1,2,3,5-Tetramethylbenzene
- CAS No.
- 527-53-7
- Chemical Name:
- 1,2,3,5-Tetramethylbenzene
- Synonyms
- Benzene, 1,2,3,5-tetramethyl-;Tetramethylbenzene;ISODURENE;IZODURENE;DC04750000;Imidaprilat Impurity 7;1,3,4,5-tetramethylbenzene;1,2,3,5-tetramethyl-benzen;1,2,3,5-Tetramethylbenzene;1,2,3,5-Tetramethtylbenzene
- CBNumber:
- CB5327850
- Molecular Formula:
- C10H14
- Molecular Weight:
- 134.22
- MDL Number:
- MFCD00008524
- MOL File:
- 527-53-7.mol
- MSDS File:
- SDS
| Melting point | -24° |
|---|---|
| Boiling point | 198°C |
| Density | 0,89 g/cm3 |
| refractive index | n20/D 1.512(lit.) |
| Flash point | 63°C |
| Water Solubility | Insoluble in water |
| form | clear liquid |
| color | Colorless to Light yellow to Light orange |
| Merck | 14,5166 |
| Henry's Law Constant | 1.2×10-3 mol/(m3Pa) at 25℃, Zhang et al. (2010) |
| InChI | 1S/C10H14/c1-7-5-8(2)10(4)9(3)6-7/h5-6H,1-4H3 |
| InChIKey | BFIMMTCNYPIMRN-UHFFFAOYSA-N |
| SMILES | Cc1cc(C)c(C)c(C)c1 |
| LogP | 4.100 |
| CAS DataBase Reference | 527-53-7(CAS DataBase Reference) |
| FDA UNII | 0JBI5Y5A5Z |
| EPA Substance Registry System | 1,2,3,5-Tetramethylbenzene (527-53-7) |
| UNSPSC Code | 12352103 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38-36 | |||||||||
| Safety Statements | 26-36/37/39-24/25-23-45 | |||||||||
| RIDADR | 3082 | |||||||||
| WGK Germany | WGK 2 | |||||||||
| RTECS | DC0475000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2902.90.3050 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| Excepted Quantities | Non-Hazardous | |||||||||
| NFPA 704 |
|
1,2,3,5-Tetramethylbenzene price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS000400 | 1,2,3,5-Tetramethylbenzene AldrichCPR | 527-53-7 | 1G | $93.2 | 2026-04-30 | Buy |
| TCI Chemical | T4287 | 1,2,3,5-Tetramethylbenzene min. 90.0 % | 527-53-7 | 5ML | $159 | 2026-04-30 | Buy |
| TCI Chemical | T0565 | 1,2,3,5-Tetramethylbenzene >70.0%(GC) | 527-53-7 | 5mL | $150 | 2024-03-01 | Buy |
| TCI Chemical | T0565 | 1,2,3,5-Tetramethylbenzene >70.0%(GC) | 527-53-7 | 25mL | $512 | 2024-03-01 | Buy |
| aablocks | AA003D7O | 1,2,3,5-Tetramethylbenzene 98% | 527-53-7 | 1g | $19 | 2026-05-28 | Buy |
1,2,3,5-Tetramethylbenzene Chemical Properties, Uses, Production
Chemical Properties
clear colourless to pale yellow liquid
Uses
Organic synthesis.
Synthesis Reference(s)
Journal of the American Chemical Society, 79, p. 6277, 1957 DOI: 10.1021/ja01580a044
Organic Syntheses, Coll. Vol. 2, p. 360, 1943
General Description
A pale yellow to white liquid with a camphor-like odor. Flash point 165°F. Less dense than water and only negligibly soluble in water. Slightly irritates the skin and eyes. Slightly toxic by ingestion but may irritate the mouth, throat and gastrointestinal tract.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as 1,2,3,5-TETRAMETHYLBENZENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.
Hazard
Liquid. Soluble in alcohol and ether; insoluble in water. Combustible.
Health Hazard
CALL FOR MEDICAL AID. LIQUID: Irritating to skin, eyes, and respiratory tract. Remove contaminated clothing and shoes. Flush affected areas with plenty of water. IF IN EYES, hold eyelids open and flush with plenty of water. VAPORS: Irritating to skin, eyes and respiratory tract. Move to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen. IF IN EYES, hold eyelids open and flush with plenty of water. Harmful if inhaled or swallowed. Vapor or mist is irritating to the eyes, mucous membranes, and upper respiratory tract. Prolonged contact can cause dermititis, and prolonged exposure can cause nausea, dizziness and headache.
Fire Hazard
Combustible.
Purification Methods
Reflux isodurene over sodium and distil it under reduced pressure. [Smith Org Synth Coll Vol II 248 1943, Beilstein 5 H 430, 5 II 329, 5 III 976, 5 IV 1073.]
1,2,3,5-Tetramethylbenzene Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2277 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
