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Chloropyramine

Chloropyramine Structure
Chloropyramine structure
CAS No.
59-32-5
Chemical Name:
Chloropyramine
Synonyms
Allergan;Synpen;Avapena;Synopen;synopenr;allergans;Suprastin;Synopen R;Allergan S;Anaphylline
CBNumber:
CB5327911
Molecular Formula:
C16H20ClN3
Molecular Weight:
289.8
MDL Number:
MFCD00065266
MOL File:
59-32-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:50:52
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Chloropyramine Properties

Melting point 25°C
Boiling point bp0.2 154-155°
Density 1.1031 (rough estimate)
refractive index 1.6010 (estimate)
pka 9.00±0.28(Predicted)
EWG's Food Scores 1
FDA UNII 2K3L8O9SOV
NIST Chemistry Reference Chloropyramine(59-32-5)
ATC code D04AA09,R06AC03,R06AC53

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
REACH Registrations Active

Chloropyramine price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01E8M5 Chloropyramine ≥98% 59-32-5 5g $475 2026-05-30 Buy
aablocks AA01E8M5 Chloropyramine ≥98% 59-32-5 10g $825 2026-05-30 Buy
aablocks AA01E8M5 Chloropyramine ≥98% 59-32-5 25g $1338 2026-05-30 Buy
aablocks AA01E8M5 Chloropyramine ≥98% 59-32-5 50g $2200 2026-05-30 Buy
Biosynth FC164737 Chloropyramine 59-32-5 1g $75 2021-12-16 Buy
Product number Packaging Price Buy
AA01E8M5 5g $475 Buy
AA01E8M5 10g $825 Buy
AA01E8M5 25g $1338 Buy
AA01E8M5 50g $2200 Buy
FC164737 1g $75 Buy

Chloropyramine Chemical Properties, Uses, Production

Uses

Chloropyramine is used for allergic dermatosis, allergic rhinitis and conjunctivitis, for drug-induced allergies, in the beginning stages of bronchial asthma, eczema, neurodermatitis, contact dermatitis, and toxicodermia. It also exhibits a sedative effect. Synonyms of this drug are suprastin, chlortripelenamine, and synopen.

Definition

ChEBI: N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridinyl)ethane-1,2-diamine is an aminopyridine.

Synthesis

Chloropyramine, N-(4-chlorobenzyl)-N,N-dimethyl-N-2-pyridylethylenediamine (16.1.9), is synthesized in a somewhat different manner, which is by reacting 2-brompyridine with N-(4-chlorobenzyl)-N,N-dimethylethylenediamine (16.1.8). N-(4-Chlorobenzyl)-N,N-dimethylethylenediamine (16.1.8), in turn, is synthesized by condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent reduction of the imine group.

Synthesis_59-32-5

in vivo

Chloropyramine (i.p.; 10 mg/kg) abolishes hypothermia in rats[2].

Animal Model:Rats[2]
Dosage:10 mg/kg
Administration:Intraperitoneal
Result:Reduced histamine-induced hypothermia.

IC 50

H1 Receptor

Chloropyramine synthesis

504-29-0
59-32-5
Synthesis of Chloropyramine from 2-Aminopyridine

Chloropyramine Preparation Products And Raw materials

Raw materials

Benzenecarbothioamide, 4-chloro-N-[2-(dimethylamino)ethyl]-N-2-pyridinyl- 1,2-Ethanediamine, N'-[(4-chlorophenyl)methyl]-N,N-dimethyl- 2-(2-pyridylamino)ethyldimethylamine (4-Chloro-benzyl)-pyridin-2-yl-amine dihydrochloride 2-Bromopyridine
2-Aminopyridine

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Preparation Products

Chloropyramine Suppliers

Global Suppliers ( 24)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 17705817739 info@dycnchem.com China 52451 58
AFINE CHEMICALS LIMITED +86-571-85134551 +86-18958018566 info@afinechem.com China 15030 58
Shaanxi Dideu Medichem Co. Ltd +86-29-81139210 +86-17392587031 1059@dideu.com China 9789 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49906 58
Hubei Wande Chemical Co., Ltd 15377098680 15377098680 1148280011@qq.com China 9436 58
Shaanxi Dideu Medichem Co. Ltd 029-81024372 17792795018 1053@dideu.com China 9999 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Supplier Advantage
BOC Sciences 65
Quality Control Solutions Ltd. 56
Shanghai EFE Biological Technology Co., Ltd. 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
AFINE CHEMICALS LIMITED 58
Shaanxi Dideu Medichem Co. Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Hubei Wande Chemical Co., Ltd 58
Shaanxi Dideu Medichem Co. Ltd 58
TargetMol Chemicals Inc. 58

View Latest Price from Chloropyramine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Chloropyramine pictures 2026-05-11 Chloropyramine
59-32-5
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

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1,2-Ethanediamine, N-[(4-chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl- 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-pyridin 2-((p-Chlorobenzyl)(2-(dimethylamino)ethyl)amino)pyridine Allergan Allergan S n-(p-chlorobenzyl)-n',n'-dimethyl-n-(2-pyridyl)ethylenediamine CHLOROPYRAMINE BASE CHLOROPYRAMINE 2-[(4-chlorobenzyl)[2-(dimethylamino)ethyl]amino]pyridine allergans Anaphylline Avapena Chlorneoantergan Chloroneoantergan Chloropyribenzamine Chlorpyramine Ethylenediamine, N-(p-chlorobenzyl)-N',N'-dimethyl-N-(2-pyridyl)- Halopyramine n-((4-chlorophenyl)methyl)-n’,n’-dimethyl-n-2-pyridinyl-2-ethanediamine n-(p-chlorobenzyl)-n’,n’-dimethyl-n-(2-pyridyl)-ethylenediamin p-Chlorbenzyl-alpha-pyridyl-dimethyl-aethylendiamin Pyridine, 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)- Suprastin Synopen Synopen R synopenr Synpen N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine 1,2-Ethanediamine, N1-[(4-chlorophenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl- Chloropyramine USP/EP/BP FAK inhibitor C4 59-32-5 69-32-5 C16H20ClN3