Fluroxypyr
- CAS No.
- 69377-81-7
- Chemical Name:
- Fluroxypyr
- Synonyms
- ADVANCE;4-amino-3,5-dichloro-6-fluoro-2-pyridyloxyaceticacid;((4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy)-aceticaci;[(4-Amino-3,5-dichloro-6-fluoropyridin-2-yl)oxy]acetic acid;ef-689;ff4014;FLUROXYPYR;Advance(TM);Fluroxypyr(Starane);Fluroxypyr Solution
- CBNumber:
- CB8389671
- Molecular Formula:
- C7H5Cl2FN2O3
- Molecular Weight:
- 255.03
- MDL Number:
- MFCD01311822
- MOL File:
- 69377-81-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 57.5°C |
|---|---|
| Boiling point | 399.4±37.0 °C(Predicted) |
| Density | 1.3 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 2.22±0.10(Predicted) |
| color | White to Off-White |
| Merck | 13,4229 |
| BRN | 7136185 |
| Henry's Law Constant | 5.7×105 mol/(m3Pa) at 25℃, HSDB (2015) |
| Major Application |
agriculture environmental |
| InChI | 1S/C7H5Cl2FN2O3/c8-3-5(11)4(9)7(12-6(3)10)15-1-2(13)14/h1H2,(H2,11,12)(H,13,14) |
| InChIKey | MEFQWPUMEMWTJP-UHFFFAOYSA-N |
| SMILES | Nc1c(Cl)c(F)nc(OCC(O)=O)c1Cl |
| LogP | 3.160 (est) |
| CAS DataBase Reference | 69377-81-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 8O40SHO197 |
| NIST Chemistry Reference | Fluroxypyr(69377-81-7) |
| EPA Substance Registry System | Fluroxypyr (69377-81-7) |
| Pesticides Freedom of Information Act (FOIA) | Fluroxypyr |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H412 |
| Precautionary statements | P273-P501 |
| PPE | Eyeshields, Faceshields, Gloves |
| Risk Statements | 52/53 |
| Safety Statements | 61 |
| RIDADR | UN3077(solid) |
| WGK Germany | 2 |
| RTECS | AF2500000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 3 |
| Hazardous Substances Data | 69377-81-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 2405 mg/kg; i.p. in male, female rats: 458, 519 mg/kg; percutaneous in rabbits >5000 mg/kg (Paul) |
Fluroxypyr price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 45758 | Fluroxypyr PESTANAL?, analytical standard | 69377-81-7 | 100mg | $87.2 | 2026-04-30 | Buy |
| TRC | TRC-F598780-500MG | Fluroxypyr >95%(HPLC) | 69377-81-7 | 500mg | $511 | 2026-06-03 | Buy |
| TRC | TRC-F598780-250MG | Fluroxypyr >95%(HPLC) | 69377-81-7 | 250mg | $294 | 2026-06-03 | Buy |
| TRC | TRC-F598780-100MG | Fluroxypyr >95%(HPLC) | 69377-81-7 | 100mg | $138 | 2026-06-03 | Buy |
| Biosynth | FF100293 | Fluroxypyr | 69377-81-7 | 0.25g | $900 | 2026-06-04 | Buy |
Fluroxypyr Chemical Properties, Uses, Production
Description
Fluroxypyr is a post-emergence herbicide used to control economically important broad-leaved weeds. It is highly soluble in water and has a low volatility. It tends not to be persistent in soil or water-sediment systems. There is little potential for it to leach to groundwater. No significant risks to human health have been identified other than some indication it may be a neurotoxin and oral mammalian toxicity is low. Toxicity to biodiversity is low to moderate.
Chemical Properties
White crystalline solid.
Uses
Fluroxypyr is a systemic and selective herbicide. Fluroxypyr is used for the control of broad-leaved weeds in small grain cereals, maize, pastures, range land and turf. Fluroxypyr is a synthetic auxin.
Production Methods
Fluroxypyr is commercially produced through a multi-step synthesis involving pyridine-based intermediates. The process typically begins with the preparation of halogenated pyridines, which are then reacted with alcohols or esters to form fluroxypyr esters such as fluroxypyr-meptyl or fluroxypyr-1-methylheptyl ester. These reactions involve esterification and halogen substitution steps under controlled conditions using solvents and catalysts to ensure high yield and purity.
Definition
ChEBI: An aminopyridine that is pyridin-4-amine substituted by chloro groups at positions 3 and 5, a fluoro group at position 6 and a carboxymethoxy group at position 2.
Trade name
methyl ester: AGROSTAR; BOFIX FFC®; CABADEX®; CASCADE®; DOWCO® 433 MHE; FOREFRONT®; GALAXY GL184®; PARADIGM®; PASTUREGARD®; STARANE®; TOMAHAWK®; VISTA®; WIDEMATCH®, (fluroxypyr + clopyralid); XRM-5084®
Mechanism of action
Foliar uptake causing auxin-type response. Synthetic auxin.
Potential Exposure
Those who manufacture, distribute or use this pyridinecarboxylic acid/pyridine herbicide.
Environmental Fate
The DT50 in soil is relatively short, ranging from 5 to 9 days in experiments conducted in the laboratory. This rapid degradation is due to microbes.Because of its rapid soil degradation, little fluroxypyr is available for other dissipation processes, e.g., leaching.
Metabolism
Fluroxypyr is stable under acidic conditions
and moderately stable in alkaline conditions; e.g., the
DT50 in water at pH 9 is 185 days. Degradation occurs at
temperatures above its melting point. Fluroxypyr is stable
in light.
Plant. The metabolism of fluroxypyr has not been fully
described. Conjugates of fluroxypyr have been observed in
tolerant plants.
Soil. Fluroxypyr is rapidly metabolized by soil
microbes via the removal of the carboxyl group or
acetic acid group, yielding 4-amino-3,5-dichloro-6-fluoro-
2-methoxypyridine, and 4-amino-3,5-dichloro-6-fluoro-2-
pyridinol, respectively.
Shipping
UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz ardous material, Technical Name Required.
Toxicity evaluation
Mammalian Toxicity. Fluroxypyr appears to be rapidly
excreted, unmodified, in the urine of animals. The acute
oral LD50 for rat is 2405 mg/kg.
Weed Resistance/Modified Crop Tolerance. Fuerst et al.
(48) reported fluroxypyr resistance in yellow starthistle
(Centaurea solstitialis). No crops with modified tolerance
toward fluroxypyr are currently in production.
Incompatibilities
May not be compatible with nitrates. Moisture may cause hydrolysis or other forms of decompo sition; forming a strong acid. Temperatures above 250℃ can cause decomposition. Methyl ester: Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is suffi ciently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solu tions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Waste Disposal
Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an after burner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesti cide containers.
Pesticide Type
Herbicide
Fluroxypyr Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Shanghai Fuhe Chemistry Technology Co., Ltd. | 0086-21-67651709 | cfx759@hotmail.com | China | 409 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
| TianJin Alta Scientific Co., Ltd. | 022-65378550-8551 | contact@altascientific.com | China | 2772 | 58 |
View Latest Price from Fluroxypyr manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Fluroxypyr
69377-81-7
|
1kg | 99 | 20tons | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2026-07-14 | Fluroxypyr
69377-81-7
|
1kg | 99 | 20tons | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2026-03-20 | Fluroxypyr
69377-81-7
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Fluroxypyr
69377-81-7
- $0.00
- 99
- Qingdao Trust Agri Chemical Co.,Ltd
-
- Fluroxypyr
69377-81-7
- $0.00
- 99
- Qingdao Trust Agri Chemical Co.,Ltd
-
- Fluroxypyr
69377-81-7
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
