXIN RIKIGLFDQLSRL-NH2 b-Pompilidotoxin β-PMTX β-Pompilidotoxin L-Leucinamide, L-arginyl-L-isoleucyl-L-lysyl-L-isoleucylglycyl-L-leucyl-L-phenylalanyl-L-α-aspartyl-L-glutaminyl-L-leucyl-L-seryl-L-arginyl- POMPILIDOTOXIN 216064-36-7 C71H124N22O17 Sodium Channel Modulators Voltage-gated Ion Channels Other Sodium Channel Modulators Ion Channels Monovalent Ion Channels Cell Signaling and Neuroscience Cell Biology BioChemical